A Study to Assess Biomarkers in Patients with Osteonecrosis of the Femoral Head


About this study

The purposes of this study is to isolate RNA from bone tissues from ONFH and osteoarthritis (OA) femoral heads and perform RNA sequencing to measure gene expression.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Subjects with target disease ONFH and OA.

Exclusion Criteria: 

  • ONFH and OA subjects taking the medications statins, steroids, or TZDs will be excluded. 


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Rafael Sierra, M.D.

Open for enrollment

Contact information:

Riley Voll

(507) 284-5445


More information


Publications are currently not available