Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.See eligibility criteria
- Adult patients (age 18 or older) being prescribed any treatment for PBC (initial or subsequent) outside of a clinical trial. A diagnosis of PBC requires the presence of at least 2 of the following 3 criteria: a. Unexplained elevation of serum alkaline phosphatase b. Positive anti-mitochondrial antibody at a titer ≥ 1:40 c. Liver biopsy showing both: i. compatible destructive nonsuppurative cholangitis and ii. destruction of interlobular bile ducts
- Inability to provide written informed consent
- Current or planned participation in another registry or study where PBC treatment outcomes are reported, except where approved or conducted as an adjunct project of TARGET-PBC.
- Participation in a clinical trial at the time of enrollment in TARGET-PBC. Patient may enroll in TARGET-PBC once their participation in the clinical trial has ended.