Intra-Articular Dexamethasone to Prevent Post-Traumatic Osteoarthritis: A Pilot Study
Tab Title Description
Describes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
- Rochester, Minnesota: 14-004033
NCT ID: NCT02318433
Sponsor Protocol Number: 14-004033
About this study
The primary aim of the study is to see if a single wrist injection (intra-articular) of dexamethasone at the time of treatment will reduce the incidence of early-onset of post traumatic osteoarthritis.
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
- Unstable distal radius fracture.
- Fracture type AO B1, B2, B3, C1, or C2 or C3.
- 18-65 years old.
- Understand and read English.
- Community dwelling (not in assisted living or NH).
- Open or bilateral DRF.
- Associated upper extremity fracture or ligament injuries requiring casting or surgical repair at the time of DRF fixation.
- Multitrauma pts.
- Greater than 2 weeks post injury.
- Neurologic disorders affecting the hand, wrist or arm.
- History of dementia, Alzheimers or other neurologic dx.
- Substance abuse.
- Pathologic fractures.
- Known pregnancy.
- Radiocarpal joint arthritis.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
|Mayo Clinic Location
Mayo Clinic principal investigator
Sanjeev Kakar, M.D.
Closed for enrollment
Publications are currently not available