A Study for RNA (Genetic) Analysis in Adult Patients with Eosinophilic Esophagitis


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-000338
    Sponsor Protocol Number: 16-000338

About this study

The purpose of this study is to perform RNA (genetic) sequencing on biopsies taken from the esophagus of adult patients who have active eosinophilic esophagitis, and look for potential therapeutic targets.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Adult patients older than 18 years
  • There will be three equal sized study groups
    • Normal controls
    • Patients with active Eosinophilic Esophagitis
    • Patients with active Eosinophilic Esophagitis who have been treated with steroids with improvement in symptoms  
  • Biopsies will be taken from mid and distal esophagus from those patients with Eosinophilic Esophagitis

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

David Katzka, M.D.

Closed for enrollment

Additional contact information

Non-cancer trials contact form

Phone: 800-664-4542 (toll-free)

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