Publications

  1. Karnatovskaia LV, Wartenberg KE, Freeman WD. Therapeutic hypothermia for neuroprotection: history, mechanisms, risks, and clinical applications. Neurohospitalist. 2014 Jul; 4(3):153-63.
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  2. Festic E, Siegel J, Stritt M, Freeman WD. The utility of serum procalcitonin in distinguishing systemic inflammatory response syndrome from infection after aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2014 Jun; 20(3):375-81.
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  3. Smith CC, Tatum WO, Gupta V, Pooley RA, Freeman WD. SPECT-Negative SIRPIDs: Less Aggressive Neurointensive Care? J Clin Neurophysiol. 2014 Jun; 31(3):e6-e10.
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  4. Karnatovskaia LV, Festic E, Freeman WD, Lee AS. Effect of therapeutic hypothermia on gas exchange and respiratory mechanics: a retrospective cohort study. Ther Hypothermia Temp Manag. 2014 Jun; 4(2):88-95. Epub 2014 May 19.
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  5. Karnatovskaia LV, Lee AS, Festic E, Kramer CL, Freeman WD. Effect of Prolonged Therapeutic Hypothermia on Intracranial Pressure, Organ Function, and Hospital Outcomes Among Patients with Aneurysmal Subarachnoid Hemorrhage. Neurocrit Care. 2014 May 28.
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  6. Freeman WD. Thresholds for cerebral perfusion pressure. Pediatr Crit Care Med. 2014 May; 15(4):388.
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  7. Ranasinghe T, Freeman WD. Vein of trolard sign on noncontrast computed tomography in Behcet's disease. Acta Med Acad. 2014 May; 43(1):97-8.
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  8. Hanel RA, Taussky P, Dixon T, Miller DA, Sapin M, Nordeen JD, Tawk RG, Navarro R, Johns G, Freeman WD. Safety and efficacy of ticagrelor for neuroendovascular procedures. A single center initial experience. J Neurointerv Surg. 2014 May; 6(4):320-2. Epub 2013 Jun 14.
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  9. Lewandowski-Belfer JJ, Patel AV, Darracott RM, Jackson DA, Nordeen JD, Freeman WD. Safety and efficacy of repeated doses of 14.6 or 23.4 % hypertonic saline for refractory intracranial hypertension. Neurocrit Care. 2014; 20(3):436-42.
  10. Aguilar MI, Kuo RS, Freeman WD. New anticoagulants (dabigatran, apixaban, rivaroxaban) for stroke prevention in atrial fibrillation. Neurol Clin. 2013 Aug; 31(3):659-75.
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  11. Taussky P, Tawk RG, Miller DA, Freeman WD, Hanel RA. New therapies for unruptured intracranial aneurysms. Neurol Clin. 2013 Aug; 31(3):737-47. Epub 2013 May 17.
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  12. Jackson DA, Patel AV, Darracott RM, Hanel RA, Freeman WD, Hanley DF. Safety of intraventricular hemorrhage (IVH) thrombolysis based on CT localization of external ventricular drain (EVD) fenestrations and analysis of EVD tract hemorrhage. Neurocrit Care. 2013 Aug; 19(1):103-10.
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  13. Freeman WD, Vatz KA, Griggs RC, Pedley T. The Workforce Task Force report: clinical implications for neurology. Neurology. 2013 Jul 30; 81(5):479-86. Epub 2013 Jun 19.
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  14. Silva MD, Brazis P, Miller D, Wharen R, Smith CC, Freeman WD. True- true- unrelated? A deplayed onset, complete third-nerve palsy after traumatic subarachnoid hemorrhage. J Vasc Interv Neurol. 2013 Jun; 6(1):22-5.
  15. Nordeen JD, Patel AV, Darracott RM, Johns GS, Taussky P, Tawk RG, Miller DA, Freeman WD, Hanel RA. Clopidogrel Resistance by P2Y12 Platelet Function Testing in Patients Undergoing Neuroendovascular Procedures: Incidence of Ischemic and Hemorrhagic Complications. J Vasc Interv Neurol. 2013 Jun; 6(1):26-34.
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  16. Festic E, Rabinstein AA, Freeman WD, Mauricio EA, Robinson MT, Mandrekar J, Zubair AC, Lee AS, Gajic O. Blood transfusion is an important predictor of hospital mortality among patients with aneurysmal subarachnoid hemorrhage. Neurocrit Care. 2013 Apr; 18(2):209-15.
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  17. Cantador AA, Meschia JF, Freeman WD, Tatum WO. Nonconvulsive Status with Metronidazole. The Neurohospitalist. 2013 Jan 24. [Epub ahead of print]
  18. Lewandowski-Belfer JJ, Patel AV, Darracott RM, Jackson DA, Nordeen JD, Freeman WD. Safety and efficacy of repeated doses of 14.6 or 23.4% hypertonic saline for refractory intracranial hypertension. Neurocrit Care. 2013.
  19. Freeman WD, Barrett KM, Vatz KA, Demaerschalk BM. Future neurohospitalist: teleneurohospitalist. Neurohospitalist. 2012 Oct; 2(4):132-43.
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  20. Douglas VC, Scott BJ, Berg G, Freeman WD, Josephson SA. Effect of a neurohospitalist service on outcomes at an academic medical center. Neurology. 2012 Sep 4; 79(10):988-94. Epub 2012 Aug 22.
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  21. Luk ME, Tatum WO, Patel AV, Nau KM, Freeman WD. The safety of lacosamide for treatment of seizures and seizure prophylaxis in adult hospitalized patients. Neurohospitalist. 2012 Jul; 2(3):77-81.
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  22. Lu N, Jackson D, Luke S, Festic E, Hanel RA, Freeman WD. Intraventricular nicardipine for aneurysmal subarachnoid hemorrhage related vasospasm: assessment of 90 days outcome. Neurocrit Care. 2012 Jun; 16(3):368-75.
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  23. Rabinstein AA, Yee AH, Mandrekar J, Fugate JE, de Groot YJ, Kompanje EJ, Shutter LA, Freeman WD, Rubin MA, Wijdicks EF. Prediction of potential for organ donation after cardiac death in patients in neurocritical state: a prospective observational study. Lancet Neurol. 2012 May; 11(5):414-9. Epub 2012 Apr 10.
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  24. Kramer C, Freeman WD, Larson JS, Hoffman-Snyder C, Wellik KE, Demaerschalk BM, Wingerchuk DM. Therapeutic hypothermia for severe traumatic brain injury: a critically appraised topic. Neurologist. 2012 May; 18(3):173-7.
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  25. Carrigan WV 3rd, Barrett K, Freeman WD, Avalon N. Multimodal CT to Differentiate Acute Ischemic Stroke From Stroke Mimics. Neurohospitalist. 2012 Apr; 2(2):60-1.
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  26. Freeman WD, Aguilar MI. Intracranial hemorrhage: diagnosis and management. Neurol Clin. 2012 Feb; 30(1):211-40, ix.
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  27. Taussky P, O'Neal B, Daugherty WP, Luke S, Thorpe D, Pooley RA, Evans C, Hanel RA, Freeman WD. Validation of frontal near-infrared spectroscopy as noninvasive bedside monitoring for regional cerebral blood flow in brain-injured patients. Neurosurg Focus. 2012 Feb; 32(2):E2.
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  28. Likosky DJ, Josephson SA, Coleman M, Freeman WD, Biller J. Survey of current neurohospitalist practice. Neurology: Clinical Practice. 2012; 2(4):319-27.
  29. Rahmlow MR, Boylan K, Freeman WD. Diaphragmatic pacing to facilitate ventilator weaning in neuromyelitis optica-associated respiratory failure. Multiple Sclerosis and Related Disorders. 2012; 1(3):145-7.
  30. Freeman WD, Dorsher PT, Safford RE, Van Gerpen J, Edwards WD. Combined pergolide-associated valvular heart disease and achilles tendon contractures. Acta Med Acad. 2012; 41(2):228-30.
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  31. Cyrous A, O'Neal B, Freeman WD. New approaches to bedside monitoring in stroke. Expert rev. neurotherapeutics. 2012; 12(8):915-28.
  32. Jerath NU, Reddy C, Freeman WD, Jerath AU, Brown RD. Gender differences in presenting signs and symptoms of acute ischemic stroke: a population-based study. Gend Med. 2011 Oct; 8(5):312-9. Epub 2011 Sep 16.
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  33. Chiota NA, Freeman WD, Barrett KM. Hypoxic-ischemic brain injury and prognosis after cardiac arrest. Continuum. 2011 Oct; 17(5):1094-118.
  34. Walsh RD, Barrett KM, Aguilar MI, Lanzino G, Hanel RA, Miller DA, Chong BW, Freeman WD. Intracranial hemorrhage following neuroendovascular procedures with abciximab is associated with high mortality: a multicenter series. Neurocrit Care. 2011 Aug; 15(1):85-95.
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  35. Freeman WD, Aguilar MI. Prevention of cardioembolic stroke. Neurotherapeutics. 2011 Jul; 8(3):488-502.
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  36. Rancier R, Woessner H, Freeman WD. The diffuse hyperdense intracranial circulation sign. Neurohospitalist. 2011 Jul; 1(3):137.
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  37. Tatum WO, Dworetzky BA, Freeman WD, Schomer DL. Artifact: recording EEG in special care units. J Clin Neurophysiol. 2011 Jun; 28(3):264-77.
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  38. Bacani CJ, Freeman WD, Di Trapani RA, Canabal JC, Arasi L, Shine T, Willingham DL. Emergent, controlled lumbar drainage for intracranial pressure monitoring during orthotopic liver transplantation. Neurocrit Care. 2011 Jun; 14(3):447-52.
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  39. Barrett KM, Brott TG, Brown RD Jr, Carter RE, Geske JR, Graff-Radford NR, McNeil RB, Meschia JF, Mayo Acute Stroke Trial for Enhancing Recovery (MASTER) Study Group. Enhancing recovery after acute ischemic stroke with donepezil as an adjuvant therapy to standard medical care: results of a phase IIA clinical trial. J Stroke Cerebrovasc Dis. 2011 May-Jun; 20(3):177-82. Epub 2011 Feb 03.
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  40. Freeman WD, Dawson SB, Raper C, Thiemann K, Josephson SA, Barrett KM. Neurohospitalists reduce length of stay for patients with ischemic stroke. Neurohospitalist. 2011 Apr; 1(2):67-70.
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  41. Freeman WD, Nolte CM, Matthews BR, Coleman M, Corboy JR. Results of the American Academy of Neurology resident survey. Neurology. 2011 Mar 29; 76(13):e61-7.
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  42. Freeman WD, Josephson SA. The birth of neurohospitalists. Neurohospitalist. 2011 Jan; 1(1):5-7.
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  43. Chiota NA, Freeman WD, Barrett K. Earlier Hypothermia Attainment is Associated with Improved Outcomes after Cardiac Arrest. J Vasc Interv Neurol. 2011 Jan; 4(1):14-7.
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  44. Mauricio EA, Freeman WD. Status epilepticus in the elderly: differential diagnosis and treatment. Neuropsychiatr Dis Treat. 2011; 7:161-6. Epub 2011 Mar 29.
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  45. Smith EH, Gavrilov DK, Oglesbee D, Freeman WD, Vavra MW, Matern D, Tortorelli S. An adult onset case of alpha-methyl-acyl-CoA racemase deficiency. J Inherit Metab Dis. 2010 Dec; 33 Suppl 3:S349-53. Epub 2010 Sep 04.
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  46. Aguilar MI, Freeman WD. Spontaneous intracerebral hemorrhage. Semin Neurol. 2010 Nov; 30(5):555-64. Epub 2011 Jan 04.
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  47. Freeman WD, Dawson SB, Flemming KD. The ABC's of stroke complications. Semin Neurol. 2010 Nov; 30(5):501-10. Epub 2011 Jan 04.
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  48. Robinson MT, Rabinstein AA, Meschia JF, Freeman WD. Safety of recombinant activated factor VII in patients with warfarin-associated hemorrhages of the central nervous system. Stroke. 2010 Jul; 41(7):1459-63. Epub 2010 Jun 03.
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  49. Freeman WD, Vatz KA. The future of neurology. Neurol Clin. 2010 May; 28(2):537-61.
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  50. Aguilar MI, Freeman WD. Treatment of coagulopathy in intracranial hemorrhage. Curr Treat Options Neurol. 2010 Mar; 12(2):113-28.
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  51. Albright KC, Freeman WD, Kruse BT. Cerebral venous thrombosis. J Emerg Med. 2010 Feb; 38(2):238-9. Epub 2008 Jul 09.
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  52. Barrett KM, Freeman WD. Emerging subspecialties in neurology: neurohospitalist. Neurology. 2010 Jan 12; 74(2):e9-10.
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  53. Freeman WD, Aguilar M. Anticoagulation therapy for cardioembolic stroke prevention in the elderly: Defining benefits and risks. Aging Health. 2010; 6(4):439-50.
  54. Freeman WD, Aguilar MI. Anticoagulation Therapy for Stroke: Risks and Benefits in the Aged. Aging Health. 2010.
  55. Freeman WD, Palmer S, Freeman ML, Barrett KM. Reversible delayed hypoxic leukoencephalopathy associated with methadone overdose. Acta Medica Academica. 2010; 39(1).
  56. Likosky D, Shulman S, Restrepo L, Freeman WD. Survey of neurohospitalists: Subspecialty definition and practice characteristics. Frontiers in Neurology. 2010; Jun:9.
  57. Mateen FJ, Nasser M, Spencer BR, Freeman WD, Shuaib A, Demaerschalk BM, Wijdicks EF. Outcomes of intravenous tissue plasminogen activator for acute ischemic stroke in patients aged 90 years or older. Mayo Clin Proc. 2009 Apr; 84(4):334-8.
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  58. Spector AR, Freeman WD, Cheshire WP. The stroke that struck back: an unusual alien hand presentation. J Stroke Cerebrovasc Dis. 2009 Jan; 18(1):72-3.
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  59. Ng HK, Hanel R, Freeman W. Prolonged Mild-to-Moderate Hypothermia for Refractory Intracranial Hypertension. J Vasc Interv Neurol. 2009 Jan; 2(1):142-6.
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  60. Rowley M, Riutort K, Shapiro D, Casler J, Festic E, Freeman WD. Methylene blue-associated serotonin syndrome: a 'green' encephalopathy after parathyroidectomy. Neurocrit Care. 2009; 11(1):88-93. Epub 2009 Mar 05.
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  61. Nau KM, Divertie GD, Valentino AK, Freeman WD. Safety and efficacy of levetiracetam for critically ill patients with seizures. Neurocrit Care. 2009; 11(1):34-7. Epub 2009 Jan 29.
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  62. Freeman WD, Aguilar MI. Stroke prevention in atrial fibrillation and other major cardiac sources of embolism. Neurol Clin. 2008 Nov; 26(4):1129-60, x-xi.
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  63. Rahmlow M, Shuster EA, Dominik J, Deen HG Jr, Dickson DW, Aksamit AJ Jr, Robles HA, Freeman WD. Leflunomide-associated progressive multifocal leukoencephalopathy. Arch Neurol. 2008 Nov; 65(11):1538-9.
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  64. Valentino AK, Nau KM, Miller DA, Hanel RA, Freeman W. Repeated dosing of 23.4% hypertonic saline for refractory intracranial hypertension. A case report. J Vasc Interv Neurol. 2008 Oct; 1(4):113-7.
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  65. Barrett KM, Freeman WD. 71-year-old woman with loss of right-sided vision and cognitive deficits. Mayo Clin Proc. 2008 Jun; 83(6):708-11.
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  66. Konieczny PL, Eidelman BH, Freeman WD. Teaching video neuroimage: Foix-Chavany-Marie syndrome. Neurology. 2008 May 20; 70(21):e88.
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  67. Freeman WD, Gronseth G, Eidelman BH. Invited article: is it time for neurohospitalists? Neurology. 2008 Apr 8; 70(15):1282-8. Epub 2008 Mar 12.
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  68. Freeman WD, Aguilar MI. Management of warfarin-related intracerebral hemorrhage. Expert Rev Neurother. 2008 Feb; 8(2):271-90.
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  69. Freeman WD, Barrett KM, Bestic JM, Meschia JF, Broderick DF, Brott TG. Computer-assisted volumetric analysis compared with ABC/2 method for assessing warfarin-related intracranial hemorrhage volumes. Neurocrit Care. 2008; 9(3):307-12.
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  70. Manno EM, Rabinstein AA, Wijdicks EF, Brown AW, Freeman WD, Lee VH, Weigand SD, Keegan MT, Brown DR, Whalen FX, Roy TK, Hubmayr RD. A prospective trial of elective extubation in brain injured patients meeting extubation criteria for ventilatory support: a feasibility study. Crit Care. 2008; 12(6):R138. Epub 2008 Nov 10.
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  71. Aguilar MI, Freeman WD. Warfarin-related intracerebral hemorrhage: How to proceed. Aging Health. 2008; 4(3):299-310.
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  72. Barrett KM, Freeman WD, Weindling SM, Brott TG, Broderick DF, Heckman MG, Crook JE, Divertie GD, Meschia JF. Brain injury after cardiopulmonary arrest and its assessment with diffusion-weighted magnetic resonance imaging. Mayo Clin Proc. 2007 Jul; 82(7):828-35.
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  73. Gill DJ, Freeman WD, Thoresen P, Corboy JR. Residency training the neurology resident case log: a national survey of neurology residents. Neurology. 2007 May 22; 68(21):E32-3.
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  74. Aguilar MI, Hart RG, Kase CS, Freeman WD, Hoeben BJ, Garcia RC, Ansell JE, Mayer SA, Norrving B, Rosand J, Steiner T, Wijdicks EF, Yamaguchi T, Yasaka M. Treatment of warfarin-associated intracerebral hemorrhage: literature review and expert opinion. Mayo Clin Proc. 2007 Jan; 82(1):82-92.
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  75. Linos K, Foot C, Ziegenfuss M, Freeman WD, Tan KM. Critical illness weakness: Common questions. Curr Anaesth Crit Care. 2007; 18(5-6):252-60.
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  76. Linos K, Fraser J, Freeman WD, Foot C. Care of the brain-dead organ donor. Curr Anaesth Crit Care. 2007; 18(5-6):284-94.
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  77. Heaney M, Foot C, Freeman WD, Fraser J. Ethical issues in withholding and withdrawing life-prolonging medical treatment in the ICU. Curr Anaesth Crit Care. 2007; 18(5-6):277-83.
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  78. Freeman WD, Tan KM, Glass GA, Linos K, Foot C, Ziegenfuss M. ICU management of patients with Parkinson's disease or Parkinsonism. Curr Anaesth Crit Care. 2007; 18(5-6):227-36.
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  79. Freeman WD, Sen S, Roy TK, Wijdicks EF. Cluster breathing associated with bihemispheric infarction and sparing of the brainstem. Arch Neurol. 2006 Oct; 63(10):1487-90.
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  80. Freeman WD, Brott TG. Modern treatment options for intracerebral hemorrhage. Curr Treat Options Neurol. 2006 Mar; 8(2):145-57.
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  81. Baba Y, Hentschel K, Freeman WD, Broderick DF, Wszolek ZK. Large paraspinal and iliopsoas muscle hematomas. Archives of Neurology. 2005 Aug; 62(8):1306.
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  82. Freeman WD, Chabolla DR. 36-Year-old woman with loss of consciousness, fever, and tachycardia. Mayo Clin Proc. 2005 May; 80(5):667-70.
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  83. Freeman WD, Cheshire WP. A callused clue fingers the diagnosis. Arch Neurol. 2005 Mar; 62(3):491.
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  84. Freeman WD, Maramattom B, Czervionke L, Manno EM. Pituitary apoplexy. Neurocrit Care. 2005; 3(2):174-6.
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  85. Freeman WD, Brott TG, Barrett KM, Castillo PR, Deen HG Jr, Czervionke LF, Meschia JF. Recombinant factor VIIa for rapid reversal of warfarin anticoagulation in acute intracranial hemorrhage. Mayo Clin Proc. 2004 Dec; 79(12):1495-500.
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