Publications

  1. Abidi MZ, Sohail MR, Cummins N, Wilhelm M, Wengenack N, Brumble L, Shah H, Jane Hata D, McCullough A, Wendel A, Vikram HR, Kusne S, Litzow M, Letendre L, Lahr BD, Poeschla E, Walker RC. Stability in the cumulative incidence, severity and mortality of 101 cases of invasive mucormycosis in high-risk patients from 1995 to 2011: a comparison of eras immediately before and after the availability of voriconazole and echinocandin-amphotericin combination therapies. Mycoses. 2014 Jul 18.
    View PubMed
  2. Khare R, Gupta S, Arif S, Jentoft ME, Deziel PJ, Roden AC, Wilhelm MP, Razonable RR, Wengenack NL. Misidentification of Neosartorya pseudofischeri as Aspergillus fumigatus in a Lung Transplant Patient. J Clin Microbiol. 2014 Jul; 52(7):2722-5. Epub 2014 May 14.
    View PubMed
  3. Beam E, Vasoo S, Simner PJ, Rizzo M, Mason EL, Walker RC, Deml SM, Brown-Elliott BA, Wallace RJ Jr, Wengenack NL, Sia IG. Mycobacterium arupense Flexor Tenosynovitis: Case Report and Review of Antimicrobial Susceptibility Profiles for 40 Clinical Isolates. J Clin Microbiol. 2014 Jul; 52(7):2706-8. Epub 2014 Apr 30.
    View PubMed
  4. Buckwalter SP, Sloan LM, Cunningham SA, Espy MJ, Uhl JR, Jones MF, Vetter EA, Mandrekar J, Cockerill FR 3rd, Pritt BS, Patel R, Wengenack NL. Inhibition controls for qualitative real-time PCR assays: are they necessary for all specimen matrices? J Clin Microbiol. 2014 Jun; 52(6):2139-43. Epub 2014 Apr 16.
    View PubMed
  5. Simner PJ, Buckwalter SP, Uhl JR, Wengenack NL. Identification of Mycobacterium species and Mycobacterium tuberculosis complex resistance determinants by use of PCR-electrospray ionization mass spectrometry. J Clin Microbiol. 2013 Nov; 51(11):3492-8. Epub 2013 Aug 14.
    View PubMed
  6. Simner PJ, Buckwalter SP, Uhl JR, Wengenack NL, Pritt BS. Detection and identification of yeasts from formalin-fixed, paraffin-embedded tissue by use of PCR-electrospray ionization mass spectrometry. J Clin Microbiol. 2013 Nov; 51(11):3731-4. Epub 2013 Aug 28.
    View PubMed
  7. Ramanan P, Deziel PJ, Wengenack NL. Gordonia bacteremia. J Clin Microbiol. 2013 Oct; 51(10):3443-7. Epub 2013 Jul 24.
    View PubMed
  8. Mukhopadhyay S, Wilcox BE, Myers JL, Bryant SC, Buckwalter SP, Wengenack NL, Yi ES, Aughenbaugh GL, Specks U, Aubry MC. Pulmonary necrotizing granulomas of unknown cause: clinical and pathologic analysis of 131 patients with completely resected nodules. Chest. 2013 Sep; 144(3):813-24.
    View PubMed
  9. Simner PJ, Uhl JR, Hall L, Weber MM, Walchak RC, Buckwalter S, Wengenack NL. Broad-range direct detection and identification of fungi by use of the PLEX-ID PCR-electrospray ionization mass spectrometry (ESI-MS) system. J Clin Microbiol. 2013 Jun; 51(6):1699-706. Epub 2013 Mar 20.
    View PubMed
  10. Theel ES, Jespersen DJ, Iqbal S, Bestrom JE, Rollins LO, Misner LJ, Markley BJ, Mandrekar J, Baddour LM, Limper AH, Wengenack NL, Binnicker MJ. Detection of (1, 3)-beta-D-glucan in bronchoalveolar lavage and serum samples collected from immunocompromised hosts. Mycopathologia. 2013 Feb; 175(1-2):33-41 Epub 2012 Sep 1.
    View PubMed
  11. Wentworth AB, Drage LA, Wengenack NL, Wilson JW, Lohse CM. Increased incidence of cutaneous nontuberculous mycobacterial infection, 1980 to 2009: a population-based study. Mayo Clin Proc. 2013 Jan; 88(1):38-45. Epub 2012 Dec 04.
    View PubMed
  12. Sia IG, Buckwalter SP, Doerr KA, Lugos S, Kramer R, Orillaza-Chi R, Quelapio MI, Tupasi TE, Wengenack NL. Genotypic characteristics of Mycobacterium tuberculosis isolated from household contacts of tuberculosis patients in the Philippines. BMC Infect Dis. 2013; 13:571. Epub 2013 Dec 5
    View PubMed
  13. Anderson JH, Boyce TG, Wengenack NL, Driscoll CLW, Fischer PR. Mycobacterium abscessus infection of a cochlear implant insertion site. International Journal of Pediatric Otorhinolaryngology Extra. 2013; 8(4):122-4.
  14. Hall L, Jude KP, Clark SL, Dionne K, Merson R, Boyer A, Parrish NM, Wengenack NL. Evaluation of the Sensititre MycoTB plate for susceptibility testing of the Mycobacterium tuberculosis complex against first- and second-line agents. J Clin Microbiol. 2012 Nov; 50(11):3732-4. Epub 2012 Aug 15.
    View PubMed
  15. Theel ES, Schmitt BH, Hall L, Cunningham SA, Walchak RC, Patel R, Wengenack NL. Formic acid-based direct, on-plate testing of yeast and Corynebacterium species by Bruker Biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol. 2012 Sep; 50(9):3093-5 Epub 2012 Jul 3.
    View PubMed
  16. McTaggart LR, Wengenack NL, Richardson SE. Validation of the MycAssay Pneumocystis kit for detection of Pneumocystis jirovecii in bronchoalveolar lavage specimens by comparison to a laboratory standard of direct immunofluorescence microscopy, real-time PCR, or conventional PCR. J Clin Microbiol. 2012 Jun; 50(6):1856-9. Epub 2012 Mar 14.
    View PubMed
  17. Seah C, Richardson SE, Tsui G, Yu B, Thornback J, McTaggart L, Boggild A, Wengenack NL, Zhang SX. Comparison of the FXG: RESP (Asp+) real-time PCR assay with direct immunofluorescence and calcofluor white staining for the detection of Pneumocystis jirovecii in respiratory specimens. Med Mycol. 2012 Apr; 50(3):324-7. Epub 2011 Aug 23.
    View PubMed
  18. Conville PS, Brown-Elliott BA, Wallace RJ Jr, Witebsky FG, Koziol D, Hall GS, Killian SB, Knapp CC, Warshauer D, Van T, Wengenack NL, Deml S, Woods GL. Multisite reproducibility of the broth microdilution method for susceptibility testing of Nocardia species. J Clin Microbiol. 2012 Apr; 50(4):1270-80. Epub 2012 Jan 04.
    View PubMed
  19. Hall L, Le Febre KM, Deml SM, Wohlfiel SL, Wengenack NL. Evaluation of the Yeast Traffic Light PNA FISH probes for identification of Candida species from positive blood cultures. J Clin Microbiol. 2012 Apr; 50(4):1446-8. Epub 2012 Jan 11.
    View PubMed
  20. Brown-Elliott BA, Biehle J, Conville PS, Cohen S, Saubolle M, Sussland D, Wengenack N, Kriel K, Bridge L, McNulty S, Vasireddy R, Wallace RJ Jr. Sulfonamide resistance in isolates of Nocardia spp. from a US multicenter survey. J Clin Microbiol. 2012 Mar; 50(3):670-2. Epub 2011 Dec 14.
    View PubMed
  21. Ariza-Heredia EJ, Dababneh AS, Wilhelm MP, Wengenack NL, Razonable RR, Wilson JW. Mycobacterium wolinskyi: a case series and review of the literature. Diagn Microbiol Infect Dis. 2011 Dec; 71(4):421-7. Epub 2011 Sep 25.
    View PubMed
  22. Theel ES, Hall L, Mandrekar J, Wengenack NL. Dermatophyte identification using matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol. 2011 Dec; 49(12):4067-71. Epub 2011 Sep 28.
    View PubMed
  23. Santillan Salas CF, Joshi AY, Dhiman N, Banerjee R, Huskins WC, Wengenack NL, Henry NK. Fatal post-operative Trichoderma longibrachiatum mediastinitis and peritonitis in a paediatric patient with complex congenital cardiac disease on peritoneal dialysis. J Med Microbiol. 2011 Dec; 60(Pt 12):1869-71. Epub 2011 Jul 28.
    View PubMed
  24. Hage CA, Ribes JA, Wengenack NL, Baddour LM, Assi M, McKinsey DS, Hammoud K, Alapat D, Babady NE, Parker M, Fuller D, Noor A, Davis TE, Rodgers M, Connolly PA, El Haddad B, Wheat LJ. A multicenter evaluation of tests for diagnosis of histoplasmosis. Clin Infect Dis. 2011 Sep; 53(5):448-54. Epub 2011 Aug 02.
    View PubMed
  25. Babady NE, Buckwalter SP, Hall L, Le Febre KM, Binnicker MJ, Wengenack NL. Detection of Blastomyces dermatitidis and Histoplasma capsulatum from culture isolates and clinical specimens by use of real-time PCR. J Clin Microbiol. 2011 Sep; 49(9):3204-8. Epub 2011 Jul 13.
    View PubMed
  26. Doskaya M, Caner A, Degirmenci A, Wengenack NL, Yolasigmaz A, Turgay N, Ozensoy Toz S, Guruz Y. Degree and frequency of inhibition in a routine real-time PCR detecting Pneumocystis jirovecii for the diagnosis of Pneumocystis pneumonia in Turkey. J Med Microbiol. 2011 Jul; 60(Pt 7):937-44. Epub 2011 Apr 01.
    View PubMed
  27. Binnicker MJ, Popa AS, Catania J, Alexov M, Tsaras G, Lloyd F, Wengenack NL, Enzler MJ. Meningeal coccidioidomycosis diagnosed by real-time polymerase chain reaction analysis of cerebrospinal fluid. Mycopathologia. 2011 Apr; 171(4):285-9. Epub 2010 Oct 07.
    View PubMed
  28. Dhiman N, Hall L, Wohlfiel SL, Buckwalter SP, Wengenack NL. Performance and cost analysis of matrix-assisted laser desorption ionization-time of flight mass spectrometry for routine identification of yeast. J Clin Microbiol. 2011 Apr; 49(4):1614-6. Epub 2011 Jan 26.
    View PubMed
  29. Khoury NZ, Binnicker MJ, Wengenack NL, Aksamit TR, Buchta WG, Molella RG. Preemployment screening for tuberculosis in a large health care setting: comparison of the tuberculin skin test and a whole-blood interferon-gamma release assay. J Occup Environ Med. 2011 Mar; 53(3):290-3.
    View PubMed
  30. Wilson JW, Limper AH, Grys TE, Karre T, Wengenack NL, Binnicker MJ. Pneumocystis jirovecii testing by real-time polymerase chain reaction and direct examination among immunocompetent and immunosuppressed patient groups and correlation to disease specificity. Diagn Microbiol Infect Dis. 2011 Feb; 69(2):145-52.
    View PubMed
  31. Hall L, Jude KP, Clark SL, Wengenack NL. Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex for first and second line drugs by broth dilution in a microtiter plate format. J Vis Exp. 2011; (52). Epub 2011 Jun 24.
    View PubMed
  32. Vucicevic D, Blair JE, Binnicker MJ, McCullough AE, Kusne S, Vikram HR, Parish JM, Wengenack NL. The utility of Coccidioides polymerase chain reaction testing in the clinical setting. Mycopathologia. 2010 Nov; 170(5):345-51. Epub 2010 Jun 10.
    View PubMed
  33. Boyce RD, Deziel PJ, Otley CC, Wilhelm MP, Eid AJ, Wengenack NL, Razonable RR. Phaeohyphomycosis due to Alternaria species in transplant recipients. Transpl Infect Dis. 2010 Jun; 12(3):242-50. Epub 2009 Dec 09.
    View PubMed
  34. Babady NE, Hall L, Abbenyi AT, Eisberner JJ, Brown-Elliott BA, Pratt CJ, McGlasson MC, Beierle KD, Wohlfiel SL, Deml SM, Wallace RJ Jr, Wengenack NL. Evaluation of Mycobacterium avium complex clarithromycin susceptibility testing using SLOMYCO Sensititre panels and JustOne strips. J Clin Microbiol. 2010 May; 48(5):1749-52. Epub 2010 Mar 24.
    View PubMed
  35. Sia IG, Orillaza RB, St Sauver JL, Quelapio ID, Lahr BD, Alcaneses RS, Wilson WR, Cockerill FR, Balane GI, Mangubat NV, Wengenack NL, Tupasi TE. Tuberculosis attributed to household contacts in the Philippines. Int J Tuberc Lung Dis. 2010 Jan; 14(1):122-5.
    View PubMed
  36. Forgacs P, Zimmerman SK, Silverman ML, Wengenack NL, Hall L, Roberts GD. Authors' reply. Antimicrob Agents Chemother. 2010; 54(6):2748-9.
    View PubMed
  37. Forgacs P, Wengenack NL, Hall L, Zimmerman SK, Silverman ML, Roberts GD. Tuberculosis and trimethoprim-sulfamethoxazole. Antimicrob Agents Chemother. 2009 Nov; 53(11):4789-93. Epub 2009 Jun 29.
    View PubMed
  38. Klein KR, Hall L, Deml SM, Rysavy JM, Wohlfiel SL, Wengenack NL. Identification of Cryptococcus gattii by use of L-canavanine glycine bromothymol blue medium and DNA sequencing. J Clin Microbiol. 2009 Nov; 47(11):3669-72. Epub 2009 Sep 30.
    View PubMed
  39. Wengenack NL, Binnicker MJ. Fungal molecular diagnostics. Clin Chest Med. 2009 Jun; 30(2):391-408, viii.
    View PubMed
  40. Babady NE, Bestrom JE, Jespersen DJ, Jones MF, Beito EM, Binnicker MJ, Wengenack NL. Evaluation of three commercial latex agglutination kits and a commercial enzyme immunoassay for the detection of cryptococcal antigen. Med Mycol. 2009 May; 47(3):336-8. Epub 2009 Feb 04.
    View PubMed
  41. Hata DJ, Buckwalter SP, Pritt BS, Roberts GD, Wengenack NL. Real-time PCR method for detection of zygomycetes. J Clin Microbiol. 2008 Jul; 46(7):2353-8. Epub 2008 May 14.
    View PubMed
  42. Hall L, Otter JA, Chewins J, Wengenack NL. Deactivation of the dimorphic fungi Histoplasma capsulatum, Blastomyces dermatitidis and Coccidioides immitis using hydrogen peroxide vapor. Med Mycol. 2008 Mar; 46(2):189-91.
    View PubMed
  43. Eid AJ, Berbari EF, Sia IG, Wengenack NL, Osmon DR, Razonable RR. Prosthetic joint infection due to rapidly growing mycobacteria: report of 8 cases and review of the literature. Clin Infect Dis. 2007 Sep 15; 45(6):687-94. Epub 2007 Aug 13.
    View PubMed
  44. Assi MA, Berg JC, Marshall WF, Wengenack NL, Patel R. Mycobacterium gordonae pulmonary disease associated with a continuous positive airway pressure device. Transpl Infect Dis. 2007 Sep; 9(3):249-52. Epub 2007 Jul 01.
    View PubMed
  45. Hata DJ, Hall L, Fothergill AW, Larone DH, Wengenack NL. Multicenter evaluation of the new VITEK 2 advanced colorimetric yeast identification card. J Clin Microbiol. 2007 Apr; 45(4):1087-92. Epub 2007 Jan 31.
    View PubMed
  46. Hall L, Otter JA, Chewins J, Wengenack NL. Use of hydrogen peroxide vapor for deactivation of Mycobacterium tuberculosis in a biological safety cabinet and a room. J Clin Microbiol. 2007 Mar; 45(3):810-5. Epub 2006 Dec 13.
    View PubMed
  47. Binnicker MJ, Buckwalter SP, Eisberner JJ, Stewart RA, McCullough AE, Wohlfiel SL, Wengenack NL. Detection of Coccidioides species in clinical specimens by real-time PCR. J Clin Microbiol. 2007 Jan; 45(1):173-8. Epub 2006 Nov 15.
    View PubMed
  48. Blair JE, Coakley B, Santelli AC, Hentz JG, Wengenack NL. Serologic testing for symptomatic coccidioidomycosis in immunocompetent and immunosuppressed hosts. Mycopathologia. 2006 Nov; 162(5):317-24.
    View PubMed
  49. Uslan DZ, Kowalski TJ, Wengenack NL, Virk A, Wilson JW. Skin and soft tissue infections due to rapidly growing mycobacteria: comparison of clinical features, treatment, and susceptibility. Arch Dermatol. 2006 Oct; 142(10):1287-92.
    View PubMed
  50. Assi MA, Binnicker MJ, Wengenack NL, Deziel PJ, Badley AD. Disseminated coccidioidomycosis in a liver transplant recipient with negative serology: use of polymerase chain reaction. Liver Transpl. 2006 Aug; 12(8):1290-2.
    View PubMed
  51. Pietila MP, Vohra PK, Sanyal B, Wengenack NL, Raghavakaimal S, Thomas CF Jr. Cloning and characterization of CYP51 from Mycobacterium avium. Am J Respir Cell Mol Biol. 2006 Aug; 35(2):236-42. Epub 2006 Mar 16.
    View PubMed
  52. Edson RS, Terrell CL, Brutinel WM, Wengenack NL. Mycobacterium intermedium granulomatous dermatitis from hot tub exposure. Emerg Infect Dis. 2006 May; 12(5):821-3.
    View PubMed
  53. Arcenas RC, Uhl JR, Buckwalter SP, Limper AH, Crino D, Roberts GD, Wengenack NL. A real-time polymerase chain reaction assay for detection of Pneumocystis from bronchoalveolar lavage fluid. Diagn Microbiol Infect Dis. 2006 Mar; 54(3):169-75. Epub 2006 Jan 19.
    View PubMed
  54. Espy MJ, Uhl JR, Sloan LM, Buckwalter SP, Jones MF, Vetter EA, Yao JD, Wengenack NL, Rosenblatt JE, Cockerill FR 3rd, Smith TF. Real-time PCR in clinical microbiology: applications for routine laboratory testing. Clin Microbiol Rev. 2006 Jan; 19(1):165-256.
    View PubMed
  55. Wengenack NL, Lane BD, Hill PJ, Uhl JR, Lukat-Rodgers GS, Hall L, Roberts GD, Cockerill FR 3rd, Brennan PJ, Rodgers KR, Belisle JT, Rusnak F. Purification and characterization of Mycobacterium tuberculosis KatG, KatG(S315T), and Mycobacterium bovis KatG(R463L). Protein Expr Purif. 2004 Aug; 36(2):232-43.
    View PubMed
  56. Wolk DM, Schneider SK, Wengenack NL, Sloan LM, Rosenblatt JE. Real-time PCR method for detection of Encephalitozoon intestinalis from stool specimens. J Clin Microbiol. 2002 Nov; 40(11):3922-8.
    View PubMed
  57. Bulatovic VM, Wengenack NL, Uhl JR, Hall L, Roberts GD, Cockerill FR 3rd, Rusnak F. Oxidative stress increases susceptibility of Mycobacterium tuberculosis to isoniazid. Antimicrob Agents Chemother. 2002 Sep; 46(9):2765-71.
    View PubMed
  58. Wengenack NL, Pierce T, Roberts GD. Identification of Rhizopus zygospores from a skin graft. Journal of Medical Mycology. 2002; 12:136-7.
  59. Rodgers KR, Tang L, Lukat-Rodgers GS, Wengenack NL. Insights into the signal transduction mechanism of RmFixL provided by carbon monoxide recombination kinetics. Biochemistry. 2001 Oct 30; 40(43):12932-42.
    View PubMed
  60. Wengenack NL, Rusnak F. Evidence for isoniazid-dependent free radical generation catalyzed by Mycobacterium tuberculosis KatG and the isoniazid-resistant mutant KatG(S315T). Biochemistry. 2001 Jul 31; 40(30):8990-6.
    View PubMed
  61. Lukat-Rodgers GS, Wengenack NL, Rusnak F, Rodgers KR. Carbon monoxide adducts of KatG and KatG(S315T) as probes of the heme site and isoniazid binding. Biochemistry. 2001 Jun 19; 40(24):7149-57.
    View PubMed
  62. Wengenack NL, Lopes H, Kennedy MJ, Tavares P, Pereira AS, Moura I, Moura JJ, Rusnak F. Redox potential measurements of the Mycobacterium tuberculosis heme protein KatG and the isoniazid-resistant enzyme KatG(S315T): insights into isoniazid activation. Biochemistry. 2000 Sep 19; 39(37):11508-13.
    View PubMed
  63. Lukat-Rodgers GS, Wengenack NL, Rusnak F, Rodgers KR. Spectroscopic comparison of the heme active sites in WT KatG and its S315T mutant. Biochemistry. 2000 Aug 15; 39(32):9984-93.
    View PubMed
  64. Wengenack NL, Hoard HM, Rusnak F. Isoniazid oxidation by Mycobacterium tuberculosis KatG: a role for superoxide which correlates with isoniazid susceptibility. J Am Chem Soc. 1999 Oct 20; 121(41):9748-9749.
  65. Wengenack NL, Jensen MP, Rusnak F, Stern MK. Mycobacterium tuberculosis KatG is a peroxynitritase. Biochem Biophys Res Commun. 1999 Mar 24; 256(3):485-7.
    View PubMed
  66. Wengenack NL, Todorovic S, Yu L, Rusnak F. Evidence for differential binding of isoniazid by Mycobacterium tuberculosis KatG and the isoniazid-resistant mutant KatG(S315T). Biochemistry. 1998 Nov 10; 37(45):15825-34.
    View PubMed
  67. Wengenack NL, Uhl JR, St Amand AL, Tomlinson AJ, Benson LM, Naylor S, Kline BC, Cockerill FR 3rd, Rusnak F. Recombinant Mycobacterium tuberculosis KatG(S315T) is a competent catalase-peroxidase with reduced activity toward isoniazid. J Infect Dis. 1997 Sep; 176(3):722-7.
    View PubMed