A Study of Immune Cell Abnormalities Found in Individual Patients who have Type 1 Diabetes and are Waiting for Pancreas or Pancreas/Kidney Transplant Surgery


About this study

The purpose of this study is to measure and characterize specific immune cell abnormalities found in patients who have type 1 diabetes and may or may not be on the waiting list for either a pancreas alone or a pancreas and kidney transplant.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria  

  • Has type 1 diabetes and is on the waiting list for
    • Simultaneous pancreas and kidney transplantation
    • Pancreas transplantation alone
  • Is listed for kidney transplantation without immune mediated disease 
  • Could be an age and gender matched control for pancreas and kidney transplant group

Exclusion Criteria

  • Has factors confounding interpretation of evaluation such as 
    • Previous solid organ or stem cell transplantation 
    • Current acute or chronic infection of any kind 
    • Current or prior immunosuppressive medication use  
    • Any other condition that in the opinion of the study team would confound study end points

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Yogish Kudva, M.B.B.S.

Open for enrollment

Contact information:

Vikash Dadlani M.B.B.S.

(507) 284-1920


More information


Publications are currently not available