Left Ventricular Remodeling and Echocardiographic Predictors of Mortality in Severe Aortic Stenosis
Tab Title Description
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
- Rochester, Minnesota: 16-003115
Sponsor Protocol Number: 16-003115
About this study
The purpose of this study is to compare 3D measurements to conventional 2D measurements of left ventricular size and mass, left ventricular systolic function, and left ventricular diastolic function in patients with severe aortic stenosis and determine whether there are significant differences in remodeling between men and women and in those with and without a history of hypertension. The study will also aim to identify echocardiographic markers associated with NYHA symptom class, risk of atrial fibrillation, the need for aortic valve operation, or cardiac death or persistent heart failure after aortic valve replacement for severe aortic stenosis.
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
- Adults ≥ 18 years of age undergoing aortic valve replacement
- Severe aortic stenosis
- Currently in sinus rhythm
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
|Mayo Clinic Location
Mayo Clinic principal investigator
Jeremy Thaden, M.D.
Closed for enrollment
Publications are currently not available