A Study to Establish Novel Tumor Models Using Scant Tumor Specimens from Solid Tumor Patients

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 17-003174
    • Scottsdale/Phoenix, Arizona: 17-003174
    Sponsor Protocol Number: 17-003174

About this study

The objective of this research is to determine the feasibility of establishing organoid tumor models using scant solid tumor tissues obtained by image-guided core needle biopsy procedures during routine clinical care. The routine clinical biopsy may be by image-guidance, endoscopic-guidance (e.g., EGD, colonoscopy, bronchoscopy), direct visualization (e.g., skin biopsy) and surgical exploration. Once established, the tumor organoids’ response to anti-cancer agents will be assessed. If proven feasible, this technique can potentially be integrated into routine clinical care of solid tumor patients and help guide the treatment of the donor patient in the clinic.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Patient must have cytologically or histologically confirmed solid tumor.
  • Should be undergoing biopsy procedure as part of routine clinical care.
  • Age 18 years and above.

Exclusion Criteria: 

  • Patients who will be undergoing fine-needle aspiration (FNA) biopsy are excluded.
  • Woman known to be pregnant is excluded.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Wen Wee Ma, M.B.B.S.

Open for enrollment

Contact information:

Temperance Scheffler Hanson R.N.

(507)293-0816

Scheffler.Temperance@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Wen Wee Ma, M.B.B.S.

Open for enrollment

Contact information:

Laurie Mihalik

(480)342-3256

Mihalik.Laurie@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

International patient clinical studies questions