Publications

  1. Phillips-Krawczak CA, Singla A, Starokadomskyy P, Deng Z, Osborne DG, Li H, Dick CJ, Gomez TS, Koenecke M, Zhang JS, Dai H, Sifuentes-Dominguez LF, Geng LN, Kaufmann SH, Hein MY, Wallis M, McGaughran J, Gecz J, van de Sluis B, Billadeau DD, Burstein E. COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A. Mol Biol Cell. 2014 Oct 29.
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  2. Meng XW, Koh BD, Zhang JS, Flatten KS, Schneider PA, Billadeau DD, Hess AD, Smith BD, Karp JE, Kaufmann SH. Poly(ADP-ribose) polymerase inhibitors sensitize cancer cells to death receptor-mediated apoptosis by enhancing death receptor expression. J Biol Chem. 2014 Jul 25; 289(30):20543-58.
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  3. Baumgart S, Chen NM, Siveke JT, Konig A, Zhang JS, Singh SK, Wolf E, Bartkuhn M, Esposito I, Hessmann E, Reinecke J, Nikorowitsch J, Brunner M, Singh G, Fernandez-Zapico ME, Smyrk T, Bamlet WR, Eilers M, Neesse A, Gress TM, Billadeau DD, Tuveson D, Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D. Cancer Discov. 2014 Jun; 4(6):688-701. Epub 2014 Apr 02.
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  4. Herreros-Villanueva M, Bujanda L, Billadeau DD, Zhang JS. Embryonic stem cell factors and pancreatic cancer. World J Gastroenterol. 2014 Mar 7; 20(9):2247-54.
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  5. Zhang JS, Herreros-Vilanueva M, Koenig A, Deng Z, de Narvajas AA, Gomez TS, Meng X, Bujanda L, Ellenrieder V, Li XK, Kaufmann SH, Billadeau DD. Differential activity of GSK-3 isoforms regulates NF-kappaB and TRAIL- or TNFalpha induced apoptosis in pancreatic cancer cells. Cell Death Dis. 2014; 5:e1142. Epub 2014 Mar 27.
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  6. Artal-Martinez de Narvajas A, Gomez TS, Zhang JS, Mann AO, Taoda Y, Gorman JA, Herreros-Villanueva M, Gress TM, Ellenrieder V, Bujanda L, Kim DH, Kozikowski AP, Koenig A, Billadeau DD. Epigenetic regulation of autophagy by the methyltransferase G9a. Mol Cell Biol. 2013 Oct; 33(20):3983-93. Epub 2013 Aug 05.
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  7. Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R. Kruppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young. J Biol Chem. 2013 Jun 14; 288(24):17745-58. Epub 2013 Apr 15.
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  8. Herreros-Villanueva M, Zhang JS, Koenig A, Abel EV, Smyrk TC, Bamlet WR, de Narvajas AA, Gomez TS, Simeone DM, Bujanda L, Billadeau DD. SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells. Oncogenesis. 2013; 2:e61. Epub 2013 Aug 05.
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  9. Hu Z, Gu Y, Han B, Zhang J, Li Z, Tian K, Young CY, Yuan H. Knockdown of AGR2 induces cellular senescence in prostate cancer cells. Carcinogenesis. 2012 Jun; 33(6):1178-86. Epub 2012 Mar 31.
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  10. Daftary GS, Lomberk GA, Buttar NS, Allen TW, Grzenda A, Zhang J, Zheng Y, Mathison AJ, Gada RP, Calvo E, Iovanna JL, Billadeau DD, Prendergast FG, Urrutia R. Detailed structural-functional analysis of the Kruppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology. J Biol Chem. 2012 Mar 2; 287(10):7010-25. Epub 2011 Dec 27.
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  11. Baumgart S, Glesel E, Singh G, Chen NM, Reutlinger K, Zhang J, Billadeau DD, Fernandez-Zapico ME, Gress TM, Singh SK, Ellenrieder V. Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer. Gastroenterology. 2012 Feb; 142(2):388-98.e1-7. Epub 2011 Nov 10.
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  12. Meng XW, Peterson KL, Dai H, Schneider P, Lee SH, Zhang JS, Koenig A, Bronk S, Billadeau DD, Gores GJ, Kaufmann SH. High cell surface death receptor expression determines type I versus type II signaling. J Biol Chem. 2011 Oct 14; 286(41):35823-33. Epub 2011 Aug 24.
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  13. Zhang JS, Koenig A, Harrison A, Ugolkov AV, Fernandez-Zapico ME, Couch FJ, Billadeau DD. Mutant K-Ras increases GSK-3beta gene expression via an ETS-p300 transcriptional complex in pancreatic cancer. Oncogene. 2011 Aug 25; 30(34):3705-15. Epub 2011 Mar 28.
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  14. Zhang JS, Koenig A, Young C, Billadeau DD. GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration. Mol Biol Cell. 2011 Jun 15; 22(12):2119-30. Epub 2011 Apr 20.
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  15. He R, Chen Y, Chen Y, Ougolkov AV, Zhang JS, Savoy DN, Billadeau DD, Kozikowski AP. Synthesis and biological evaluation of triazol-4-ylphenyl-bearing histone deacetylase inhibitors as anticancer agents. J Med Chem. 2010 Feb 11; 53(3):1347-56.
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  16. Grzenda A, Lomberk G, Zhang JS, Urrutia R. Sin3: master scaffold and transcriptional corepressor. Biochim Biophys Acta. 2009 Jun-Aug; 1789(6-8):443-50. Epub 2009 Jun 06.
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  17. Vanaja DK, Grossmann ME, Cheville JC, Gazi MH, Gong A, Zhang JS, Ajtai K, Burghardt TP, Young CY. PDLIM4, an actin binding protein, suppresses prostate cancer cell growth. Cancer Invest. 2009 Mar; 27(3):264-72.
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  18. Wang N, Zheng Q, Zhang JS, Zhao Y. Molecular cloning and characterization of a novel mouse actin-binding protein Zfp185. J Mol Histol. 2008 Jun; 39(3):295-302. Epub 2008 Feb 01.
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  19. Wang N, Zhang JS, Zheng Q, Zhao Y. The unique localization of ZFP185 at uropod of mouse T lymphocytes. Scand J Immunol. 2008 Apr; 67(4):340-4.
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  20. Zhang JS, Gong A, Young CY. ZNF185, an actin-cytoskeleton-associated growth inhibitory LIM protein in prostate cancer. Oncogene. 2007 Jan 4; 26(1):111-22. Epub 2006 Jun 26.
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  21. Zhang JS, Gong A, Cheville JC, Smith DI, Young CY. AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer. Genes Chromosomes Cancer. 2005 Jul; 43(3):249-59.
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  22. Pan Y, Zhang JS, Gazi MH, Young CY. The cyclooxygenase 2-specific nonsteroidal anti-inflammatory drugs celecoxib and nimesulide inhibit androgen receptor activity via induction of c-Jun in prostate cancer cells. Cancer Epidemiol Biomarkers Prev. 2003 Aug; 12(8):769-74.
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  23. Pang YP, Kumar GA, Zhang JS, Urrutia R. Differential binding of Sin3 interacting repressor domains to the PAH2 domain of Sin3A. FEBS Lett. 2003 Jul 31; 548(1-3):108-12.
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  24. Jiang B, Zhang JS, Du JG, Urrutia R, Barnard J. Growth inhibitory signalling by TGF beta is blocked in Ras-transformed intestinal epithelial cells at a post-receptor locus. Cell Signal. 2003 Jul; 15(7):699-708.
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  25. Liu J, Zhang JS, Young CYF, Kao PC. Polymorphisms of prostate-specific antigen gene promoter: Determination from cord blood collected on filter paper. Ann Clin Lab Sci. 2003 Fal; 33(4):429-34.
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  26. Kaczynski JA, Conley AA, Fernandez Zapico M, Delgado SM, Zhang JS, Urrutia R. Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter. Biochem J. 2002 Sep 15; 366(Pt 3):873-82.
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  27. Ellenrieder V, Zhang JS, Kaczynski J, Urrutia R. Signaling disrupts mSin3A binding to the Mad1-like Sin3-interacting domain of TIEG2, an Sp1-like repressor. EMBO J. 2002 May 15; 21(10):2451-60.
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  28. Kaczynski J, Zhang JS, Ellenrieder V, Conley A, Duenes T, Kester H, van Der Burg B, Urrutia R. The Sp1-like protein BTEB3 inhibits transcription via the basic transcription element box by interacting with mSin3A and HDAC-1 co-repressors and competing with Sp1. J Biol Chem. 2001 Sep 28; 276(39):36749-56. Epub 2001 Jul 27.
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  29. Zhu W, Zhang JS, Young CY. Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP. Carcinogenesis. 2001 Sep; 22(9):1399-403.
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  30. Chung BH, Mitchell SH, Zhang JS, Young CY. Effects of docosahexaenoic acid and eicosapentaenoic acid on androgen-mediated cell growth and gene expression in LNCaP prostate cancer cells. Carcinogenesis. 2001 Aug; 22(8):1201-6.
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  31. Zhang JS, Moncrieffe MC, Kaczynski J, Ellenrieder V, Prendergast FG, Urrutia R. A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A. Mol Cell Biol. 2001 Aug; 21(15):5041-9.
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  32. Zhang JS, Wang L, Huang H, Nelson M, Smith DI. Keratin 23 (K23), a novel acidic keratin, is highly induced by histone deacetylase inhibitors during differentiation of pancreatic cancer cells. Genes Chromosomes Cancer. 2001 Feb; 30(2):123-35.
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  33. Wang L, Darling J, Zhang JS, Liu W, Qian J, Bostwick D, Hartmann L, Jenkins R, Bardenhauer W, Schutte J, Opalka B, Smith DI. Loss of expression of the DRR 1 gene at chromosomal segment 3p21.1 in renal cell carcinoma. Genes Chromosomes Cancer. 2000 Jan; 27(1):1-10.
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  34. Huang H, Reed CP, Zhang JS, Shridhar V, Wang L, Smith DI. Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. Cancer Res. 1999 Jun 15; 59(12):2981-8.
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  35. Yang J, Zhang J, Lu S. [Acquirement and identification of a novel intron 1 of human Na(+)-K(+)-exchanging ATPase alpha 1 subunit gene]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1999 Jun; 21(3):159-65.
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  36. Wang L, Darling J, Zhang JS, Huang H, Liu W, Smith DI. Allele-specific late replication and fragility of the most active common fragile site, FRA3B. Hum Mol Genet. 1999 Mar; 8(3):431-7.
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  37. Zhang JS, Nelson M, Wang L, Liu W, Qian CP, Shridhar V, Urrutia R, Smith DI. Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin. Genomics. 1998 Nov 15; 54(1):149-54.
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  38. Zhang JS, Nelson M, McIver B, Hay ID, Goellner JR, Grant CS, Eberhardt NL, Smith DI. Differential loss of heterozygosity at 7q31.2 in follicular and papillary thyroid tumors. Oncogene. 1998 Aug 13; 17(6):789-93.
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  39. Wang L, Darling J, Zhang JS, Qian CP, Hartmann L, Conover C, Jenkins R, Smith DI. Frequent homozygous deletions in the FRA3B region in tumor cell lines still leave the FHIT exons intact. Oncogene. 1998 Feb 5; 16(5):635-42.
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  40. Zhang J, Ding F, Wang X. [Expression and loss of heterozygosity of DCC gene in human lung cancer]. Zhonghua Yi Xue Za Zhi. 1995 Apr; 75(4):211-3, 254-5.
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  41. Zhang JS, Nakatsugawa S, Niwa O, Ju GZ, Liu SZ. Ionizing radiation-induced IL-1 alpha, IL-6 and GM-CSF production by human lung cancer cells. Chin Med J (Engl). 1994 Sep; 107(9):653-7.
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  42. Zhang JS, Nakatsugawa S, Ishii Y, Ju GZ, Liu SZ. Experimental radiotherapy and metastasis of human lung cancer xenografts in nude mice. Chin Med J (Engl). 1994 Jul; 107(7):491-5.
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  43. Svistuneko DA, Ju GZ, Wei J, Zhang JS, Liu SZ. EPR study of mouse tissues in search for adaptive responses to low level whole-body X-irradiation. Int J Radiat Biol. 1992 Sep; 62(3):327-36.
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  44. Ju GZ QJ, Zhang JS, Zhang J, Liu SZ. Effects of MX912, a Warm extracts, on the immune system of irradiated tumor-bearing mouse. Chinese J of Clinical Oncology. 1991; 8(3):174-9.