A Study to Increase Understanding About Pancreatic Cancer Genetics and Response to Drug Therapy
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 14-006794
Sponsor Protocol Number: 14-006794
About this study
The purpose of this study is to learn more about pancreatic cancer genetics in association with response to drug therapy. Pancreatic cancer has identifiable genetic (DNA) changes, yet for many it is not known whether these affect response to cancer drugs.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Has a diagnosis of Pancreatic cancer, with at least 1 site accessible for biopsy
- Willing to undergo research biopsy for creation of xenograft
- Ability to provide written consent
- Genetic variant on screening test that affects DNA repair, or a personal/family history of cancer strongly suggestive of such a variant
Exclusion Criteria
- Must have no contraindications to biopsy (e.g. bleeding disorders, or a need for anticoagulation that cannot be safely held or bridged)
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Robert McWilliams, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available