Collection of Discarded Cerebrospinal Fluid for Research Purposes


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-000747
    Sponsor Protocol Number: 16-000747

About this study

The purpose of this study is to collect and store cerebrospinal fluid (CSF)from patients with normal CSF.  This stored CSF will be used in the future as a culture media to better understand how therapeutic cells delivered into the CSF will behave. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Age >18 years old, men & women
  • Undergoing lumbar puncture for clinical purposes (e.g. normal pressure hydrocephalus or pseudotumor cerebri)
  • High pre-test probability of normal CSF parameters (glucose, protein, WBC, RBCs)
  • CSF protein <60 mg/dL
  • CSF glucose, nucleated cells and red blood cells within normal limits
  • All other CSF testing within normal limits

Exclusion Criteria:

  • Pregnancy

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Nathan Staff, M.D., Ph.D.

Open for enrollment

Contact information:

Michelle Turner