A Study to Determine the Effects of Blocking the Receptors of GLP-1 on Appetite after Bariatric Surgery


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 16-001973
    NCT ID: NCT02779075
    Sponsor Protocol Number: 16-001973

About this study

The purpose of this study is to determine the effects of blocking the receptors of the Glucagon-like Peptide-1 (GLP-1) hormone after different types of bariatric surgery on the regulation of food intake and appetite control.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Has undergone either sleeve gastrectomy or Roux-en-Y Gastric Bypass surgery within prior 2 years
  • Healthy, with no active systemic illness

Exclusion Criteria

  • Pregnancy
  • Functional or organic bowel symptoms
  • Systemic illness
  • Diabetes
  • Bariatric surgery > 2 years

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Adrian Vella, M.D.

Open for enrollment

Contact information:

Paula Giesler R.N.