A Study of 3D Doppler Echocardiography for More Accurate Measurement of Mitral Valve Regurgitation


About this study

The purpose of this study is to compare the value and practicality of using 3D color doppler echocardiography of the vena contracta area versus the standard 2D method when needing accurate measurement of mitral valve regurgitation.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.


Inclusion Criteria

  • Native mitral valve regurgitation (mild or greater) or mitral paravalvular leak (any degree of regurgitation)
  • Undergoing transesophageal echocardiography, with or without mitral paravalvular leak closure or percutaneous repair of the mitral valve (e.g. MitraClip) for clinical indications


Exclusion Criteria 

  • Inadequate image quality
  • Age <18 years

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Charles Bruce, M.D.

Closed for enrollment

More information


Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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