A Study to Evaluate Potential Myocardial Injury in Patients with Cardiac Implantable Electronic Devices Undergoing Defibrillation Threshold Testing

Overview

About this study

The purpose of this study is to determine if defibrillation threshold testing (DFT) results in myocardial injury as assessed by changes in high sensitivity cardiac troponin T (hs-cTnT). This will be done by comparing pre-and-post DFT hs-cTnT levels in these patients.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients 18 years and older.
  • Patients who are undergoing elective defibrillation threshold testing of their transvenous ICD or defibrillation threshold testing of the subcutaneous ICD at the time of implantation.

Exclusion Criteria: 

  • Patients under age 18 years old.
  • Patients with myocardial infarction, coronary artery bypass grafting or any invasive cardiac procedure in the previous six weeks.
  • Pregnant patients.
  • Patients who cannot provide informed consent because of cognitive dysfunction.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Ronstan Lobo, M.B., B.Ch., B.A.O.

Open for enrollment

Contact information:

Ronstan Lobo M.B., B.Ch., B.A.O.

(507)284-4442

Lobo.Ronstan@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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