A Study to Compare Somatostatin Analogues with Perioperative Antibiotics versus Prolonged Antibiotics


About this study

The purpose of this study is to to determine the individual treatment effect of somatostatin and whether duration of antibiotic therapy coupled with octreotide provides improved outcomes after pancreaticoduodenectomy. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients undergoing a Whipple procedure for various diagnoses (neuroendocrine tumors, adenocarcinoma, benign cystic neoplasms, duodenal and ampullary malignancies, etc.) who are deemed intermediate-high risk as per our institutional protocol as shown above.
  • Patients > 18 years of age with the above mentioned diagnoses.

Exclusion Criteria:

  • Negligible and low risk patients.
  • All patients undergoing arterial resection.
  • Age < 18 years old.
  • Currently pregnant.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Michael Kendrick, M.D.

Open for enrollment

Contact information:

Kimberly Nuhanovic CCRP



More information


Publications are currently not available

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

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