A Study of Carotid MRI/MRA to Evaluate the Amount of Plaque in the Arteries of Patients Taking Cholesterol Lowering Medication
Tab Title Description
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
- Rochester, Minnesota: 16-004060
Sponsor Protocol Number: 16-004060
About this study
The purpose of this study is to assess if it is possible to use a carotid MRI/MRA to see if cholesterol lowering medication is causing a reduction in the amount of plaque in the arteries.
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
- Adults starting PCSK9 inhibitors for treatment of hypercholesterolemia
- Able to come back to Mayo for follow-up imaging at 3-9 months and 12-18 months following initiation of therapy
- Pregnant or nursing
- Are not on PCSK9 inhibitors
- Has renal failure
- GFR < 30
- Has claustrophobia
- Has gadolinium allergy
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
|Mayo Clinic Location
Mayo Clinic principal investigator
John Huston, M.D.
Closed for enrollment
Publications are currently not available