A Study to Identify Physical Function Trajectories and Biomarkers after Kidney Transplantation

Overview

About this study

The aims of this study are to identify frailty trajectories and biomarkers of frailty after kidney transplantation. Subjects will be followed beginning immediately prior to kidney transplantation until 1 year after kidney transplantation. Frailty will be prospectively assessed using performance-based measures (Fried criteria and Short Physical Impairment Battery). The relationship between frailty measures and blood levels of promising candidate biomarkers will be analyzed.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients age ≥ 18 years old.
  • Either scheduled to receive or have received a kidney transplant (KT) at Mayo Clinic Rochester, Mayo Clinic Arizona, or Mayo Clinic Florida.

Exclusion Criteria: 

  • Neuropsychiatric condition causing patient to be unable to provide consent.
  • Scheduled to receive or have received a combined organ transplant.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Elizabeth Lorenz, M.D.

Open for enrollment

Contact information:

Julie Gecox Hanson CCRP

Gecox.Julie@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Hani Wadei, M.D.

Open for enrollment

Contact information:

Katelyn Register M.S., C.C.R.C.

Register.Katelyn@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Girish Mour, M.B.B.S., M.D.

Open for enrollment

Contact information:

April Howard B.S.N., R.N.

(480) 301-5756

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available