Exploring Duodenal Biopsies as a Biomarker of Pancreatic Cancer

Overview

About this study

To determine whether the microbiome, metagenome and metabolome of the tissue of the second portion of duodenum of patients with pancreatic cancer are different from that of patients with benign conditions not affecting the pancreas.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Subject and Control Inclusion Criteria

  • Adults aged 18 and older
  • Patients scheduled to undergo an endoscopy.
  • Patients with indications for endoscopy due to known of suspected Pancreatic Cancer but no other GI tract cancer, polyps and who are scheduled for endoscopy as part of their medical evaluation.

Subject and Control Exclusion Criteria

  • Individuals who do not comprehend English (i.e. participants must be able to read and sign a consent form without the assistance of an interpreter.)
  • Individuals who are unable to sign consent (e.g., mentally challenged, those declared legally incompetent)
  • Individuals regarded as belonging to a vulnerable population (e.g., prisoners)
  • Patients diagnosed with Helicobacter pylori infection
  • Patients with suspected GI tract cancer other than pancreatic cancer
  • Antibiotic use within the past 3 months
  • Any surgical procedure on the GI tract
  • Age <18 or vulnerable adults
  • Presence of bleeding disorders
  • Use of anti-coagulants

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Mark Truty, M.D., M.S.

Closed for enrollment

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

International patient clinical studies questions