A Study to Evaluate NT-proBNP Levels in the Prediction of Intrapartum and Postpartum Events in Adult Congenital Heart Disease Patients


About this study

The purpose of this study is to characterize the relationship between NT-proBNP levels obtained at time of admission for delivery and subsequent cardiovascular events in ACHD patients, and to describe normative values for NT-proBNP at time of admission for delivery in an uncomplicated obstetric population.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Pregnancy with congenital heart disease (study group) or without congenital heart disease (control group).

Exclusion Criteria: 

  • Non-pregnant patients.
  • Non-English-speaking patients.
  • Maternal age < 18 years or > 50 years old.
  • Patients with hypertensive complications of pregnancy.
  • Maternal peripartum cardiomyopathy.
  • Multiple gestation.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Carl Rose, M.D.

Open for enrollment

Contact information:

Maureen Lemens C.C.R.C.



More information


Publications are currently not available