Justifying Patellar Instability Treatment by Early Results


About this study

The purpose of this study is to compare the safety and efficacy of (1) non-operative treatment, (2) isolated Medial Patellofemoral Ligament (MPFL) reconstruction, and (3) ‘à la carte’ surgical approach to treat patellar instability. Enrollment will take place over one year at 12 sports centers. Outcomes would be assessed at 6, 12, 24 and 60 months, including assessment of function, activity level, quality of life and complications.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Documented episode of patellar dislocation (first episode or recurrent episodes)
  • Age: 10-25 years
  • Hypermobility instability (eg Ehlers Danlos Syndrome)
  • Habitual patellar dislocation

Exclusion Criteria:

  • Neuromuscular disorder (eg: Cerebral Palsy)
  • Congenital or permanent patellar dislocation
  • Multiple ligamentous injury (Knee dislocation)
  • Significant other health conditions or developmental delays

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Daniel Saris, M.D., Ph.D.

Closed for enrollment

Contact information:

Jennifer Krogman

(507) 538-3562


More information


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