Publications

  1. Mazzone A, Bernard CE, Strege PR, Beyder A, Galietta LJ, Pasricha PJ, Rae JL, Parkman HP, Linden DR, Szurszewski JH, Ordog T, Gibbons SJ, Farrugia G. Altered expression of Ano1 variants in human diabetic gastroparesis. J Biol Chem. 2011 Apr 15; 286(15):13393-403. Epub 2011 Feb 24.
    View PubMed
  2. Beyder A, Rae JL, Bernard C, Strege PR, Sachs F, Farrugia G. Mechanosensitivity of Nav1.5, a voltage-sensitive sodium channel. J Physiol. 2010 Dec 15; 588(Pt 24):4969-85. Epub 2010 Nov 1
    View PubMed
  3. Saito YA, Strege PR, Tester DJ, Locke GR 3rd, Talley NJ, Bernard CE, Rae JL, Makielski JC, Ackerman MJ, Farrugia G. Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy. Am J Physiol Gastrointest Liver Physiol. 2009 Feb; 296(2):G211-8. Epub 2008 Dec 04.
    View PubMed
  4. Goetz MP, Suman VJ, Couch FJ, Ames MM, Rae JM, Erlander MG, Ma XJ, Sgroi DC, Reynolds CA, Lingle WL, Weinshilboum RM, Flockhart DA, Desta Z, Perez EA, Ingle JN. Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance. Clin Cancer Res. 2008 Sep 15; 14(18):5864-8.
    View PubMed
  5. Rae JL, Levis RA. Fabrication of patch pipets. Current Protocols in Neuroscience. 2004 May; Chapter 6(Suppl 26):Unit 6.3.
    View PubMed
  6. Mathias RT, Rae JL. The lens: local transport and global transparency. Exp Eye Res. 2004 Mar; 78(3):689-98.
    View PubMed
  7. Ou Y, Gibbons SJ, Miller SM, Strege PR, Rich A, Distad MA, Ackerman MJ, Rae JL, Szurszewski JH, Farrugia G. SCN5A is expressed in human jejunal circular smooth muscle cells. Neurogastroenterol Motil. 2002 Oct; 14(5):477-86.
    View PubMed
  8. Lyford GL, Strege PR, Shepard A, Ou YJ, Ermilov L, Miller SM, Gibbons SJ, Rae JL, Szurszewski JH, Farrugia G. alpha(1C) (Ca(v)1.2) L-type calcium channel mediates mechanosensitive calcium regulation. Am J Physiol Cell Physiol. 2002 Sep; 283(3):C1001-8.
    View PubMed
  9. Rae JL, Levis RA. Single-cell electroporation. Pflugers Arch. 2002 Feb; 443(4):664-70.
    View PubMed
  10. Holm AN, Rich A, Miller SM, Strege P, Ou Y, Gibbons S, Sarr MG, Szurszewski JH, Rae JL, Farrugia G. Sodium current in human jejunal circular smooth muscle cells. Gastroenterology. 2002 Jan; 122(1):178-87.
    View PubMed
  11. Rae JL. Electroporation of single cells. Axobits. 2002; 34:7-11.
  12. Rae JL, Shepard AR. Kv3.3 potassium channels in lens epithelium and corneal endothelium. Exp Eye Res. 2000 Mar; 70(3):339-48.
    View PubMed
  13. Rae JL, Shepard AR. Kir2.1 Potassium channels and corneal epithelia. Curr Eye Res. 2000 Feb; 20(2):144-52.
    View PubMed
  14. Rae JL, Levis RL. An electrode coating elastomer to replace sylgard 184. Axobits. 2000; 29:6-7.
  15. Farrugia G, Holm AN, Rich A, Sarr MG, Szurszewski JH, Rae JL. A mechanosensitive calcium channel in human intestinal smooth muscle cells. Gastroenterology. 1999 Oct; 117(4):900-5.
    View PubMed
  16. Shepard AR, Rae JL. Electrically silent potassium channel subunits from human lens epithelium. Am J Physiol. 1999 Sep; 277(3 Pt 1):C412-24.
    View PubMed
  17. Shepard AR, Rae JL. "Microprep" method for rapidly isolating plasmid DNAs for restriction enzyme analysis. Biotechniques. 1999 May; 26(5):868-70.
    View PubMed
  18. Rich A, Farrugia G, Rae JL. Effects of melatonin on ionic currents in cultured ocular tissues. Am J Physiol. 1999 Apr; 276(4 Pt 1):C923-9.
    View PubMed
  19. Shepard AR, Rae JL. Ion transporters and receptors in cDNA libraries from lens and cornea epithelia. Curr Eye Res. 1998 Jul; 17(7):708-19.
    View PubMed
  20. Rae JL, Shepard AR. Molecular biology electrophysiology of calcium-activated potassium channels from lens epithelium. Curr Eye Res. 1998 Mar; 17(3):264-275.
    View PubMed
  21. Rae JL, Shepard AR. Inwardly rectifying potassium channels in lens epithelium are from the IRK1 (Kir 2.1) family. Exp Eye Res. 1998 Mar; 66(3):347-59.
    View PubMed
  22. Farrugia G, Miller SM, Rich A, Liu X, Maines MD, Rae JL, Szurszewski JH. Distribution of heme oxygenase and effects of exogenous carbon monoxide in canine jejunum. Am J Physiol. 1998 Feb; 274(2 Pt 1):G350-8.
    View PubMed
  23. Rae JL, Shepard AR. Identification of potassium channels in human lens epithelium. Current Topics in Membranes. 1998; 45:69-104.
  24. Levis Ra, Rae JL. Low noise patch clamp techniques. Methods in Enzumology. 1998; 293:218-66.
  25. Shepard AR, Rae JL. Magnetic bead capture of cDNAs from double-stranded plasmid cDNA libraries. Nucleic Acids Res. 1997 Aug 1; 25(15):3183-5.
    View PubMed
  26. Rich A, Bartling C, Farrugia G, Rae JL. Effects of pH on the potassium current in rabbit corneal epithelial cells. Am J Physiol. 1997 Feb; 272(2 Pt 1):C744-53.
    View PubMed
  27. Mathias RT, Rae JL, Baldo GJ. Physiological properties of the normal lens. Physiol Rev. 1997 Jan; 77(1):21-50.
    View PubMed
  28. Rae JL, Shepard AR. Chapter 4 identification of potassium channels in human lens epithelium. Curr Top Membr Transp. 1997; 45(C):69-104.
  29. Rae JL, Watsky MA. Ionic channels in corneal endothelium. Am J Physiol Cell Physiol. 1996 Apr; 39(4):C 975-C 989.
  30. Rae JL, Bartling C, Rae J, Mathias RT. Dye transfer between cells of the lens. J Membr Biol. 1996 Mar; 150(1):89-103.
    View PubMed
  31. Rae JL, Watsky M. Ion channels in corneal endothelium. Am J Physiol. 1996; 270:C975-89.
    View PubMed
  32. Farrugia G, Rich A, Rae JL, Sarr MG, Szurszewski JH. Calcium currents in human and canine jejunal circular smooth muscle cells. Gastroenterology. 1995 Sep; 109(3):707-17.
    View PubMed
  33. Rae JL, Rich A, Zamudio AC, Candia OA. Effect of Prozac on whole cell ionic currents in lens and corneal epithelia. Am J Physiol. 1995 Jul; 269(1 Pt 1):C250-6.
    View PubMed
  34. Dewey J, Bartling C, Rae JL. A non-enzymatic method for lens decapsulation which leaves the epithelial cells attached to the fibers. Curr Eye Res. 1995 May; 14(5):357-62.
    View PubMed
  35. Rich A, Rae JL. Calcium entry in rabbit corneal epithelial cells: evidence for a nonvoltage dependent pathway. J Membr Biol. 1995 Mar; 144(2):177-84.
    View PubMed
  36. Rae JL. Outwardly rectifying potassium currents in lens epithelial cell membranes. Curr Eye Res. 1994 Sep; 13(9):679-86.
    View PubMed
  37. Rich A, Farrugia G, Rae JL. Carbon monoxide stimulates a potassium-selective current in rabbit corneal epithelial cells. Am J Physiol. 1994 Aug; 267(2 Pt 1):C435-42.
    View PubMed
  38. Farrugia G, Rae JL, Sarr MG, Szurszewski JH. Potassium current in circular smooth muscle of human jejunum activated by fenamates. Am J Physiol. 1993 Nov; 265(5 Pt 1):G873-9.
    View PubMed
  39. Levis RA, Rae JL. The use of quartz patch pipettes for low noise single channel recording. Biophys J. 1993 Oct; 65(4):1666-77.
    View PubMed
  40. Farrugia G, Rae JL, Szurszewski JH. Characterization of an outward potassium current in canine jejunal circular smooth muscle and its activation by fenamates. J Physiol. 1993 Aug; 468:297-310.
    View PubMed
  41. Rae JL. Ion channels in ocular epithelia. Invest Ophthalmol Vis Sci. 1993 Aug; 34(9):2608-12.
    View PubMed
  42. Watsky MA, Rae JL. Ion channel involvement in the temperature-sensitive response of the rabbit corneal endothelial cell resting membrane potential. J Membr Biol. 1993 Jul; 135(1):61-71.
    View PubMed
  43. Farrugia G, Irons WA, Rae JL, Sarr MG, Szurszewski JH. Activation of whole cell currents in isolated human jejunal circular smooth muscle cells by carbon monoxide. Am J Physiol. 1993 Jun; 264(6 Pt 1):G1184-9.
    View PubMed
  44. Farrugia G, Rae J. Effect of volume changes on a potassium current in rabbit corneal epithelial cells. Am J Physiol. 1993 May; 264(5 Pt 1):C1238-45.
    View PubMed
  45. O'Grady SM, Cooper KE, Rae JL. Regulation of a voltage-dependent, calcium-activated K conductance by cyclic GMP in dissociated flounder enterocytes. Journal of Comparative Physiology - B, Biochemical, Systemic, & Environmental Physiology. 1993; 163(7):581-6.
  46. Cooper K, Watsky M, Rae JL. Potassium currents from isolated frog lens epithelia cells. Exp Eye Res. 1992 Dec; 55:861-868.
    View PubMed
  47. Rae JL, Mathias RT, Cooper K, Baldo G. Divalent cation effects on lens conductance and stretch-activated cation channels. Exp Eye Res. 1992 Jul; 55(1):135-44.
    View PubMed
  48. Farrugia G, Rae JL. Regulation of a potassium-selective current in rabbit corneal epithelium by cyclic GMP, carbachol and diltiazem. J Membr Biol. 1992 Jul; 129(1):99-107.
    View PubMed
  49. Rae JL, Farrugia G. Whole-cell potassium current in rabbit corneal epithelium activated by fenamates. J Membr Biol. 1992 Jul; 129(1):81-97.
    View PubMed
  50. Watsky MA, Rae JL. Dye coupling in the corneal endothelium: effects of ouabain and extracellular calcium removal. Cell Tissue Res. 1992 Jul; 269(1):57-63.
    View PubMed
  51. Rae JL, Rae JS. Whole-cell currents from noncultured human lens epithelium. Invest Ophthalmol Vis Sci. 1992 Jun; 33(7):2262-8.
    View PubMed
  52. Watsky MA, Cooper K, Rae JL. Transient outwardly rectifying potassium channel in the rabbit corneal endothelium. J Membr Biol. 1992 Jun; 128(2):123-32.
    View PubMed
  53. Rae JL, Dewey J, Rae JS. The large-conductance potassium ion channel of rabbit corneal epithelium is blocked by quinidine. Invest Ophthalmol Vis Sci. 1992 Feb; 33(2):286-90.
    View PubMed
  54. Watsky MA, Rae JL. Initial characterization of whole-cell currents from freshly dissociated corneal keratocytes. Curr Eye Res. 1992 Feb; 11(2):127-34.
    View PubMed
  55. Rae JL, Levis RA. A method for exceptionally low noise single channel recordings. Pflugers Arch. 1992; 420:618-20.
    View PubMed
  56. Rae JL, Levis RA. A technique for ultra low noise single-channel recording using an Axopatch 200A, quartz pipettes, and silicone fluid. Axobits. 1992; 11:9-12.
  57. Levis RA, Rae JL. Construction a patch clamp setup. Methods Enzymol. 1992; 207:14-66.
    View PubMed
  58. Rae JL, Levis RA. Glass technology for patch clamp electrodes. Methods Enzymol. 1992; 207:66-92.
    View PubMed
  59. Mathias RT, Riquelme G, Rae JL. Cell to cell communication and pH in the frog lens. J Gen Physiol. 1991 Dec; 98(6):1085-103.
    View PubMed
  60. Cooper K, Rae JL, Dewey J. Inwardly rectifying potassium current in mammalian lens epithelial cells. Am J Physiol. 1991 Jul; 261(1 Pt 1):C115-23.
    View PubMed
  61. Rae J, Cooper K, Gates P, Watsky M. Low access resistance perforated patch recordings using amphotericin B. J Neurosci Methods. 1991 Mar; 37(1):15-26.
    View PubMed
  62. Watsky MA, Rae JL. Resting voltage measurements of the rabbit corneal endothelium using patch-current clamp techniques. Invest Ophthalmol Vis Sci. 1991 Jan; 32(1):106-11.
    View PubMed
  63. O'Grady SM, Cooper KE, Rae JL. Cyclic GMP regulation of a voltage-activated K channel in dissociated enterocytes. Am J Physiol. 1991; 124:159-67.
  64. Rae JL. Physiology of the lens 1-14 in:. Duane's Clinical Ophthalmology Tasman W Haeger EA, Editors JB Lippincott Company, 1991.
  65. Rae JL, Fernandez J. Perforated patch recordings in physiology. NIPS. 1991; 6:273-7.
  66. Rae JL. Perforated-patch recording techniques. Axobits. 1991; 8:6-10.
  67. Rae JL, Dewey J, Rae JS, Cooper K. A maxi calcium-activated potassium channel from chick lens epithelium. Curr Eye Res. 1990 Sep; 9(9):847-61.
    View PubMed
  68. Cooper K, Gates P, Rae JL, Dewey J. Electrophysiology of cultured human lens epithelial cells. J Membr Biol. 1990 Sep; 117(3):285-98.
    View PubMed
  69. Rae JL, Dewey J, Rae JS, Nesler M, Cooper K. Single potassium channels in corneal epithelium. Invest Ophthalmol Vis Sci. 1990 Sep; 31(9):1799-809.
    View PubMed
  70. Rae JL, Dewey J, Cooper K, Gates P. A non-selective cation channel in rabbit corneal endothelium activated by internal calcium and inhibited by internal ATP. Exp Eye Res. 1990 Apr; 50(4):373-84.
    View PubMed
  71. Rae JL, Cooper K. New techniques for the study of lens electrophysiology. Exp Eye Res. 1990; 50:603-14.
    View PubMed
  72. Rae JL, Dewey J, Cooper K, Gates P. Potassium channel in rabbit corneal endothelium activated by external anions. J Membr Biol 1990; 114:29-36. J Membr Biol. 1990; 114:29-36.
    View PubMed
  73. Rae JL, Dewey J, Cooper K. Properties of single potassium-selective ionic channels from the apical membrane of rabbit corneal endothelium. Exp Eye Res. 1989; 49:591-609.
    View PubMed
  74. Rae JL, Lewno AW, Cooper K, Gates P. Dye and electrical coupling between cells of the rabbit corneal endothelium. Curr Eye Res. 1989; 8:859-69.
    View PubMed
  75. Gates P, Cooper K, Rae JL, Eisenberg RS. Predictions of diffusion models for one-ion membrane channels. Prog Biophys Molec Biol. 1989; 53:153-96.
  76. Rae JL, Cooper KE. Potassium channels in chick lens epithelium change with maturation. Lens Eye Toxic Res. 1989; 6(4):833-43.
    View PubMed
  77. Cooper K, Rae JL, Gates P. Membrane and junctional properties of dissociaed frog lens epithelial cells. J Membr Biol. 1989; 11:215-27.
  78. Rae JL. Pharmacologic blockade of ionic channels in lens membranes. Ophthalmic Res. 1988; 20(3):132-8.
    View PubMed
  79. Cooper KE, Tang JM, Rae JL, Eisenberg RS. A cation channel in frog lens epithelia responsive to pressue and calcium. J Memb Biol. 1986; 93:259-69.
  80. Rae JL. Potassium channels from chick lens epithelium. Federation Proc. 1986; 45:2718-22.
  81. Kuszak JR, Macsai MS, Bloom KJ, Rae JL, Weinstein RS. Cell-to-cell fusions of lens fiber cells in situ: correlative light, scanning electron microscopy and freeze-fracture studies. J Ultrastrct Res. 1985; 93:144-60.
  82. Kuszak JR, Shek YH, Carney KC, Rae JL. A correlative freeze-etch and electrophysiological study of communicating functions in crystalline lenses. Cur Eye Res. 1985; 4:1145-53.
  83. Mathias RT, Rae JL. Steady state voltages in the frog lens. Cur Eye Res. 1985; 4:421-30.
  84. Mathias RT, Rae JL. Transport properties of the lens. Am J Physiol 249 1985.
  85. Mathias RT, Rae JL. Transport properties of the lens. Cell Physiol. 1985; 18:C181-90.
  86. Mathias Rt, Rae JL, Ebihara L, McCarthy RT. The localization of transport properties in the frog lens. Biophys J. 1985; 48:423-34.
    View PubMed
  87. Rae JL. The application of patch clamp methods to ocular epithelia. Cur Eye Res. 1985; 4:409-20.
  88. Kuszak JR, Bertram BA, Macsai MS, Rae JL. Sutures of the crystalline lens: a review. Scanning Electron Microscopy. 1984; 3:1369-78.
  89. Rae JL. The patch voltage clamp: its application to lens research. Lens Research. 1984; 2:61-87.
  90. Rae JL, Levis Ra. Patch clamp recordings from the epithelium of the lens obtained using glass selected for low noise and improved sealing proerties. Biophys J. 1984; 45:144-6.
  91. Rae JL, Levis RA. Patch voltage clamp of lens epithelial cells: theory and practice. Molec Physiol. 1984; 6:115-62.
  92. Rae JL, Truitt K, Kuszak J. The use of procion dyes for light microscopy of the frog lens. Invest Ophthal and Vis Sci. 1983; 24:1167-71.
  93. Kuszak J, Macsai MS, Rae JL. Sero scanning electron microscopy of the crystalline lens. Scanning Electron Microscopy. 1983; 3:1415-25.
  94. Rae JL, Kuszak JR. The electrical coupling of epithelium and fibers in the frog lens. Exp Eye Res. 1983; 36:317-26.
    View PubMed
  95. Rae JL, Thompson RD, Eisenberg RS. The effect of 2-4 dinitrophenol on cell to cell communication in the frog lens. Exp Eye Res. 1982; 35:597-609.
    View PubMed
  96. Rae JL, Truitt KD, Kuszak JR. A simple fluorescence technique for light microscopy of the crystalline lens. Curr Eye Res. 1982; 2:1-5.
    View PubMed
  97. Kuszak J, Rae JL. Scanning electron microscopy of the frog lens. Exp Eye Res. 1982; 35:499-519.
    View PubMed
  98. Kuszak JR, Rae JL, Pauli BU, Weinstein RS. Rotary replication of lens gap junctions. J Ultrastrc Res. 1982; 81:249-56.
  99. Rae JL, Mathias RT, Eisenberg RS. Physiological role of the membranes and extracellular space within the ocular lens. Exp Eye Res. 1982; 35:471-89.
    View PubMed
  100. Mathias RT, Rae JL, Eisenberg RS. The lens as a nonuniform spherical syncytium. Biophys J. 1981; 34:61-83.
    View PubMed
  101. Koblasz A, Rae JL, Correia MJ, NI MD. Weinder Kernels and Frequency Response Functions for the Human Retina. IEEE - Biomedical. 1980. Vol BME 27:68-75.
  102. Rae JL, Stacey T. Lanthanum and procion yellow as extracellular markers in the crystalline lens of the rat. Exp Eye Res. 1979; 28:1-21.
    View PubMed
  103. Mathias RT, Rae JL, Eisenberg RS. Electrical properties of structural components of the crystalline lens 1979. Biophys J. 1979; 181-21.
  104. Eisenberg RS, Mathias RT, Rae JL. Measurement, modeling, and analysis of the linear electric properties of cells. Ann New York Acad Science. 1977; 303:342-54.
  105. Rae JL, Riddle WR, Law WC, Welford NT. A biphasic 60-Hz synchronizer circuit for the recording of visually evoked responses in high-noise environments. Behavior Research Methods and Instrumentation. 1977; 9:341-4.
  106. Ni MD, Correia MJ, Rae JL, Koblasz AJ. A realtime mini-computer program for calculation of frequency responses function and conherence funtion using digital fourier methods. Proceedings of Mima Montreal International Show and Symposia and Mini and Micro Computers, Montreal, Canada. 1977.
  107. Eisenberg RS, Rae JL. Current-voltage relationships in the crystalline lens. J Physiol. 1976; 262:285-300.
    View PubMed
  108. Rae JL, Stacey T. Intracellular markers in the crystalline lens of the rat. Documenta Ophthalomologica Proceedings Series Progress of Lens Biochemistry Research 233-9 1976.
  109. Rae JL. The movement of procion dye in the crystalline lens. Invest Ophthal. 1974; 13:147-50.
    View PubMed
  110. Rae JL, Germer HA. Junction potentials in the crystalline lens. L Appl Physiol. 1974; 37:464-67.
  111. Neville MC, Paterson CA, Rae JL, Woessner DE. Nuclear magnetic resonance studies and water 'ordering' in the crystalline lens. Science. 1974; 184:1072-74.
    View PubMed
  112. Paterson CA, Rae JL. The potential difference of the rabbit lens. Exp Eye Res. 1974; 15:507-8.
  113. Rae JL. Potential Profiles in the crystalline lens. Exp Eye Res. 1974; 19:227-34.
    View PubMed
  114. Rae JL. Voltage compartments in the lens. Exp Eye Res. 1974; 19:235-42.
    View PubMed
  115. Rae JL, Blankenship JE. Bioelectric measurements in the frog lens. Exp Eye Res. 1973; 15:269-77.
  116. Rae JL. The potential difference of the frog lens. Exp Eye Res. 1973; 15:485-94.
    View PubMed
  117. Rae JL, Hoffert JR, Fromm PO. Studies on the normal lens potentila of the rainbow trout (Salmo gairdneri). Exp Eye Res. 1970; 10:93-101.
    View PubMed