About this study

The purpose of this study is to better understand Antiphospholipid syndrome (APS) pathophysiology and to aid development of targeted therapeutics.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age 18 or older.
  • Able to read, understand, and give written informed consent.
  • Receiving or have received care at the Mayo Clinic Rheumatology outpatient clinic in Rochester.
  • Patients meeting the 2006 Sydney Classification Criteria for Definite APS.
  • Patients who have not had clinical events that fulfill the Sydney criteria, but have a positive antiphospholipid antibody laboratory test.

Exclusion Criteria:

  • Patients not meeting the case definitions listed above will be ineligible.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Ali Duarte Garcia, M.D.

Open for enrollment

Contact information:

Annie Streicher

(507) 422-9855

More information


Publications are currently not available