Prospective Study of Adrenal Disorders: Clinical Registry, Imaging Analysis and Biomaterial Collection

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 13-005838
    Sponsor Protocol Number: 13-005838

About this study

The purpose of this research is to follow people with adrenal disorders in order to make conclusions about the natural history of a particular adrenal disease as well as effect of various therapies and interventions decided on by you and your medical team. In addition, we will collect biomaterial from you at times you are being evaluated which will be used to discover novel biomarkers which can potentially improve the accuracy of current diagnostic tests and affect the management of patients with adrenal disorders. We will also include a control group (without known adrenal disease) to compare to the volunteers with adrenal disorders.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:            

  • Patients with:

    • adrenal mass of any etiology

    • steroidogenesis defect ( examples: 21OH congenital hyperplasia, 11 beta congenital hyperplasia)

    • primary or secondary adrenal insufficiency

    • Cushing’s syndrome due to pituitary or ectopic ACTH production

    • Inadequate glucocorticoid, mineralocorticoid or androgen axis of unknown etiology

    • Healthy individuals

    • Patients seen for problems other than mentioned above and willing to contribute biomaterial

  • Age 18-99 years

    Exclusion Criteria:           

  • Age <18 years

     

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Irina Bancos, M.D.

Open for enrollment

Contact information:

Melinda Thomas

(507)293-6628

Thomas.Melinda@mayo.edu