A Study of Advanced MR Imaging in Sarcoma Patients

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 15-005622
    NCT ID: NCT02705391
    Sponsor Protocol Number: 15-005622

About this study

The purpose of this study is to compare the clinical application of two emerging magnetic resonance (MR) imaging modalities which Mayo Clinic has the technical capability of using, by adding them at the same time that standard imaging is done for patients receiving treatment for Ewing Sarcoma , Rhabdomyosarcoma and soft tissue sarcoma.  

 

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Age ≥ 7 years
  • Histological confirmation of newly diagnosed localized or newly diagnosed with metastatic Ewing Sarcoma, Rhabdomyosarcoma or Soft tissue Sarcoma
  • Tumors > 5 cm in diameter
  • Planning to receive RT or surgery with or without adjuvant radiotherapy (RT) at Mayo Clinic Rochester
  • Provide informed written consent if ≥ 18 years. If < 18 years, provide informed written assent and parent or legal guardian provide informed written consent
  • Patients must have measurable disease as defined in Section 11.0
  • Willingness to participate in mandatory imaging studies at Mayo Clinic Rochester
  • Baseline MRE information deemed as acceptable for assessment
  • Baseline perfusion MRI deemed as acceptable for assessment

Exclusion Criteria:

  • Co-morbid conditions that would result in expected survival to be less than 5 years

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Deanna Pafundi, Ph.D.

Open for enrollment

Contact information:

Sarah James M.D., Ph.D.

(715)464-8148

James.Sarah1@mayo.edu

Additional contact information

Cancer-related trials contact form

Phone: 855-776-0015 (toll-free)

International patient clinical studies questions