Publications

  1. Bhattarai Y, Schmidt BA, Linden DR, Larson ED, Grover M, Beyder A, Farrugia G, Kashyap PC. Human-derived gut microbiota modulates colonic secretion in mice by regulating 5-HT3 receptor expression via acetate production. Am J Physiol Gastrointest Liver Physiol 2017 Jul 01; 313 (1):G80-G87 Epub 2017 Apr 13
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  2. Khanna S, Vazquez-Baeza Y, Gonzalez A, Weiss S, Schmidt B, Muniz-Pedrogo DA, Rainey JF 3rd, Kammer P, Nelson H, Sadowsky M, Khoruts A, Farrugia SL, Knight R, Pardi DS, Kashyap PC. Changes in microbial ecology after fecal microbiota transplantation for recurrent C. difficile infection affected by underlying inflammatory bowel disease. Microbiome 2017 May 15; 5 (1):55
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  3. Barnes AMT, Dale JL, Chen Y, Manias DA, Greenwood Quaintance KE, Karau MK, Kashyap PC, Patel R, Wells CL, Dunny GM. Enterococcus faecalis readily colonizes the entire gastrointestinal tract and forms biofilms in a germ-free mouse model. Virulence 2017 Apr 03; 8 (3):282-296 Epub 2016 Aug 25
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  4. Touw K, Ringus DL, Hubert N, Wang Y, Leone VA, Nadimpalli A, Theriault BR, Huang YE, Tune JD, Herring PB, Farrugia G, Kashyap PC, Antonopoulos DA, Chang EB. Mutual reinforcement of pathophysiological host-microbe interactions in intestinal stasis models. Physiol Rep 2017 Mar; 5 (6)
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  5. Kashyap P. Beware! Are bacteria raising your oxidative stress? Sci Transl Med 2017 Feb 22; 9 (378)
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  6. Kashyap P. Tune into the rhythm of your bugs. Sci Transl Med 2017 Jan 11; 9 (372)
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  7. Wang F, Knutson K, Alcaino C, Linden DR, Gibbons SJ, Kashyap P, Grover M, Oeckler R, Gottlieb PA, Li HJ, Leiter AB, Farrugia G, Beyder A. Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces. J Physiol 2017 Jan 01; 595 (1):79-91 Epub 2016 Aug 13
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  8. Bhattarai Y, Muniz Pedrogo DA, Kashyap PC. Irritable bowel syndrome: a gut microbiota-related disorder? Am J Physiol Gastrointest Liver Physiol 2017 Jan 01; 312 (1):G52-G62 Epub 2016 Nov 23
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  9. Kashyap P. Bugs clogging your arteries? Take an anti-B2 shot. Sci Transl Med 2016 Nov 23; 8 (366):366ec187
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  10. Chen J, Toyomasu Y, Hayashi Y, Linden DR, Szurszewski JH, Nelson H, Farrugia G, Kashyap PC, Chia N, Ordog T. Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction. Genome Med 2016 Oct 03; 8 (1):103
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  11. Khanna S, Montassier E, Schmidt B, Patel R, Knights D, Pardi DS, Kashyap P. Gut microbiome predictors of treatment response and recurrence in primary Clostridium difficile infection. Aliment Pharmacol Ther 2016 Oct; 44 (7):715-727 Epub 2016 Aug 02
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  12. Reigstad CS, Linden DR, Szurszewski JH, Sonnenburg JL, Farrugia G, Kashyap PC. Correlated gene expression encoding serotonin (5-HT) receptor 4 and 5-HT transporter in proximal colonic segments of mice across different colonization states and sexes. Neurogastroenterol Motil 2016 Sep; 28 (9):1443-8 Epub 2016 Apr 12
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  13. Rajan E, Gostout CJ, Wong Kee Song LM, Szarka LA, Kashyap PC, Smyrk TC, Bingener J, Deters JL, Knipschield MA, Bernard CE, Farrugia G. Innovative gastric endoscopic muscle biopsy to identify all cell types, including myenteric neurons and interstitial cells of Cajal in patients with idiopathic gastroparesis: a feasibility study (with video). Gastrointest Endosc 2016 Sep; 84 (3):512-7 Epub 2016 Apr 27
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  14. Wadhwa A, Al Nahhas MF, Dierkhising RA, Patel R, Kashyap P, Pardi DS, Khanna S, Grover M. High risk of post-infectious irritable bowel syndrome in patients with Clostridium difficile infection. Aliment Pharmacol Ther 2016 Sep; 44 (6):576-82 Epub 2016 July 22
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  15. Nehra V, Allen JM, Mailing LJ, Kashyap PC, Woods JA. Gut Microbiota: Modulation of Host Physiology in Obesity. Physiology (Bethesda) 2016 Sep; 31 (5):327-35
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  16. Smits SA, Marcobal A, Higginbottom S, Sonnenburg JL, Kashyap PC. Individualized Responses of Gut Microbiota to Dietary Intervention Modeled in Humanized Mice. mSystems 2016 Sep-Oct; 1 (5) Epub 2016 Sept 06
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  17. Choi KM, Gibbons SJ, Sha L, Beyder A, Verhulst PJ, Cipriani G, Phillips JE, Bauer AJ, Ordog T, Camp JJ, Ge X, Bharucha AE, Linden DR, Szurszewski JH, Kashyap PC, Farrugia G. Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice. Cell Mol Gastroenterol Hepatol 2016 Jul; 2 (4):454-467 Epub 2016 Apr 23
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  18. Bhattarai Y, Kashyap PC. Agaro-oligosaccharides: a new frontier in the fight against colon cancer? Am J Physiol Gastrointest Liver Physiol 2016 Mar 15; 310 (6):G335-6 Epub 2016 Feb 11
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  19. Cipriani G, Gibbons SJ, Kashyap PC, Farrugia G. Intrinsic Gastrointestinal Macrophages: Their Phenotype and Role in Gastrointestinal Motility. Cell Mol Gastroenterol Hepatol 2016 Mar 01; 2 (2):120-130.e1
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  20. Bhattarai Y, Kashyap PC. Germ-Free Mice Model for Studying Host-Microbial Interactions. Methods Mol Biol 2016; 1438:123-35
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  21. Kashyap P. Microbes make the cancer Science Translational Medicine 2016; 8 (337):337ec71
  22. Kashyap P. I'll have a turkey and cheese sandwich Science Translational Medicine 2016; 8 (342):342ec91
  23. Kashyap P. Keep it moving Science Translational Medicine 2016; 8 (350):350ec125
  24. Kelly CR, Kahn S, Kashyap P, Laine L, Rubin D, Atreja A, Moore T, Wu G. Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook. Gastroenterology 2015 Jul; 149 (1):223-37 Epub 2015 May 15
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  25. Reigstad CS, Salmonson CE, Rainey JF 3rd, Szurszewski JH, Linden DR, Sonnenburg JL, Farrugia G, Kashyap PC. Gut microbes promote colonic serotonin production through an effect of short-chain fatty acids on enterochromaffin cells. FASEB J 2015 Apr; 29 (4):1395-403 Epub 2014 Dec 30
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  26. Yang AL, Kashyap PC. A clinical primer of the role of gut microbiome in health and disease. Trop Gastroenterol. 2015 Jan-Mar; 36(1):1-13.
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  27. Williams BB, Van Benschoten AH, Cimermancic P, Donia MS, Zimmermann M, Taketani M, Ishihara A, Kashyap PC, Fraser JS, Fischbach MA. Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine. Cell Host Microbe 2014 Oct 8; 16 (4):495-503 Epub 2014 Sept 25
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  28. Grover M, Kashyap PC. Germ-free mice as a model to study effect of gut microbiota on host physiology. Neurogastroenterol Motil 2014 Jun; 26 (6):745-8
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  29. Tong M, McHardy I, Ruegger P, Goudarzi M, Kashyap PC, Haritunians T, Li X, Graeber TG, Schwager E, Huttenhower C, Fornace AJ Jr, Sonnenburg JL, McGovern DP, Borneman J, Braun J. Reprogramming of gut microbiome energy metabolism by the FUT2 Crohn's disease risk polymorphism. ISME J.2014;
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  30. Kashyap PC, Marcobal A, Ursell LK, Smits SA, Sonnenburg ED, Costello EK, Higginbottom SK, Domino SE, Holmes SP, Relman DA, Knight R, Gordon JI, Sonnenburg JL. Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):17059-64. Epub 2013 Sep 23.
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  31. Ng KM, Ferreyra JA, Higginbottom SK, Lynch JB, Kashyap PC, Gopinath S, Naidu N, Choudhury B, Weimer BC, Monack DM, Sonnenburg JL. Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens. Nature. 2013 Oct 3; 502(7469):96-9. Epub 2013 Sep 01.
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  32. Marcobal A, Kashyap PC, Nelson TA, Aronov PA, Donia MS, Spormann A, Fischbach MA, Sonnenburg JL. A metabolomic view of how the human gut microbiota impacts the host metabolome using humanized and gnotobiotic mice. ISME J. 2013 Oct; 7(10):1933-43. Epub 2013 Jun 06.
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  33. Wieland Brown LC, Penaranda C, Kashyap PC, Williams BB, Clardy J, Kronenberg M, Sonnenburg JL, Comstock LE, Bluestone JA, Fischbach MA. Production of alpha-galactosylceramide by a prominent member of the human gut microbiota. PLoS Biol. 2013 Jul; 11(7):e1001610. Epub 2013 Jul 16.
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  34. Kashyap PC, Marcobal A, Ursell LK, Larauche M, Duboc H, Earle KA, Sonnenburg ED, Ferreyra JA, Higginbottom SK, Million M, Tache Y, Pasricha PJ, Knight R, Farrugia G, Sonnenburg JL. Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice. Gastroenterology. 2013 May; 144(5):967-77. Epub 2013 Feb 01.
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  35. Reigstad CS, Kashyap PC. Beyond phylotyping: understanding the impact of gut microbiota on host biology. Neurogastroenterol Motil 2013 May; 25 (5):358-72
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  36. Kashyap P, Gomez-Pinilla PJ, Pozo MJ, Cima RR, Dozois EJ, Larson DW, Ordog T, Gibbons SJ, Farrugia G. Immunoreactivity for Ano1 detects depletion of Kit-positive interstitial cells of Cajal in patients with slow transit constipation. Neurogastroenterol Motil 2011 Aug; 23 (8):760-5 Epub 2011 May 17
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  37. Kashyap P, Medeiros F, Levy M, Larson M. Unusual submucosal tumor in the stomach. Diagnosis: Endometriosis. Gastroenterology 2011 Jun; 140 (7):e7-8 Epub 2011 Apr 28
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  38. Sweetser S, Kashyap P, Baron TH. Percutaneous endoscopic gastrostomy tract salvage using natural orifice transluminal endoscopic surgery technique (with video). Gastrointest Endosc. 2011 Apr; 73(4):839-40. Epub 2010 Nov 09.
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  39. Kashyap P, Sweetser S, Farrugia G. Esophageal papillomas and skin abnormalities. Focal dermal hypoplasia (Goltz syndrome) manifesting with esophageal papillomatosis. Gastroenterology. 2011 Mar; 140(3):784, 1111. Epub 2011 Jan 25.
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  40. Kashyap P, Farrugia G. Diabetic gastroparesis: what we have learned and had to unlearn in the past 5 years. Gut 2010 Dec; 59 (12):1716-26 Epub 2010 Sept 25
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  41. Medeiros F, Araujo AR, Erickson-Johnson MR, Kashyap PC, Dal Cin P, Nucci M, Wang X, Bell DA, Oliveira AM. HMGA1 and HMGA2 rearrangements in mass-forming endometriosis. Genes Chromosomes Cancer 2010 Jul; 49 (7):630-4
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  42. Choi KM, Kashyap PC, Dutta N, Stoltz GJ, Ordog T, Shea Donohue T, Bauer AJ, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G. CD206-positive M2 macrophages that express heme oxygenase-1 protect against diabetic gastroparesis in mice. Gastroenterology 2010 Jun; 138 (7):2399-409, 2409.e1 Epub 2010 Feb 20
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  43. Kashyap PC, Choi KM, Dutta N, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G. Carbon monoxide reverses diabetic gastroparesis in NOD mice. Am J Physiol Gastrointest Liver Physiol 2010 Jun; 298 (6):G1013-9 Epub 2010 Apr 08
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  44. Kashyap PC, Kelly B, Ghera P. "Nephrogenic systemic fibrosis following acute kidney injury and exposure to gadolinium". Indian J Med Sci.2010 Jan;64:(1):33-6.
  45. Kashyap P, Micci MA, Pasricha S, Pasricha PJ. The D2/D3 agonist PD128907 (R-(+)-trans-3,4a,10b-tetrahydro-4-propyl-2H,5H-[1]benzopyrano[4,3-b]-1,4-oxazin- 9-ol) inhibits stimulated pyloric relaxation and spontaneous gastric emptying. Dig Dis Sci. 2009 Jan; 54(1):57-62. Epub 2008 Jul 4
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  46. Kashyap P, Farrugia G. Enteric autoantibodies and gut motility disorders. Gastroenterol Clin North Am 2008 Jun; 37 (2):397-410, vi-vii
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  47. Singh N, Deb R, Kashyap PC, Bhatia V, Ahuja V, Sharma MP. Body mass index and per capita income influence duodenal ulcer healing and H. pylori eradication whilst dietary factors play no part. Trop Gastroenterol. 2008 Jan-Mar; 29(1):26-31.
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  48. Madan K, Ahuja V, Kashyap PC, Sharma MP. Comparison of efficacy of pantoprazole alone versus pantoprazole plus mosapride in therapy of gastroesophageal reflux disease: a randomized trial. Dis Esophagus. 2004; 17(4):274-8.
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  49. Kashyap PC, Ahuja V. Strategies to treat Helicobacter pylori in peptic ulcer disease. Gastroenterology Today. 2002; 6:126-129.