Real-Time Feedback Training to Improve Gait and Posture in People with Parkinson’s Disease


About this study

This study will investigate the effects of Real-Time Feedback Training and treadmill training to improve gait posture in subjects with Parkinson’s Disease.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Presence of idiopathic PD according to UK brain bank criteria 
  2. Age 50-80 years 
  3. Presence of Unified Parkinson’s Disease Rating Scale (UPDRS) walking and freezing score ≥1 during medication-on state
  4. Stable dose of PD medication for 4 weeks prior to the study
  5. Absence of dementia, defined by Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria, (7) no regular use of assistance gait device such as walker or cane 
  6. No prominent dyskinesia (UPDRS dyskinesia score > 1) 
  7. No on/off fluctuations throughout day 
  8. No frequent falls (UPDRS fall score > 1), no significant postural instability (UPDRS postural stability score > 2), and
  9. No freezing leading to falls that would affect subjects’ safety or compliance with protocol.

Exclusion Criteria:

  1. A candidate will be excluded if they have:
  2. Recent history of unstable heart or lung disease 
  3. Evidence of pregnancy, uncontrolled psychiatric illness, major neurological condition other than PD (e.g., stroke)
  4. Musculoskeletal (e.g., rheumatoid arthritis) or metabolic problems (e.g., diabetes)
  5. A candidate will also be excluded if they have recently participated in any other study involving exercise to improve gait or posture

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Erika Driver-Dunckley, M.D.

Closed for enrollment

More information


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Additional contact information

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