A Study Identifying Blood Serum Markers of the Immune System Affecting Different Features of Chronic Rhinosinusitis
Tab Title Description
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
- Rochester, Minnesota: 14-001630
Sponsor Protocol Number: 14-001630
About this study
The purpose of this study is to find out what immune system processes cause the chronic inflammation that happens with chronic rhinosinusitis (CRS) and if there are different immune system pathways involved among CRS patients.
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
- Age 18 years and older.
- Both males and females
- Meet clinical definition of CRS
- nasal obstruction
- facial congestion
- facial pain-pressure-fullness
- decrease in sense of smell
- Presence or absence of nasal polyps as evidenced by a CT scan or rhinoscopy
Exclusion criteria (history suggestive or presence of)
- Cystic fibrosis
- Primary ciliary dyskinesia
- Primary immune deficiency disorder
- Pregnant at time of clinic visit
- Cigarette smoking in the last 6 months
- SNOT-22 scores greater than 21 (to exclude those currently in exacerbation)
- Oral corticosteroids in the past 2 weeks before visit
- Intramuscular corticosteroids in the past 6 weeks before visit
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
Publications are currently not available