Publications

  1. Day SE, Coletta RL, Kim JY, Garcia LA, Campbell LE, Benjamin TR, Roust LR, De Filippis EA, Mandarino LJ, Coletta DK. Potential epigenetic biomarkers of obesity-related insulin resistance in human whole-blood. Epigenetics. 2017 Apr 03; 12: (4)254-263.
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  2. Day SE, Garcia LA, Coletta RL, Campbell LE, Benjamin TR, De Filippis EA, Madura JA 2nd, Mandarino LJ, Roust LR, Coletta DK. Alterations of sorbin and SH3 domain containing 3 (SORBS3) in human skeletal muscle following Roux-en-Y gastric bypass surgery. Clin Epigenetics. 2017; 9:96 Epub 2017 Sept 02
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  3. Campbell LE, Langlais PR, Day SE, Coletta RL, Benjamin TR, De Filippis EA, Madura JA 2nd, Mandarino LJ, Roust LR, Coletta DK. Identification of Novel Changes in Human Skeletal Muscle Proteome After Roux-en-Y Gastric Bypass Surgery. Diabetes. 2016 Sep; 65 (9):2724-31 Epub 2016 May 10
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  4. Shaibi G, Singh D, De Filippis EA, Hernandez V, Rosenfeld B, Otu E, Montes de Oca G, Levey S, Radecki Breitkopf C, Sharp R, Olson J, Cerhan J, Thibodeau S, Winkler E, Mandarino L. The Sangre Por Salud Biobank: Facilitating Genetic Research in an Underrepresented Latino Community. Public Health Genomics. 2016 Jul 5;
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  5. Day SE, Coletta RL, Kim JY, Campbell LE, Benjamin TR, Roust LR, De Filippis EA, Dinu V, Shaibi GQ, Mandarino LJ, Coletta DK. Next-generation sequencing methylation profiling of subjects with obesity identifies novel gene changes. Clin Epigenetics. 2016; 8:77.
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  6. Tran L, Hanavan PD, Campbell LE, De Filippis E, Lake DF, Coletta DK, Roust LR, Mandarino LJ, Carroll CC, Katsanos CS. Prolonged Exposure of Primary Human Muscle Cells to Plasma Fatty Acids Associated with Obese Phenotype Induces Persistent Suppression of Muscle Mitochondrial ATP Synthase beta Subunit. PLoS One. 2016; 11: (8)e0160057.
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  7. De Filippis EA, Sabet A, Sun MR, Garber JR. Pemberton's sign: explained nearly 70 years later. J Clin Endocrinol Metab. 2014 Jun; 99(6):1949-54. Epub 2014 Mar 19.
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  8. Langlais P, Yi Z, Finlayson J, Luo M, Mapes R, De Filippis E, Meyer C, Plummer E, Tongchinsub P, Mattern M, Mandarino LJ. Global IRS-1 phosphorylation analysis in insulin resistance. Diabetologia. 2011 Nov; 54(11):2878-89. Epub 2011 Aug 18.
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  9. Holmes RM, Yi Z, De Filippis E, Berria R, Shahani S, Sathyanarayana P, Sherman V, Fujiwara K, Meyer C, Christ-Roberts C, Hwang H, Finlayson J, Dong LQ, Mandarino LJ, Bajaj M. Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling. Diabetologia. 2011 Aug; 54(8):2122-31. Epub 2011 May 12.
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  10. Lefort N, Glancy B, Bowen B, Willis WT, Bailowitz Z, De Filippis EA, Brophy C, Meyer C, Hojlund K, Yi Z, Mandarino LJ. Increased reactive oxygen species production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1B protein despite normal mitochondrial respiration in insulin-resistant human skeletal muscle. Diabetes. 2010 Oct; 59(10):2444-52. Epub 2010 Aug 03.
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  11. Hwang H, Bowen BP, Lefort N, Flynn CR, De Filippis EA, Roberts C, Smoke CC, Meyer C, Hojlund K, Yi Z, Mandarino LJ. Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes. Diabetes. 2010 Jan; 59(1):33-42. Epub 2009 Oct 15.
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  12. Lefort N, Yi Z, Bowen B, Glancy B, De Filippis EA, Mapes R, Hwang H, Flynn CR, Willis WT, Civitarese A, Hojlund K, Mandarino LJ. Proteome profile of functional mitochondria from human skeletal muscle using one-dimensional gel electrophoresis and HPLC-ESI-MS/MS. J Proteomics. 2009 Aug 20; 72(6):1046-60. Epub 2009 Jun 28.
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  13. Yi Z, Bowen BP, Hwang H, Jenkinson CP, Coletta DK, Lefort N, Bajaj M, Kashyap S, Berria R, De Filippis EA, Mandarino LJ. Global relationship between the proteome and transcriptome of human skeletal muscle. J Proteome Res. 2008 Aug; 7(8):3230-41. Epub 2008 Jul 10.
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  14. De Filippis E, Alvarez G, Berria R, Cusi K, Everman S, Meyer C, Mandarino LJ. Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear-encoded mitochondrial genes to exercise. Am J Physiol Endocrinol Metab. 2008 Mar; 294(3):E607-14. Epub 2008 Jan 08.
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  15. Formoso G, De Filippis EA, Michetti N, Di Fulvio P, Pandolfi A, Bucciarelli T, Ciabattoni G, Nicolucci A, Davi G, Consoli A. Decreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects. Diabetes Metab Res Rev. 2008 Mar-Apr; 24: (3)231-7.
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  16. Pandolfi A, De Filippis EA. Chronic hyperglicemia and nitric oxide bioavailability play a pivotal role in pro-atherogenic vascular modifications. Genes Nutr. 2007 Nov; 2(2):195-208. Epub 2007 Oct 17.
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  17. Luo M, Langlais P, Yi Z, Lefort N, De Filippis EA, Hwang H, Christ-Roberts CY, Mandarino LJ. Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling. Endocrinology. 2007 Oct; 148(10):4895-905. Epub 2007 Jul 19.
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  18. Berria R, Glass L, Mahankali A, Miyazaki Y, Monroy A, De Filippis E, Cusi K, Cersosimo E, Defronzo RA, Gastaldelli A. Reduction in hematocrit and hemoglobin following pioglitazone treatment is not hemodilutional in Type II diabetes mellitus. Clin Pharmacol Ther. 2007 Sep; 82: (3)275-81.
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  19. Yi Z, Langlais P, De Filippis EA, Luo M, Flynn CR, Schroeder S, Weintraub ST, Mapes R, Mandarino LJ. Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle. Diabetes. 2007 Jun; 56(6):1508-16. Epub 2007 Mar 14.
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  20. De Filippis E, Cusi K, Ocampo G, Berria R, Buck S, Consoli A, Mandarino LJ. Exercise-induced improvement in vasodilatory function accompanies increased insulin sensitivity in obesity and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2006 Dec; 91(12):4903-10. Epub 2006 Oct 03.
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  21. Triplitt C, Glass L, Miyazaki Y, Wajcberg E, Gastaldelli A, De Filippis E, Cersosimo E, DeFronzo RA. Comparison of glargine insulin versus rosiglitazone addition in poorly controlled type 2 diabetic patients on metformin plus sulfonylurea. Diabetes Care. 2006 Nov; 29: (11)2371-7.
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  22. Berria R, Gastaldelli A, Lucidi S, Belfort R, De Filippis E, Easton C, Brytzki R, Cusi K, Jovanovic L, DeFronzo R. Reduction in hematocrit level after pioglitazone treatment is correlated with decreased plasma free testosterone level, not hemodilution, in women with polycystic ovary syndrome. Clin Pharmacol Ther. 2006 Aug; 80: (2)105-14.
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  23. Maddux BA, Chan A, De Filippis EA, Mandarino LJ, Goldfine ID. IGF-binding protein-1 levels are related to insulin-mediated glucose disposal and are a potential serum marker of insulin resistance. Diabetes Care. 2006 Jul; 29(7):1535-7.
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  24. Berria R, Wang L, Richardson DK, Finlayson J, Belfort R, Pratipanawatr T, De Filippis EA, Kashyap S, Mandarino LJ. Increased collagen content in insulin-resistant skeletal muscle. Am J Physiol Endocrinol Metab. 2006 Mar; 290(3):E560-5. Epub 2005 Oct 25.
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  25. Miyazaki Y, De Filippis E, Wajcberg E, Glass L, Triplitt C, Cersosimo E, Mandarino LJ, DeFronzo R. Predictors of improved glycemic control with thiazolidinediones therapy in type 2 diabetic patients: a practical approach for the primary care physician. British J of Diabetes and Cardiovasc Disease. 2005; 5(1):28-35.
  26. Federici M, Pandolfi A, De Filippis EA, Pellegrini G, Menghini R, Lauro D, Cardellini M, Romano M, Sesti G, Lauro R, Consoli A. G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells. Circulation. 2004 Jan 27; 109: (3)399-405.
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  27. Pandolfi A, Giaccari A, Cilli C, Alberta MM, Morviducci L, De Filippis EA, Buongiorno A, Pellegrini G, Capani F, Consoli A. Acute hyperglycemia and acute hyperinsulinemia decrease plasma fibrinolytic activity and increase plasminogen activator inhibitor type 1 in the rat. Acta Diabetol. 2001; 38: (2)71-6.
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