Pharmacogenetics in Lung Transplant Patients
Tab Title Description
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
- Jacksonville, Florida: 17-008131
Sponsor Protocol Number: 17-008131
About this study
The purpose of this study is to:
- Demonstrate pharmacogenetic variability in the Mayo Clinic Florida lung transplant population.
- Describe patterns in tacrolimus levels in the context of pharmacogenomic profiles
- Use pharmacogenomic data to establish a need for therapeutic drug monitoring in selected other drugs
- Use pharmacogenomic data, in combination with knowledge of drug interactions, to establish sensitivity to tacrolimus dose changes
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
- First time lung transplant recipients at Mayo Clinic Florida that are prescribed Tacrolimus as part of their immunosuppression regimen
- Recipients of a second lung transplant
- Recipients of multiple organ transplants
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
|Mayo Clinic Location
Mayo Clinic principal investigator
Jorge Mallea, M.D.
Closed for enrollment
Publications are currently not available