Publications

  1. Simha V, Qin S, Shah P, Smith BH, Kremers WK, Kushwaha S, Wang L, Pereira NL. Sirolimus Therapy Is Associated with Elevation in Circulating PCSK9 Levels in Cardiac Transplant Patients. J Cardiovasc Transl Res 2017 Feb; 10 (1):9-15 Epub 2016 Dec 27
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  2. Moriarty PM, Parhofer KG, Babirak SP, Cornier MA, Duell PB, Hohenstein B, Leebmann J, Ramlow W, Schettler V, Simha V, Steinhagen-Thiessen E, Thompson PD, Vogt A, von Stritzky B, Du Y, Manvelian G. Alirocumab in patients with heterozygous familial hypercholesterolaemia undergoing lipoprotein apheresis: the ODYSSEY ESCAPE trial. Eur Heart J 2016 Dec 21; 37 (48):3588-3595 Epub 2016 Aug 29
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  3. Simha V, Kudva YC. HDL Cholesterol Story Is Dead: Long Live HDL! Diabetes 2016 Oct; 65 (10):2826-8
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  4. Moriarty PM, Parhofer KG, Babirak SP, deGoma E, Duell PB, Hohenstein B, Ramlow W, Simha V, Steinhagen-Thiessen E, Thompson PD, Vogt A, von Stritzky B, Du Y, Manvelian G. Alirocumab in patients with heterozygous familial hypercholesterolemia undergoing lipoprotein apheresis: Rationale and design of the ODYSSEY ESCAPE trial. J Clin Lipidol 2016 May-Jun; 10 (3):627-34 Epub 2016 Feb 18
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  5. Musso C, Major ML, Andres E, Simha V. Metreleptin treatment in three patients with generalized lipodystrophy Clinical Medicine Insights-Case Reports 2016; 9:123-7
  6. Simha V. Drug-induced dyslipidemia Contemporary Endocrinology 2015; 1:267-86
  7. Lopez-Jimenez F, Simha V, Thomas RJ, Allison TG, Basu A, Fernandes R, Hurst RT, Kopecky SL, Kullo IJ, Mulvagh SL, Thompson WG, Trejo-Gutierrez JF, Wright RS. A summary and critical assessment of the 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk in adults: filling the gaps. Mayo Clin Proc. 2014 Sep; 89(9):1257-78. Epub 2014 Aug 12.
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  8. Simha V. Metreleptin for metabolic disorders associated with generalized or partial lipodystrophy. Expert Rev. Endocrinol. Metab. 2014; 9(3):205-12.
  9. Nelson MD, Victor RG, Szczepaniak EW, Simha V, Garg A, Szczepaniak LS. Cardiac steatosis and left ventricular hypertrophy in patients with generalized lipodystrophy as determined by magnetic resonance spectroscopy and imaging. Am J Cardiol. 2013 Oct 1; 112(7):1019-24. Epub 2013 Jun 22.
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  10. Ahmad Z, Subramanyam L, Szczepaniak L, Simha V, Adams-Huet B, Garg A. Cholic acid for hepatic steatosis in patients with lipodystrophy: a randomized, controlled trial. Eur J Endocrinol. 2013 May; 168(5):771-8. Epub 2013 Apr 15.
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  11. Simha V, Mahmood M, Ansari M, Spellman CW, Shah P. Effect of vitamin D replacement on insulin sensitivity in subjects with vitamin D deficiency. J Investig Med 2012 Dec; 60 (8):1214-8
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  12. Simha V, Subramanyam L, Szczepaniak L, Quittner C, Adams-Huet B, Snell P, Garg A. Comparison of efficacy and safety of leptin replacement therapy in moderately and severely hypoleptinemic patients with familial partial lipodystrophy of the Dunnigan variety. J Clin Endocrinol Metab. 2012 Mar; 97(3):785-92. Epub 2011 Dec 14.
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  13. Shrikanth V, Vanderheiden A, Simha V. Spontaneous intracerebral hemorrhage associated with ingestion of isometheptine containing anti-migraine medication. Clin Neurol Neurosurg. 2011 Feb; 113(2):167-9. Epub 2010 Nov 13.
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  14. Shastry S, Simha V, Godbole K, Sbraccia P, Melancon S, Yajnik CS, Novelli G, Kroiss M, Garg A. A novel syndrome of mandibular hypoplasia, deafness, and progeroid features associated with lipodystrophy, undescended testes, and male hypogonadism. J Clin Endocrinol Metab. 2010 Oct; 95(10):E192-7. Epub 2010 Jul 14.
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  15. Subramanyam L, Simha V, Garg A. Overlapping syndrome with familial partial lipodystrophy, Dunnigan variety and cardiomyopathy due to amino-terminal heterozygous missense lamin A/C mutations. Clin Genet. 2010 Jul; 78(1):66-73. Epub 2009 Dec 22.
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  16. Ahmed K, Rao S, Simha V. Antineutrophil cytoplasmic antibody-positive vasculitis in a patient with graves disease: cross-reaction between propylthiouracil and methimazole. Endocr Pract. 2010 May-Jun; 16(3):449-51.
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  17. Garg A, Subramanyam L, Agarwal AK, Simha V, Levine B, D'Apice MR, Novelli G, Crow Y. Atypical progeroid syndrome due to heterozygous missense LMNA mutations. J Clin Endocrinol Metab. 2009 Dec; 94(12):4971-83. Epub 2009 Oct 29.
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  18. Simha V, Garg A. Inherited lipodystrophies and hypertriglyceridemia. Curr Opin Lipidol. 2009 Aug; 20(4):300-8.
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  19. Keller J, Subramanyam L, Simha V, Gustofson R, Minjarez D, Garg A. Lipodystrophy: an unusual diagnosis in a case of oligomenorrhea and hirsutism. Obstet Gynecol. 2009 Aug; 114(2 Pt 2):427-31.
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  20. Simha V, Agarwal AK, Aronin PA, Iannaccone ST, Garg A. Novel subtype of congenital generalized lipodystrophy associated with muscular weakness and cervical spine instability. Am J Med Genet A. 2008 Sep 15; 146A(18):2318-26.
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  21. Simha V. Dietary carbohydrates and risk of type 2 diabetes: are rice eaters doomed? Natl Med J India. 2008 Mar-Apr; 21(2):80-1.
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  22. O'Neill B, Simha V, Kotha V, Garg A. Body fat distribution and metabolic variables in patients with neonatal progeroid syndrome. Am J Med Genet A. 2007 Jul 1; 143A(13):1421-30.
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  23. Garg A, Simha V. Update on dyslipidemia. J Clin Endocrinol Metab. 2007 May; 92(5):1581-9.
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  24. Shah M, Simha V, Garg A. Review: long-term impact of bariatric surgery on body weight, comorbidities, and nutritional status. J Clin Endocrinol Metab. 2006 Nov; 91(11):4223-31. Epub 2006 Sep 5
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  25. Simha V, Garg A. Lipodystrophy: lessons in lipid and energy metabolism. Curr Opin Lipidol. 2006 Apr; 17(2):162-9.
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  26. Simha V, Garg A. Phenotypic heterogeneity in body fat distribution in patients with congenital generalized lipodystrophy caused by mutations in the AGPAT2 or seipin genes. J Clin Endocrinol Metab. 2003 Nov; 88(11):5433-7.
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  27. Agarwal AK, Simha V, Oral EA, Moran SA, Gorden P, O'Rahilly S, Zaidi Z, Gurakan F, Arslanian SA, Klar A, Ricker A, White NH, Bindl L, Herbst K, Kennel K, Patel SB, Al-Gazali L, Garg A. Phenotypic and genetic heterogeneity in congenital generalized lipodystrophy. J Clin Endocrinol Metab. 2003 Oct; 88(10):4840-7.
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  28. Simha V, Agarwal AK, Oral EA, Fryns JP, Garg A. Genetic and phenotypic heterogeneity in patients with mandibuloacral dysplasia-associated lipodystrophy. J Clin Endocrinol Metab. 2003 Jun; 88(6):2821-4.
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  29. Simha V, Szczepaniak LS, Wagner AJ, DePaoli AM, Garg A. Effect of leptin replacement on intrahepatic and intramyocellular lipid content in patients with generalized lipodystrophy. Diabetes Care. 2003 Jan; 26(1):30-5.
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  30. Simha V, Zerwekh JE, Sakhaee K, Garg A. Effect of subcutaneous leptin replacement therapy on bone metabolism in patients with generalized lipodystrophy. J Clin Endocrinol Metab. 2002 Nov; 87(11):4942-5.
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  31. Oral EA, Simha V, Ruiz E, Andewelt A, Premkumar A, Snell P, Wagner AJ, DePaoli AM, Reitman ML, Taylor SI, Gorden P, Garg A. Leptin-replacement therapy for lipodystrophy. N Engl J Med. 2002 Feb 21; 346(8):570-8.
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  32. Simha V, Garg A. Body fat distribution and metabolic derangements in patients with familial partial lipodystrophy associated with mandibuloacral dysplasia. J Clin Endocrinol Metab. 2002 Feb; 87(2):776-85.
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