Publications

  1. Banck MS, Meier-Abt PJ, Gerloff T, Hemmi S, Beutler AS. A slowly growing human cholangiocarcinoma is highly sensitive to HSVtk gene therapy. GI Cancer. 2001; 3:343-53.
  2. Storek B, Reinhardt M, Wang C, Janssen WG, Harder NM, Banck MS, Morrison JH, Beutler AS. Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain. Proc Natl Acad Sci U S A. 2008 Jan 22; 105(3):1055-60.
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  3. Banck MS, Li S, Nishio H, Wang C, Beutler AS, Walsh MJ. The ZNF217 oncogene is a candidate organizer of repressive histone modifiers. Epigenetics. 2009 Feb; 4(2):100-6. Epub 2009 Feb 23.
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  4. Beutler AS, Banck MS, Bach FW, Gage FH, Porreca F, Bilsky EJ, Yaksh TL. Retrovirus-mediated expression of an artificial beta-endorphin precursor in primary fibroblasts. J Neurochem. 1995 Feb; 64(2):475-81.
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  5. Beutler AS, Banck MS, Wedekind D, Hedrich HJ. Tumor gene therapy made easy: allogeneic major histocompatibility complex in the C6 rat glioma model. Hum Gene Ther. 1999 Jan 1; 10(1):95-101.
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  6. Beutler AS, Banck MS, Walsh CE, Milligan ED. Intrathecal gene transfer by adeno-associated virus for pain. Curr Opin Mol Ther. 2005 Oct; 7(5):431-9.
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  7. Storek B, Harder NM, Banck MS, Wang C, McCarty DM, Janssen WG, Morrison JH, Walsh CE, Beutler AS. Intrathecal long-term gene expression by self-complementary adeno-associated virus type 1 suitable for chronic pain studies in rats. Mol Pain. 2006; 2:4. Epub 2006 Jan 30.
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  8. Banck MS, Beaven SW, Narla G, Walsh MJ, Friedman SL, Beutler AS. KLF6 degradation after apoptotic DNA damage. FEBS Lett. 2006 Dec 22; 580(30):6981-6. Epub 2006 Nov 13.
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  9. Beutler AS, Reinhardt M. AAV for pain: steps towards clinical translation. Gene Ther. 2009 Apr; 16(4):461-9. Epub 2009 Mar 05.
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  10. Beutler AS, Li S, Nicol R, Walsh MJ. Carbamazepine is an inhibitor of histone deacetylases. Life Sci. 2005 May 13; 76(26):3107-15.
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  11. Schwartz JD, Beutler AS. Therapy for unresectable hepatocellular carcinoma: review of the randomized clinical trials-II: systemic and local non-embolization-based therapies in unresectable and advanced hepatocellular carcinoma. Anticancer Drugs. 2004 Jun; 15(5):439-52.
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  12. Paulus W, Baur I, Beutler AS, Reeves SA. Diffuse brain invasion of glioma cells requires beta 1 integrins. Lab Invest. 1996 Dec; 75(6):819-26.
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  13. Lang EW, Chesnut RM, Beutler AS, Kennelly NA, Renaudin JW. The utility of motor-evoked potential monitoring during intramedullary surgery. Anesth Analg. 1996 Dec; 83(6):1337-41.
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  14. Lang EW, Beutler AS, Chesnut RM, Patel PM, Kennelly NA, Kalkman CJ, Drummond JC, Garfin SR. Myogenic motor-evoked potential monitoring using partial neuromuscular blockade in surgery of the spine. Spine. 1996 Jul 15; 21(14):1676-86.
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  15. Beutler AS, Hsiang JK, Moorhouse DF, Hansen LA, Alksne JF. Pilocytic astrocytoma presenting as an extra-axial tumor in the cerebellopontine angle: case report. Neurosurgery. 1995 Jul; 37(1):125-8.
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  16. Ray J, Hogg J, Beutler AS, Takayama H, Baird A, Gage FH. Expression of biologically active basic fibroblast growth factor by genetically modified rat primary skin fibroblasts. J Neurochem. 1995 Feb; 64(2):503-13.
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  17. Hammer P, Banck MS, Amberg R, Wang C, Petznick G, Luo S, Khrebtukova I, Schroth GP, Beyerlein P, Beutler AS. mRNA-seq with agnostic splice site discovery for nervous system transcriptomics tested in chronic pain. Genome Res. 2010 Jun; 20(6):847-60. Epub 2010 May 07.
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  18. Hartung T, Zhang L, Kanwar R, Khrebtukova I, Reinhardt M, Wang C, Therneau TM, Banck MS, Schroth GP, Beutler AS. Diametrically opposite methylome-transcriptome relationships in high- and low-CpG promoter genes in postmitotic neural rat tissue. Epigenetics. 2012 May; 7(5):421-8. Epub 2012 May 01.
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  19. Sun Z, Baheti S, Middha S, Kanwar R, Zhang Y, Li X, Beutler AS, Klee E, Asmann YW, Thompson EA, Kocher JP. SAAP-RRBS: streamlined analysis and annotation pipeline for reduced representation bisulfite sequencing. Bioinformatics. 2012 Aug 15; 28(16):2180-1. Epub 2012 Jun 10.
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  20. Schulze SK, Kanwar R, Golzenleuchter M, Therneau TM, Beutler AS. SERE: single-parameter quality control and sample comparison for RNA-Seq. BMC Genomics. 2012; 13:524. Epub 2012 Oct 03.
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  21. Pleticha J, Maus TP, Jeng-Singh C, Marsh MP, Al-Saiegh F, Christner JA, Lee KH, Beutler AS. Pig lumbar spine anatomy and imaging-guided lateral lumbar puncture: a new large animal model for intrathecal drug delivery. J Neurosci Methods. 2013 May 30; 216(1):10-5. Epub 2013 Mar 19.
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  22. Banck MS, Kanwar R, Kulkarni AA, Boora GK, Metge F, Kipp BR, Zhang L, Thorland EC, Minn KT, Tentu R, Eckloff BW, Wieben ED, Wu Y, Cunningham JM, Nagorney DM, Gilbert JA, Ames MM, Beutler AS. The genomic landscape of small intestine neuroendocrine tumors. J Clin Invest. 2013 Jun; 123(6):2502-8. Epub 2013 May 15.
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  23. Francis JM, Kiezun A, Ramos AH, Serra S, Pedamallu CS, Qian ZR, Banck MS, Kanwar R, Kulkarni AA, Karpathakis A, Manzo V, Contractor T, Philips J, Nickerson E, Pho N, Hooshmand SM, Brais LK, Lawrence MS, Pugh T, McKenna A, Sivachenko A, Cibulskis K, Carter SL, Ojesina AI, Freeman S, Jones RT, Voet D, Saksena G, Auclair D, Onofrio R, Shefler E, Sougnez C, Grimsby J, Green L, Lennon N, Meyer T, Caplin M, Chung DC, Beutler AS, Ogino S, Thirlwell C, Shivdasani R, Asa SL, Harris CR, Getz G, Kulke M, Meyerson M. Carter SL, Ojesina AI, Freeman S, Jones RT, Voet D, Saksena G, Auclair D, Onofrio R, Shefler E, Sougnez C, Grimsby J, Green L, Lennon N, Meyer T, Caplin M, Chung DC, Beutler AS, Ogino S, Thirlwell C, Shivdasani R, Asa SL, Harris CR, Getz G, Kulke M, et Somatic mutation of CDKN1B in small intestine neuroendocrine tumors. Nat Genet. 2013; 45(12):1483-6.
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  24. Banck MS, Beutler AS. Advances in small bowel neuroendocrine neoplasia. Curr Opin Gastroenterol. 2014 Mar; 30(2):163-7.
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  25. Pleticha J, Jeng-Singh C, Rezek R, Zaibak M, Beutler AS. Intraneural convection enhanced delivery of AAVrh20 for targeting primary sensory neurons. Mol Cell Neurosci. 2014 May; 60:72-80. Epub 2014 Apr 24.
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  26. Pleticha J, Maus TP, Christner JA, Marsh MP, Lee KH, Hooten WM, Beutler AS. Minimally invasive convection-enhanced delivery of biologics into dorsal root ganglia: validation in the pig model and prospective modeling in humans. Technical note. J Neurosurg. 2014 Oct; 121(4):851-8. Epub 2014 Jul 04.
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  27. Beutler AS, Kulkarni AA, Kanwar R, Klein CJ, Therneau TM, Qin R, Banck MS, Boora GK, Ruddy KJ, Wu Y, Smalley RL, Cunningham JM, Le-Lindqwister NA, Beyerlein P, Schroth GP, Windebank AJ, Zuchner S, Loprinzi CL. Sequencing of Charcot-Marie-Tooth disease genes in a toxic polyneuropathy. Ann Neurol. 2014 Nov; 76(5):727-37. Epub 2014 Sep 17.
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  28. Pleticha J, Heilmann LF, Evans CH, Asokan A, Samulski RJ, Beutler AS. Preclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs. Mol Pain. 2014; 10:54. Epub 2014 Sep 02.
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  29. Pleticha J, Malkmus SA, Heilmann LF, Veesart SL, Rezek R, Xu Q, Yaksh TL, Beutler AS. High cerebrospinal fluid levels of interleukin-10 attained by AAV in dogs. Gene Ther. 2015 Feb; 22(2):202-8. Epub 2014 Oct 30.
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  30. Golzenleuchter M , Kanwar R , Zaibak M , Al Saiegh F , Hartung T , Klukas J , Smalley RL , Cunningham JM , Figueroa ME , Schroth GP , Therneau TM , Banck MS , Beutler AS . Plasticity of DNA methylation in a nerve injury model of pain. Epigenetics 2015; 10 (3):200-12
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  31. Boora GK, Kanwar R, Kulkarni AA, Pleticha J, Ames M, Schroth G, Beutler AS, Banck MS. Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines. Cancer Genet 2015 Jul-Aug; 208 (7-8):374-81 Epub 2015 Apr 14
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  32. Boora GK , Kulkarni AA , Kanwar R , Beyerlein P , Qin R , Banck MS , Ruddy KJ , Pleticha J , Lynch CA , Behrens RJ , Zuchner S , Loprinzi CL , Beutler AS . Association of the Charcot-Marie-Tooth disease gene ARHGEF10 with paclitaxel induced peripheral neuropathy in NCCTG N08CA (Alliance). J Neurol Sci 2015 Oct 15; 357 (1-2):35-40 Epub 2015 June 27
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  33. Pachman DR , Qin R , Seisler DK , Smith EM , Beutler AS , Ta LE , Lafky JM , Wagner-Johnston ND , Ruddy KJ , Dakhil S , Staff NP , Grothey A , Loprinzi CL . Clinical Course of Oxaliplatin-Induced Neuropathy: Results From the Randomized Phase III Trial N08CB (Alliance). J Clin Oncol 2015 Oct 20; 33 (30):3416-22 Epub 2015 Aug 17
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  34. Pachman DR, Ruddy K, Sangaralingham LR, Grothey A, Shah ND, Beutler AS, Hubbard JM, Loprinzi CL. Calcium and Magnesium Use for Oxaliplatin-Induced Neuropathy: A Case Study to Assess How Quickly Evidence Translates Into Practice. J Natl Compr Canc Netw. 2015 Sep; 13(9):1097-101.
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  35. Majithia N , Temkin SM , Ruddy KJ , Beutler AS , Hershman DL , Loprinzi CL . National Cancer Institute-supported chemotherapy-induced peripheral neuropathy trials: outcomes and lessons. Support Care Cancer 2016 Mar; 24 (3):1439-47 Epub 2015 Dec 19
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  36. Boora GK , Kanwar R , Kulkarni AA , Abyzov A , Sloan J , Ruddy KJ , Banck MS , Loprinzi CL , Beutler AS . Testing of candidate single nucleotide variants associated with paclitaxel neuropathy in the trial NCCTG N08C1 (Alliance). Cancer Med 2016 Apr; 5 (4):631-9 Epub 2016 Jan 14
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  37. Baheti S , Kanwar R , Goelzenleuchter M , Kocher JP , Beutler AS , Sun Z . Targeted alignment and end repair elimination increase alignment and methylation measure accuracy for reduced representation bisulfite sequencing data. BMC Genomics 2016; 17 (1):149 Epub 2016 Feb 27
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  38. Podratz JL , Kulkarni A , Pleticha J , Kanwar R , Beutler AS , Staff NP , Windebank AJ . Neurotoxicity to DRG neurons varies between rodent strains treated with cisplatin and bortezomib. J Neurol Sci 2016 Mar 15; 362:131-5 Epub 2015 Dec 28
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  39. Majithia N , Smith TJ , Coyne PJ , Abdi S , Pachman DR , Lachance D , Shelerud R , Cheville A , Basford JR , Farley D , O'Neill C , Ruddy KJ , Sparadeo F , Beutler A , Loprinzi CL . Scrambler Therapy for the management of chronic pain. Support Care Cancer 2016 Jun; 24 (6):2807-14 Epub 2016 Apr 04
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  40. Pleticha J , Maus TP , Beutler AS . Future Directions in Pain Management: Integrating Anatomically Selective Delivery Techniques With Novel Molecularly Selective Agents. Mayo Clin Proc 2016 Apr; 91 (4):522-33
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