A Study to Evaluate the Effectiveness of Psychological Support Based on Positive Suggestions on Mental Health Morbidity and Cognitive Function


About this study

The purpose of this trial is to compare the effectiveness of psychological support based on positive suggestions (PSBPS) vs. usual care on mental health morbidity and cognitive function in survivors of critical illness.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Critically ill patients with either ARF on mechanical ventilation or requiring vasopressors or both  admitted to the ICU and expected ICU stay > 48 hours.

Exclusion Criteria: 

  • Patients with a history of dementia.
  • Patients with intellectual disability.
  • Patients who have attempted suicide.
  • Patients with psychotic disorders such as schizophrenia, acute alcohol/substance intoxication or withdrawal.
  • Patients with severe metabolic encephalopathy.
  • Patients with any form of cognitive impairment significant enough to preclude patient from completing study questionnaires.
  • Patients on comfort care.
  • Patients not expected to survive the hospital stay.
  • Non-English speaking patients.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Lioudmila Karnatovskaia, M.D.

Open for enrollment

Contact information:

Anesthesia Clinical Research Unit

(507) 422-0582

More information


Publications are currently not available