Publications

  1. Painter MM, Morrison JH, Zoecklein LJ, Rinkoski TA, Watzlawik JO, Papke LM, Warrington AE, Bieber AJ, Matchett WE, Turkowski KL, Poeschla EM, Rodriguez M. Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity. PLoS Pathog 2015 Dec; 11 (12):e1005311 Epub 2015 Dec 03
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  2. Grahn PJ, Lee KH, Kasasbeh A, Mallory GW, Hachmann JT, Dube JR, Kimble CJ, Lobel DA, Bieber A, Jeong JH, Bennet KE, Lujan JL. Wireless control of intraspinal microstimulation in a rodent model of paralysis. J Neurosurg 2015 Jul; 123 (1):232-42 Epub 2014 Dec 05
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  3. Paek SB, Min HK, Kim I, Knight EJ, Baek JJ, Bieber AJ, Lee KH, Chang SY. Frequency-dependent functional neuromodulatory effects on the motor network by ventral lateral thalamic deep brain stimulation in swine. Neuroimage 2015 Jan 15; 105:181-8 Epub 2014 Oct 14
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  4. Kim I, Paek S, Nelson BD, Knight EJ, Marsh MP, Bieber AJ, Bennet KE, Lee KH. Implementation of a chronic unilateral intraparenchymal drug delivery system in a swine model. J Neurosci Methods 2014 Apr 30; 227:29-34 Epub 2014 Jan 31
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  5. Grahn PJ, Mallory GW, Khurram OU, Berry BM, Hachmann JT, Bieber AJ, Bennet KE, Min HK, Chang SY, Lee KH, Lujan JL. A neurochemical closed-loop controller for deep brain stimulation: toward individualized smart neuromodulation therapies. Front Neurosci 2014; 8:169 Epub 2014 June 25
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  6. Johnson HL, Hanson LM, Chen Y, Bieber AJ, Buono RJ, Ferraro TN, Pirko I, Johnson AJ. Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood-brain barrier disruption. BMC Genomics 2013 Oct 03; 14:678
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  7. Xu X, Denic A, Warrington AE, Bieber AJ, Rodriguez M. Therapeutics to promote CNS repair: a natural human neuron-binding IgM regulates membrane-raft dynamics and improves motility in a mouse model of multiple sclerosis. J Clin Immunol 2013 Jan; 33 Suppl 1:S50-6 Epub 2012 Sept 19
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  8. Ta LE, Schmelzer JD, Bieber AJ, Loprinzi CL, Sieck GC, Brederson JD, Low PA, Windebank AJ. A novel and selective poly (ADP-ribose) polymerase inhibitor ameliorates chemotherapy-induced painful neuropathy. PLoS One 2013; 8 (1):e54161 Epub 2013 Jan 10
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  9. Kasasbeh A, Lee K, Bieber A, Bennet K, Chang SY. Wireless neurochemical monitoring in humans. Stereotact Funct Neurosurg 2013; 91 (3):141-7 Epub 2013 Feb 27
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  10. Hachmann JT, Jeong JH, Grahn PJ, Mallory GW, Evertz LQ, Bieber AJ, Lobel DA, Bennet KE, Lee KH, Lujan JL. Large animal model for development of functional restoration paradigms using epidural and intraspinal stimulation. PLoS One 2013; 8 (12):e81443 Epub 2013 Dec 05
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  11. Denic A, Pirko I, Wootla B, Bieber A, Macura S, Rodriguez M. Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis. Brain Pathol 2012 Sep; 22 (5):698-708 Epub 2012 Mar 08
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  12. Xu X, Warrington AE, Wright BR, Bieber AJ, Van Keulen V, Pease LR, Rodriguez M. A human IgM signals axon outgrowth: coupling lipid raft to microtubules. J Neurochem 2011 Oct; 119 (1):100-12 Epub 2011 Sept 01
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  13. Denic A, Zoecklein L, Kerkvliet J, Papke L, Edukulla R, Warrington A, Bieber A, Pease LR, David CS, Rodriguez M. Transgenic expression of viral capsid proteins predisposes to axonal injury in a murine model of multiple sclerosis. Brain Pathol 2011 Sep; 21 (5):501-15 Epub 2011 Feb 11
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  14. Wootla B, Lacroix-Desmazes S, Warrington AE, Bieber AJ, Kaveri SV, Rodriguez M. Autoantibodies with enzymatic properties in human autoimmune diseases. J Autoimmun 2011 Sep; 37 (2):144-50 Epub 2011 May 31
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  15. Podratz JL, Staff NP, Froemel D, Wallner A, Wabnig F, Bieber AJ, Tang A, Windebank AJ. Drosophila melanogaster: a new model to study cisplatin-induced neurotoxicity. Neurobiol Dis 2011 Aug; 43 (2):330-7 Epub 2011 Apr 15
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  16. Xu X, Warrington AE, Bieber AJ, Rodriguez M. Enhancing CNS repair in neurological disease: challenges arising from neurodegeneration and rewiring of the network. CNS Drugs 2011 Jul; 25 (7):555-73
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  17. Denic A, Johnson AJ, Bieber AJ, Warrington AE, Rodriguez M, Pirko I. The relevance of animal models in multiple sclerosis research. Pathophysiology 2011 Feb; 18 (1):21-9
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  18. Wootla B, Denic A, Keegan BM, Winters JL, Astapenko D, Warrington AE, Bieber AJ, Rodriguez M. Evidence for the role of B cells and immunoglobulins in the pathogenesis of multiple sclerosis. Neurol Res Int 2011; 2011:780712 Epub 2011 Sept 22
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  19. Ta LE, Bieber AJ, Carlton SM, Loprinzi CL, Low PA, Windebank AJ. Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice. Mol Pain 2010 Mar 05; 6:15
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  20. Bieber AJ, Suwansrinon K, Kerkvliet J, Zhang W, Pease LR, Rodriguez M. Allelic variation in the Tyk2 and EGF genes as potential genetic determinants of CNS repair. Proc Natl Acad Sci U S A 2010 Jan 12; 107 (2):792-7 Epub 2009 Dec 22
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  21. Kerkvliet J, Zoecklein L, Papke L, Denic A, Bieber AJ, Pease LR, David CS, Rodriguez M. Transgenic expression of the 3D polymerase inhibits Theiler's virus infection and demyelination. J Virol 2009 Dec; 83 (23):12279-89 Epub 2009 Sept 16
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  22. Denic A, Bieber A, Warrington A, Mishra PK, Macura S, Rodriguez M. Brainstem 1H nuclear magnetic resonance (NMR) spectroscopy: marker of demyelination and repair in spinal cord. Ann Neurol 2009 Oct; 66 (4):559-64
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  23. Bieber AJ. Genetic analysis of CNS remyelination. Curr Top Microbiol Immunol 2008; 318:177-92
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  24. Warrington AE, Bieber AJ, Ciric B, Pease LR, Van Keulen V, Rodriguez M. A recombinant human IgM promotes myelin repair after a single, very low dose. J Neurosci Res. 2007 Apr; 85(5):967-76.
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  25. Suznovich CT, Pu R, Bieber AJ. CaM kinase II isoforms are expressed at lower levels in brains of shiverer mutants. J Mol Neurosci. 2007; 31(3):297-305.
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  26. Bieber AJ, Ure DR, Rodriguez M. Genetically dominant spinal cord repair in a murine. Model of chronic progressive multiple sclerosis. J Neuropathol Exp Neurol. 2005 Jan; 64(1):46-57.
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  27. Nelson AL, Bieber AJ, Rodriguez M. Contrasting murine models of MS. Int MS J 2004 Dec; 11 (3):95-9
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  28. Pirko I, Ciric B, Gamez J, Bieber AJ, Warrington AE, Johnson AJ, Hanson DP, Pease LR, Macura SI, Rodriguez M. A human antibody that promotes remyelination enters the CNS and decreases lesion load as detected by T2-weighted spinal cord MRI in a virus-induced murine model of MS. FASEB J. 2004 Oct; 18(13):1577-9. Epub 2004 Aug 19.
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  29. Warrington AE, Bieber AJ, Van Keulen V, Ciric B, Pease LR, Rodriguez M. Neuron-binding human monoclonal antibodies support central nervous system neurite extension. J Neuropathol Exp Neurol. 2004 May; 63(5):461-73.
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  30. Howe CL, Bieber AJ, Warrington AE, Pease LR, Rodriguez M. Antiapoptotic signaling by a remyelination-promoting human antimyelin antibody. Neurobiol Dis. 2004 Feb; 15(1):120-31.
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  31. Ciric B, Howe CL, Paz Soldan M, Warrington AE, Bieber AJ, Van Keulen V, Rodriguez M, Pease LR. Human monoclonal IgM antibody promotes CNS myelin repair independent of Fc function. Brain Pathol. 2003 Oct; 13(4):608-16.
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  32. Bieber AJ, Kerr S, Rodriguez M. Efficient central nervous system remyelination requires T cells. Ann Neurol. 2003 May; 53(5):680-4.
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  33. Paz Soldan MM, Warrington AE, Bieber AJ, Ciric B, Van Keulen V, Pease LR, Rodriguez M. Remyelination-promoting antibodies activate distinct Ca2+ influx pathways in astrocytes and oligodendrocytes: relationship to the mechanism of myelin repair. Mol Cell Neurosci. 2003 Jan; 22(1):14-24.
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  34. Mitsunaga Y, Ciric B, Van Keulen V, Warrington AE, Paz Soldan M, Bieber AJ, Rodriguez M, Pease LR. Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic-progressive demyelinating disease. FASEB J. 2002 Aug; 16(10):1325-7. Epub 2002 Jun 21.
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  35. Bieber AJ, Warrington A, Asakura K, Ciric B, Kaveri SV, Pease LR, Rodriguez M. Human antibodies accelerate the rate of remyelination following lysolecithin-induced demyelination in mice. Glia. 2002 Mar 1; 37(3):241-9.
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  36. Bieber AJ, Warrington A, Pease LR, Rodriguez M. Humoral autoimmunity as a mediator of CNS repair. Trends Neurosci. 2001 Nov; 24(11 Suppl):S39-44.
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  37. Warrington AE, Bieber AJ, Ciric B, Van Keulen V, Pease LR, Mitsunaga Y, Paz Soldan MM, Rodriguez M. Immunoglobulin-mediated CNS repair. J Allergy Clin Immunol. 2001 Oct; 108(4 Suppl):S121-5.
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  38. Bieber A, Asakura K, Warrington A, Kaveri SV, Rodriguez M. Antibody-mediated remyelination: relevance to multiple sclerosis. Mult Scler. 2000 Oct 6; (Suppl 2):S1-5, discussion S33.
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  39. Warrington AE, Asakura K, Bieber AJ, Ciric B, Van Keulen V, Kaveri SV, Kyle RA, Pease LR, Rodriguez M. Human monoclonal antibodies reactive to oligodendrocytes promote remyelination in a model of multiple sclerosis. Proc Natl Acad Sci U S A 2000 Jun 6; 97 (12):6820-5
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  40. Wang YE, Chandler R, Lau P, Bieber AJ. Drosophila nerve cord culture: a tool for studying neural development. J Neurosci Methods. 1998 Nov 1; 85(1):21-6.
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  41. Hall SG, Bieber AJ. Mutations in the Drosophila neuroglian cell adhesion molecule affect motor neuron pathfinding and peripheral nervous system patterning. J Neurobiol. 1997 Mar; 32(3):325-40.
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  42. Hortsch M, Wang YM, Marikar Y, Bieber AJ. The cytoplasmic domain of the drosophila cell adhesion molecule neuroglian is not essential for its homophilic adhesive properties in S2 cells. J Biol Chem. 1995 Aug 11; 270(32):18809-17.
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  43. Clark HF, Brentrup D, Schneitz K, Bieber A, Goodman C, Noll M. Dachsous encodes a member of the cadherin superfamily that controls imaginal disc morphogenesis in Drosophila. Genes Dev. 1995 Jun 15; 9(12):1530-42.
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  44. Huber AH, Wang YM, Bieber AJ, Bjorkman PJ. Crystal structure of tandem type III fibronectin domains from drosophila neuroglian at 2.0 A. Neuron. 1994 Apr; 12(4):717-31.
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  45. Hortsch M, Patel NH, Bieber AJ, Traquina ZR, Goodman CS. Drosophila neurotactin, a surface glycoprotein with homology to serine esterases, is dynamically expressed during embryogenesis. Development. 1990 Dec; 110(4):1327-40.
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  46. Elkins T, Hortsch M, Bieber AJ, Snow PM, Goodman CS. Drosophila fasciclin I is a novel homophilic adhesion molecule that along with fasciclin III can mediate cell sorting. J Cell Biol. 1990 May; 110(5):1825-32.
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  47. Hortsch M, Bieber AJ, Patel NH, Goodman CS. Differential splicing generates a nervous system-specific form of drosophila neuroglian. Neuron. 1990 May; 4(5):697-709.
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  48. Snow PM, Bieber AJ, Goodman CS. Fasciclin III: a novel homophilic adhesion molecule in drosophila. Cell. 1989 Oct 20; 59(2):313-23.
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  49. Bieber AJ, Snow PM, Hortsch M, Patel NH, Jacobs JR, Traquina ZR, Schilling J, Goodman CS. Drosophila neuroglian: a member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1. Cell. 1989; 59:447-60.
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  50. Mahmoud IY, Cyrus RV, Woller MJ, Bieber A. Development of the ovarian follicles in relation to changes in plasma parameters and 5 delta,3 beta-HSD in snapping turtle, chelydra serpentina. Comp Biochem Physiol. 1985; 82:131-6.