A Study of the Cardio-Ankle Vascular Index as it Relates to Indicators of Left Ventricle Structure and Function


About this study

The purpose of the study is to test whether cardio-ankle vascular index, a measure of arterial stiffness that can be obtained in the office setting, is associated with cardiac function and structure as assessed by echocardiography.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Age 18-80 years
  • Patients referred for transthoracic echocardiography
  • Able to provide informed consent


Exclusion Criteria 

  • Known cardiovascular disease
  • Known to have structural heart disease, e.g. valvular heart disease, cardiomyopathy etc
  • Brachial edema or brachial with bleeding tendency (when renal failure or serious liver disease is suspected)
  • Possible blood congestion that may cause thrombus (blunt lung anamnesis or thromboarthritis)
  • Possible blood congestion which may cause peripheral circulation obstruction (Raynaud’s disease or angitis)
  • Artificial dialysis shunts in their brachial artery
  • Pregnancy

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Iftikhar Kullo, M.D.

Closed for enrollment

More information


Publications are currently not available

Additional contact information

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