Publications

  1. Kwan A, Abraham RS, Currier R, Brower A, Andruszewski K, Abbott JK, Baker M, Ballow M, Bartoshesky LE, Bonilla FA, Brokopp C, Brooks E, Caggana M, Celestin J, Church JA, Comeau AM, Connelly JA, Cowan MJ, Cunningham-Rundles C, Dasu T, Dave N, De La Morena Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States. JAMA. 2014 Aug 20; 312(7):729-38.
    View PubMed
  2. Tebo A, Detrick B, Hamilton R, Khanolkar A, O'Gorman M, Schmitz J, Abraham R. Clinical Laboratory Immunology: An indispensable player in laboratory medicine. American Journal of Clinical Pathology , In press. 2014.
  3. Urm SH, Yun HD, Fenta YA, Yoo KH, Abraham RS, Hagan J, Juhn YJ. Asthma and risk of selective IgA deficiency or common variable immunodeficiency: a population-based case-control study. Mayo Clin Proc. 2013 Aug; 88(8):813-21.
    View PubMed
  4. Gustafson MP, Lin Y, LaPlant B, Liwski CJ, Maas ML, League SC, Bauer PR, Abraham RS, Tollefson MK, Kwon ED, Gastineau DA, Dietz AB. Immune monitoring using the predictive power of immune profiles. Journal for ImmunoTherapy of Cancer. 2013 Jun 27; 1(7).
  5. Kudva YC, Erickson JR, Parsaik A, Rostambeigi N, Thapa P, Abraham RS. Comprehensive immune monitoring reveals profound immunological changes in pancreas after kidney (PAK) transplant recipients. Hum Immunol. 2013 Jun; 74(6):738-45. Epub 2013 Mar 07.
    View PubMed
  6. Juskewitch JE, Enders FT, Abraham RS, Huskins WC. Novel infrastructure for sepsis biomarker research in critically ill neonates and children. Clin Transl Sci. 2013 Feb; 6(1):21-5. Epub 2013 Jan 14.
    View PubMed
  7. Tschumper RC, Dispenzieri A, Abraham RS, Henderson KJ, Jelinek DF. Molecular analysis of immunoglobulin genes reveals frequent clonal relatedness in double monoclonal gammopathies. Blood Cancer J. 2013; 3:e112. Epub 2013 Apr 19.
    View PubMed
  8. Trushin SA, Carena AA, Bren GD, Rizza SA, Dong X, Abraham RS, Badley AD. SDF-1alpha degrades whereas glycoprotein 120 upregulates Bcl-2 interacting mediator of death extralong isoform: implications for the development of T cell memory. J Immunol. 2012 Aug 15; 189(4):1835-42. Epub 2012 Jul 16.
    View PubMed
  9. Abraham RS. Relevance of antibody testing in patients with recurrent infections. J Allergy Clin Immunol. 2012 Aug; 130(2):558-9.e6.
    View PubMed
  10. Podjasek JC, Abraham RS. Autoimmune cytopenias in common variable immunodeficiency. Front Immunol. 2012; 3:189. Epub 2012 Jul 24.
    View PubMed
  11. Katoh N, Poshusta TL, Manske MK, Dispenzieri A, Gertz MA, Abraham RS, Ramirez-Alvarado M. A reappraisal of immunoglobulin variable gene primers and its impact on assessing clonal relationships between PB B cells and BM plasma cells in AL amyloidosis. J Clin Immunol. 2011 Dec; 31(6):1029-37. Epub 2011 Sep 10.
    View PubMed
  12. Parsaik AK, Bhalla T, Dong M, Rostambeigi N, Dierkhising RA, Dean P, Abraham R, Prieto M, Kremers WK, Razonable RR, Kudva YC. Epidemiology of cytomegalovirus infection after pancreas transplantation. Transplantation. 2011 Nov 15; 92(9):1044-50.
    View PubMed
  13. Joshi AY, Abraham RS, Snyder MR, Boyce TG. Immune evaluation and vaccine responses in Down syndrome: evidence of immunodeficiency? Vaccine. 2011 Jul 12; 29(31):5040-6. Epub 2011 May 17.
    View PubMed
  14. Bellavia D, Abraham RS, Pellikka PA, Dispenzieri A, Burnett JC Jr, Al-Zahrani GB, Green TD, Manske MK, Gertz MA, Miller FA Jr, Abraham TP. Utility of Doppler myocardial imaging, cardiac biomarkers, and clonal immunoglobulin genes to assess left ventricular performance and stratify risk following peripheral blood stem cell transplantation in patients with systemic light chain amyloidosis (Al). J Am Soc Echocardiogr. 2011 Apr; 24(4):444-54. Epub 2011 Feb 18.
    View PubMed
  15. Abraham RS. Relevance of laboratory testing for the diagnosis of primary immunodeficiencies: a review of case-based examples of selected immunodeficiencies. Clin Mol Allergy. 2011; 9:6. Epub 2011 Apr 09.
    View PubMed
  16. Shah KM, Pratt EL, Al-Rahawan MM, Abraham RS. Novel combination of ITGB2 mutations causing leukocyte adhesion deficiency type 1 (LAD-1). Journal of Pediatric Infectious Diseases. 2011; 6(2):141-8.
  17. Fervenza FC, Abraham RS, Erickson SB, Irazabal MV, Eirin A, Specks U, Nachman PH, Bergstralh EJ, Leung N, Cosio FG, Hogan MC, Dillon JJ, Hickson LJ, Li X, Cattran DC, Mayo Nephrology Collaborative Group. Rituximab therapy in idiopathic membranous nephropathy: a 2-year study. Clin J Am Soc Nephrol. 2010 Dec; 5(12):2188-98. Epub 2010 Aug 12.
    View PubMed
  18. Rostambeigi N, Kudva YC, John S, Mailankody S, Pedersen RA, Dean PG, Prieto M, Cosio FG, Kremers WK, Walker RC, Abraham RS, Stegall MD. Epidemiology of infections requiring hospitalization during long-term follow-up of pancreas transplantation. Transplantation. 2010 May 15; 89(9):1126-33.
    View PubMed
  19. Dong X, Hoeltzle MV, Hagan JB, Park MA, Li JT, Abraham RS. Phenotypic and clinical heterogeneity associated with monoallelic TNFRSF13B-A181E mutations in common variable immunodeficiency. Hum Immunol. 2010 May; 71(5):505-11. Epub 2010 Mar 12.
    View PubMed
  20. Zuckerman NS, McCann KJ, Ottensmeier CH, Barak M, Shahaf G, Edelman H, Dunn-Walters D, Abraham RS, Stevenson FK, Mehr R. Ig gene diversification and selection in follicular lymphoma, diffuse large B cell lymphoma and primary central nervous system lymphoma revealed by lineage tree and mutation analyses. Int Immunol. 2010; 22(11):863-73.
  21. Cummins NW, Deziel PJ, Abraham RS, Razonable RR. Deficiency of cytomegalovirus (CMV)-specific CD8+ T cells in patients presenting with late-onset CMV disease several years after transplantation. Transpl Infect Dis. 2009 Feb; 11(1):20-7. Epub 2008 Sep 21.
    View PubMed
  22. Joshi AY, Iyer VN, Boyce TG, Hagan JB, Park MA, Abraham RS. Elevated serum immunoglobulin E (IgE): when to suspect hyper-IgE syndrome-A 10-year pediatric tertiary care center experience. Allergy Asthma Proc. 2009 Jan-Feb; 30(1):23-7.
    View PubMed
  23. Park MA, Li JT, Hagan JB, Maddox DE, Abraham RS. Common variable immunodeficiency: a new look at an old disease. Lancet. 2008 Aug 9; 372(9637):489-502.
    View PubMed
  24. Shepard BD, De Forni D, McNamara DR, Foli A, Rizza SA, Abraham RS, Knutson K, Wettstein PJ, Lori F, Badley AD. Beneficial effect of TRAIL on HIV burden, without detectable immune consequences. PLoS One. 2008; 3(8):e3096. Epub 2008 Aug 28.
    View PubMed
  25. Martin W, Abraham R, Shanafelt T, Clark RJ, Bone N, Geyer SM, Katzmann JA, Bradwell A, Kay NE, Witzig TE. Serum-free light chain-a new biomarker for patients with B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia. Transl Res. 2007 Apr; 149(4):231-5.
    View PubMed
  26. Abraham RS, Manske MK, Zuckerman NS, Sohni A, Edelman H, Shahaf G, Timm MM, Dispenzieri A, Gertz MA, Mehr R. Novel analysis of clonal diversification in blood B cell and bone marrow plasma cell clones in immunoglobulin light chain amyloidosis. J Clin Immunol. 2007 Jan; 27(1):69-87. Epub 2006 Dec 28.
    View PubMed
  27. Abraham RS, Manske MK, Sohni A, Zuckerman NS, Edelman H, Shahaf G, Timm MM, Dispenzieri A, Gertz MA, Mehr R. Graphical quantification of B cell lineage trees reveals clonal diversification in immunoglobulin light chain amyloidosis. J Clin Immun. 2007; 27(1):69-87.
  28. Katzmann JA, Dispenzieri A, Kyle RA, Snyder MR, Plevak MF, Larson DR, Abraham RS, Lust JA, Melton LJ 3rd, Rajkumar SV. Elimination of the need for urine studies in the screening algorithm for monoclonal gammopathies by using serum immunofixation and free light chain assays. Mayo Clin Proc. 2006 Dec; 81(12):1575-8.
    View PubMed
  29. Steiman-Shimony A, Edelman H, Hutzler A, Barak M, Zuckerman NS, Shahaf G, Dunn-Walters D, Stott DI, Abraham RS, Mehr R. Lineage tree analysis of immunoglobulin variable-region gene mutations in autoimmune diseases: chronic activation, normal selection. Cell Immunol. 2006 Dec; 244(2):130-6. Epub 2007 Apr 16.
    View PubMed
  30. Manske MK, Zuckerman NS, Timm MM, Maiden S, Edelman H, Shahaf G, Barak M, Dispenzieri A, Gertz MA, Mehr R, Abraham RS. Quantitative analysis of clonal bone marrow CD19+ B cells: use of B cell lineage trees to delineate their role in the pathogenesis of light chain amyloidosis. Clin Immunol. 2006 Jul; 120(1):106-20. Epub 2006 Mar 03.
    View PubMed
  31. Dispenzieri A, Lacy MQ, Katzmann JA, Rajkumar SV, Abraham RS, Hayman SR, Kumar SK, Clark R, Kyle RA, Litzow MR, Inwards DJ, Ansell SM, Micallef IM, Porrata LF, Elliott MA, Johnston PB, Greipp PR, Witzig TE, Zeldenrust SR, Russell SJ, Gastineau D, Gertz Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation. Blood. 2006 Apr 15; 107(8):3378-83. Epub 2006 Jan 05.
    View PubMed
  32. Steiman-Shimony A, Edelman H, Barak M, Shahaf G, Dunn-Walters D, Stott DI, Abraham RS, Mehr R. Immunoglobulin variable-region gene mutational lineage tree analysis: application to autoimmune diseases. Journal of Autoimmunity Reviews. 2006; 5:242-251.
  33. Katzmann JA, Abraham RS, Dispenzieri A, Lust JA, Kyle RA. Diagnostic performance of quantitative kappa and lambda free light chain assays in clinical practice. Clin Chem. 2005 May; 51(5):878-81.
    View PubMed
  34. Abraham RS, Ballman KV, Dispenzieri A, Grill DE, Manske MK, Price-Troska TL, Paz NG, Gertz MA, Fonseca R. Functional gene expression analysis of clonal plasma cells identifies a unique molecular profile for light chain amyloidosis. Blood. 2005 Jan 15; 105(2):794-803.
    View PubMed
  35. Abraham RS, Geyer SM, Ramirez-Alvarado M, Price-Troska TL, Gertz MA, Fonseca R. Analysis of somatic hypermutation and antigenic selection in the clonal B cell in immunoglobulin light chain amyloidosis (AL). J Clin Immunol. 2004 Jul; 24(4):340-53.
    View PubMed
  36. Bergen HR, Abraham RS, Johnson KL, Bradwell AR, Naylor S. Characterization of amyloidogenic immunoglobulin light chains directly from serum by on-line immunoaffinity isolation. Biomed Chromatogr. 2004 Apr; 18(3):191-201.
    View PubMed
  37. Abraham RS, Geyer SM, Price-Troska TL, Allmer C, Kyle RA, Gertz MA, Fonseca R. Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated amyloidosis (AL). Blood. 2003 May 15; 101(10):3801-8.
    View PubMed
  38. Abraham RS, Katzmann JA, Clark RJ, Bradwell AR, Kyle RA, Gertz MA. Quantitative analysis of serum free light chains - A new marker for the diagnostic evaluation of primary systemic amyloidosis. Am J Clin Pathol. 2003 Feb; 119(2):274-8.
    View PubMed
  39. Kudva YC, Rajagopalan G, Raju R, Abraham RS, Smart M, Hanson J, David CS. Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II. Hum Immunol. 2002 Nov; 63(11):987-99.
    View PubMed
  40. Abraham RS, Charlesworth MC, Owen BAL, Benson LM, Katzmann JA, Reeder CB, Kyle RA. Trimolecular complexes of lambda light chain dimers in serum of a patient with multiple myeloma. Clin Chem. 2002 Oct; 48(10):1805-11.
    View PubMed
  41. Katzmann JA, Clark RJ, Abraham RS, Bryant S, Lymp JF, Bradwell AR, Kyle RA. Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin Chem. 2002 Sep; 48(9):1437-44.
    View PubMed
  42. Abraham RS, Clark RJ, Bryant SC, Lymp JF, Larson T, Kyle RA, Katzmann JA. Correlation of serum immunoglobulin free light chain quantification with urinary Bence Jones protein in light chain myeloma. Clin Chem. 2002; 48(4):655-7.
    View PubMed
  43. Naumov YN, Bahjat KS, Gausling R, Abraham R, Exley MA, Koezuka Y, Balk SB, Strominger JL, Clare-Salzer M, Wilson SB. Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13838-43. Epub 2001 Nov 13.
    View PubMed
  44. Kudva YC, Deng YJ, Govindarajan R, Abraham RS, Marietta EV, Notkins AL, David CS. HLA-DQ8 transgenic and NOD mice recognize different epitopes within the cytoplasmic region of the tyrosine phosphatase-like molecule, IA-2. Hum Immunol. 2001 Oct; 62(10):1099-105.
    View PubMed
  45. Abraham RS, Wen L, Marietta EV, David CS. Type 1 diabetes-predisposing MHC alleles influence the selection of glutamic acid decarboxylase (GAD) 65-specific T cells in a transgenic model. J Immunol. 2001 Jan 15; 166(2):1370-9.
    View PubMed
  46. Abraham RS, Kudva YC, Wilson SB, Strominger JL, David CS. Co-expression of HLA DR3 and DQ8 results in the development of spontaneous insulitis and loss of tolerance to GAD65 in transgenic mice. Diabetes. 2000 Apr; 49(4):548-54.
    View PubMed
  47. Abraham RS, David CS. Identification of HLA-class-II-restricted epitopes of autoantigens in transgenic mice. Curr Opin Immunol. 2000 Feb; 12(1):122-9.
    View PubMed
  48. Das P, Abraham R, David C. HLA transgenic mice as models of human autoimmune diseases. Rev Immunogenet. 2000; 2(1):105-14.
    View PubMed
  49. Abraham RS, Wilson SB, de Souza NF Jr, Strominger JL, Munn SR, David CS. NOD background genes influence T cell responses to GAD 65 in HLA-DQ8 transgenic mice. Hum Immunol. 1999 Jul; 60(7):583-90.
    View PubMed
  50. Das P, Abraham RS, David CS. HLA transgenic mice as models of human autoimmune diseases. Reviews in Immunogenetics. 1999 2; 2:105-11.
  51. Abraham RS, Kudva YC, Wilson SB, Strominger JL, David CS. NOD background genes influence T cell responses to GAD 65 in HLA-DQ8 transgenic mice. Diabetes. 1999; 49:548-55.
  52. Singh N, Bhatia S, Abraham RS, Basu SK, George A, Bal V, Rath S. Modulation of T cell cytokine profiles and peptide-MHC complex availability in vivo by delivery to scavenger receptors via antigen maleylation. Journal of Immunology. 1998; 160:4869-880.
  53. Abraham RS, Choudhury A, Basu SK, Bal V, Rath S. Disruption of T cell tolerance by directing a self-antigen to macrophage-specific scavenger receptor. Journal of Immunology. 1997; 158:4029-35.
  54. Abraham RS, Singh N, Mukhopadhyay A, Basu S K, Bal V, Rath, S. Modulation of immunogenicity and antigenicity of proteins by maleylation to target scavenger receptors on macrophages. Journal of Immunology. 1995; 154:1-8.