Collection of Tissue and Blood in Patients with Allergic and Immunologic Disorders


About this study

Allergic and immunologic disorders are very common but some are very poorly understood. Numerous studies of the epidemiology, characteristics, diagnosis and treatment of these disorders are urgently needed to identify and optimally treat affected patients. Though numerous challenges impact the progress of research in this area, specimens are needed to test new hypotheses and methodologies.  We aim to create a registry and biorepository of tissue and fluid specimens for future studies.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria: 

  • All patients with a suspected allergic or confirmed immunologic disorder undergoing endoscopy for symptoms of esophageal dysfunction between the ages of 0 to 80 will be eligible for participation in this study.

Exclusion Criteria:

  • Previous esophageal congenital disorders such as tracheal esophageal fistula and esophageal atresia.
  • Gastrointestinal bleeding or active anticoagulation.
  • Known esophageal cancer.
  • Prior esophageal surgery.
  • Known esophageal varices.
  • Medical instability or multiple comorbidities precluding enrollment in the clinical opinion of the endoscopist.
  • For the optional esophageal string test, inability to swallow a capsule or gelatin allergy are exclusion criteria.

Eligibility last updated 9/1/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Benjamin Wright, M.D.

Open for enrollment

Contact information:

Yasmin Bernal C.Ph.T.

(480) 574-2440

More information


Publications are currently not available