A Study of the Effects of Synovial (Joint Lubricating) Fluid on the Development of Osteoarthritis


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 14-000440
    Sponsor Protocol Number: 14-000440

About this study

The purpose of this study is to learn the effects of synovial fluid, a clear thick joint lubricant, on joint cartilage tissue and the development of osteoarthritis

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Patients undergoing elective knee replacement or knee drainage
  • Age: >18


Exclusion Criteria 

  • Any prior history of oncology in limb
  • Prior knee surgery

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Andre van Wijnen, Ph.D.

Open for enrollment

Contact information:

Andre van Wijnen Ph.D.