A Study of Endovascular Biopsy and Endothelial Cell Gene Analysis in Endovascular Procedures


About this study

The purpose of this study is to determine endothelial gene expression from guidewire biopsy during clinically indicated endovascular procedures. The genetic analysis will be measured against clinical outcomes and treatment response (response to non-coated and drug-coated technologies and different embolic agents depending on the procedure).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults patients and children 5-17 years of age who undergo clininically indicated endovascular arterial or venous procedures by Interventional Radiology will be recruited.

Exclusion Criteria:

  • Adult patients who are unable to provide informed consent.

Eligibility last updated 8/17/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Sanjay Misra, M.D.

Open for enrollment

Contact information:

Sanjay Misra M.D.



More information


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