Decreasing Agitation in Patients with Dementia Through the Use of Weighted Blankets


About this study

The purpose of this study is to reduce behaviors and psychotic symptoms of dementia by using a weighted blanket as a non-pharmacological method to decrease agitation and distress in the elderly population.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

- Patients admitted on the inpatient geriatric psychiatry unit, complex interventions
unit, internal medicine service and/or admitted hospice GIP

- Documented diagnosis of dementia or suspected major neurocognitive disorder.

- Presence of agitation/aggression symptoms as defined by a minimum aggression score on
the Cohen-Mansfield Agitation Inventory Short Version (CMAI): Patients must score 3,
4, or 5 on at least one question related to aggression (items 1-4).

- Have a LAR able to sign the consent on behalf of the patient.

Exclusion Criteria:

- Inability to remove blanket;

- Skin burns or open wounds;

- Admitted on 72 hour hold.


Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 3/28/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Maria Lapid, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Monica Walton CCRP


More information


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