A Prospective Registry for Patients with REM Sleep Behavior Disorder and Polysomnographic REM Sleep without Atonia and Controls


About this study

The purpose of this study is to follow patients with REM sleep behavior disorder (RBD) over time and learn which types of RBD patients may be at risk of developing other diseases.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Children aged 12-17.
  • Adults of all ages.
  • Patients with probable REM Behavior Disorder (RBD), RBD, and REM Sleep Without Atonia (RSWA) or Parkinson’s disease (PD), parkinsonism, mild cognitive impairment, dementia with Lewy bodies, multiple system atrophy, and pure autonomic failure seen in the Mayo Center for Sleep Medicine or Mayo Clinic Department of Neurology.
  • Control subjects matched for age and gender with primary snoring or obstructive sleep apnea (matched for AHI of RBD/RSWA) without polysomnographic RSWA will also participate.

Exclusion Criteria:

  • Children less than 12 years of age.
  • Those with developmental delay.

Eligibility last updated 12/27/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Erik St. Louis, M.D.

Open for enrollment

Contact information:

Emma Strainis

(507) 266-6627


More information


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