A Study Comparing Carotid Revascularization Endarterectomy Versus Stenting

Overview

About this study

The purpose of this study is to compare the relatively new procedure of stent-assisted carotid angioplasty to the traditional and accepted surgical approach of carotid endarterectomy for the treatment of carotid artery stenosis to prevent recurrent strokes in those patients who have had a TIA (transient ischemic attack) or a mild stroke within the past 6 months (symptomatic) and in those patients who have not had any symptoms within the past 6 months (asymptomatic).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Symptomatic with recent neurological events (TIA or non-disabling stroke) and an associated carotid stenosis  ≥ 50% by angiography or ≥ 70% by ultrasound or ≥70% by Computed Tomography Angiography or Magnetic Resonance Angiography 
  • Asymptomatic with no recent (in the last 6 months) neurological events referable to the study with artery and carotid stenosis (patients with symptoms beyond 180 days are considered asymptomatic) ≥ 60% by angiography or ≥ 70% by ultrasound or ≥ 80% by CTA or MRA

Exclusion Criteria

  • Conditions that
    • Interfere with the evaluation of endpoints
    • Are known to interfere with the completion of CEA or CAS
    • Affect the likelihood of survival for the 4 year study period
  • Chronic atrial fibrillation and/or anti-coagulation or episodic atrial fibrillation within the last 6 months

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Jacksonville, Fla.

Mayo Clinic principal investigator

Albert Hakaim, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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