A Study to Assess Multiparametric MR Elastography (MRE) in Diagnosing and Monitoring Cirrhosis or Hepatocellular Carcinoma (HCC) Patients


About this study

The primary purpose of this study is to is to develop an advanced multiparametric liver magnetic resonance elastography (MRE) imaging technology for early identification of hepatocellular carcinoma (HCC) involvement, differentiation, and risks of microvascular invasion.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 years old (HCC is rare in US children).
  • Diagnosis of HCC with cross-sectional imaging or histology.
  • 3D MRE of the liver was performed within 1 month of diagnosis.

Exclusion Criteria: 

  • History of secondary hepatic malignancy.
  • Any medical condition that, in the opinion of the Principal Investigators, would serve as exclusion criteria.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Douglas Simonetto, M.D.

Open for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

More information


Publications are currently not available

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

International patient clinical studies questions