Comparing MRI to CT on Pediatric Craniosynostosis.


About this study

To establish whether ZTE imaging of the infant calvarium can provide equivalent information to CT, specifically in reference to diagnosis for craniosynostosis.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Eligibility criteria - Inclusion: 

Pediatric patients 0-18 of age will be recruited by our surgical colleagues based on the clinical concern for craniosynostosis and possible need for calvarial reconstruction.

Eligibility criteria - Exclusion: 

Exclusion criteria include lack of consent, contraindication/inability to undergo both examinations within the designated time period and/or undiagnostic image quality.

Patients will undergo both CT and ZTE within a 6 week time period (though attempting with each patient to schedule on the same day). ZTE MRI examinations will be added, when possible, to a patient’s already scheduled MRI or will take place as a standalone appointment without sedation.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Julie Guerin, M.D.

Open for enrollment

Contact information:

Suson Walsh CCRP

(507) 293-0039

More information


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