A Study to Determine the Tradeoffs between CT Image Quality and Patient Radiation Dose


About this study

The purpose of this study is to determine the tradeoffs between CT image quality and patient radiation dose in a way that moves beyond current simple models (e.g. standard deviation and CTDIvol) by investigating the relationships between task-based metrics of image quality, observer performance, patient size, and patient dose.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients who had clinically-indicated CT scans, and Minnesota authorization for research use of medical records and images (as applicable).

Exclusion Criteria: 

  • Patient cases not meeting inclusion criteria will be excluded.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Cynthia McCollough, Ph.D.

Contact us for the latest status

Contact information:

Dong Chen M.D., Ph.D.

(507) 538-8002


More information


Publications are currently not available