A Study of the Effects of Menopause and Exercise on Blood Flow in Healthy Women


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 14-001327
    Sponsor Protocol Number: 14-001327

About this study

The purpose of this study is to see if age, sex hormones and regular exercise impact blood flow in healthy women.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • young premenopausal women ages of 18 and 35 years old or non-surgically induced post-menopausal women ages 45-75
  • non-smokers.
  • premenopausal subjects will undergo a urine pregnancy test, must be negative to participate


Exclusion Criteria

  • Any history or evidence of hepatic, renal, or hematological disease
  • Peripheral vascular disease
  • Stroke/neurovascular disease
  • Diabetes
  • Dyslipoproteinemia
  • Uncontrolled hypertension
  • Lung disease, or arthritis affecting ability to exercise
  • A body mass index >30 kg/m2
  • If taking medication that alters autonomic or vascular function (e.g., tricyclic antidepressants, α-blockers, β-blockers, etc.)
  • Subjects who are breastfeeding will be excluded.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

Additional contact information

Non-cancer trials contact form

Phone: 800-664-4542 (toll-free)

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