A Study of Body Changes When Placed in High Challenge Stress


About this study

The purpose of this study is to better understand the demands on and responses of the human body to participation in extreme events, exposure to extreme environments or exposure to an intervention or treatment.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • up to 200 subjects for the study
  • specific data sets of 15-20 individuals within a given type of activity or event
  • both males and females
  • between the ages of 18-80 years
  • individuals who have chosen to participate in a particular expedition, athletic event, clinical research study, or live in an extreme environment, independent of the present study
  • Subjects will have complete control over their willingness to participate in the study and control over whether or not to continue with the event or exposure regardless of the impact on the study
  • Written consent will be obtained from all subjects prior to participation

Exclusion Criteria

  • based on the requirements and exclusion criteria of the exposure the individual is receiving
  • will also include pregnancy

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Bruce Johnson, Ph.D.

Open for enrollment

Contact information:

Briana Ziegler



More information


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