Microvascular Function and Exercise Training in Postmenopausal Women


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 15-009659
    Sponsor Protocol Number: 15-009659

About this study

Blood pressure rises in postmenopausal (PM) women and may be caused by widespread microvascular vasodilator dysfunction in conjunction with increased efferent sympathetic vasoconstrictor nerve activity. The goal of this study is to measure the effects of regular physical activity on vasodilator effects of acute administration of estrogen in postmenopausal women.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Young sedentary premenopausal women, 18-35 years of age
  • Sedentary PM women, 50-65 years of age
  • Young exercise trained premenopausal women, 18-35 years of age.
  • Exercise trained PM women, 50-65 years of age
  • All inclusion/exclusion criteria will be at the discretion of the Investigator.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

More information


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Study Results Summary

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Supplemental Study Information

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Additional contact information

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