Publications

  1. Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Gunter JL, Schwarz CG, Reid RI, Spychalla AJ, Lowe VJ, Jack CR Jr, Whitwell JL. The evolution of primary progressive apraxia of speech. Brain. 2014 Oct; 137(Pt 10):2783-95. Epub 2014 Aug 11.
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  2. Carrasquillo MM, Crook JE, Pedraza O, Thomas CS, Pankratz VS, Allen M, Nguyen T, Malphrus KG, Ma L, Bisceglio GD, Roberts RO, Lucas JA, Smith GE, Ivnik RJ, Machulda MM, Graff-Radford NR, Petersen RC, Younkin SG, Ertekin-Taner N. Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease. Neurobiol Aging. 2014 Aug 04.
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  3. Vemuri P, Lesnick TG, Przybelski SA, Machulda M, Knopman DS, Mielke MM, Roberts RO, Geda YE, Rocca WA, Petersen RC, Jack CR Jr. Association of lifetime intellectual enrichment with cognitive decline in the older population. JAMA Neurol. 2014 Aug 1; 71(8):1017-24.
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  4. Jung Y, Whitwell JL, Duffy JR, Strand EA, Machulda MM, Senjem ML, Lowe V, Jack CR Jr, Josephs KA. Amyloid burden correlates with cognitive decline in Alzheimer's disease presenting with aphasia. Eur J Neurol. 2014 Jul; 21(7):1040-3. Epub 2013 Dec 16.
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  5. Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Lowe VJ, Jack CR Jr, Whitwell JL. APOE epsilon4 influences beta-amyloid deposition in primary progressive aphasia and speech apraxia. Alzheimers Dement. 2014 Jun 28.
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  6. Botha H, Duffy JR, Strand EA, Machulda MM, Whitwell JL, Josephs KA. Nonverbal oral apraxia in primary progressive aphasia and apraxia of speech. Neurology. 2014 May 13; 82(19):1729-35. Epub 2014 Apr 11.
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  7. Wicklund MR, Duffy JR, Strand EA, Machulda MM, Whitwell JL, Josephs KA. Quantitative application of the primary progressive aphasia consensus criteria. Neurology. 2014 Apr 1; 82(13):1119-26. Epub 2014 Mar 05.
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  8. Josephs KA, Duffy JR, Strand EA, Machulda MM, Vemuri P, Senjem ML, Perkerson RB, Baker MC, Lowe V, Jack CR Jr, Rademakers R, Whitwell JL. Progranulin-associated PiB-negative logopenic primary progressive aphasia. J Neurol. 2014 Mar; 261(3):604-14. Epub 2014 Jan 22.
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  9. Mielke MM, Savica R, Wiste HJ, Weigand SD, Vemuri P, Knopman DS, Lowe VJ, Roberts RO, Machulda MM, Geda YE, Petersen RC, Jack CR Jr. Head trauma and in vivo measures of amyloid and neurodegeneration in a population-based study. Neurology. 2014 Jan 7; 82(1):70-6. Epub 2013 Dec 26.
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  10. Whitwell JL, Jack CR Jr, Duffy JR, Strand EA, Gunter JL, Senjem ML, Murphy MC, Kantarci K, Machulda MM, Lowe VJ, Josephs KA. Microbleeds in the logopenic variant of primary progressive aphasia. Alzheimers Dement. 2014 Jan; 10(1):62-6. Epub 2013 Apr 3
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  11. Whitwell JL, Lowe VJ, Duffy JR, Strand EA, Machulda MM, Kantarci K, Wille SM, Senjem ML, Murphy MC, Gunter JL, Jack CR Jr, Josephs KA. Elevated occipital beta-amyloid deposition is associated with widespread cognitive impairment in logopenic progressive aphasia. J Neurol Neurosurg Psychiatry. 2013 Dec; 84(12):1357-64. Epub 2013 Aug 14.
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  12. Machulda MM, Whitwell JL, Duffy JR, Strand EA, Dean PM, Senjem ML, Jack CR Jr, Josephs KA. Identification of an atypical variant of logopenic progressive aphasia. Brain Lang. 2013 Nov; 127(2):139-44. Epub 2013 Apr 06.
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  13. Adeli A, Drubach DA, Machulda MM. Resolution of neuropsychological and FDG-PET abnormalities in a patient with neuropsychiatric systemic lupus erythematosus. Cogn Behav Neurol. 2013 Sep; 26(3):161-6.
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  14. Wicklund MR, Duffy JR, Strand EA, Whitwell JL, Machulda MM, Josephs KA. Aphasia with left occipitotemporal hypometabolism: a novel presentation of posterior cortical atrophy? J Clin Neurosci. 2013 Sep; 20(9):1237-40. Epub 2013 Jul 11.
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  15. Josephs KA, Papenfuss SM, Duffy JR, Strand EA, Machulda MM, Whitwell JL, Petersen RC. Occupational differences between Alzheimer's and aphasic dementias: implication for teachers. Am J Alzheimers Dis Other Demen. 2013 Sep; 28(6):612-6. Epub 2013 Jul 09.
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  16. Mielke MM, Roberts RO, Savica R, Cha R, Drubach DI, Christianson T, Pankratz VS, Geda YE, Machulda MM, Ivnik RJ, Knopman DS, Boeve BF, Rocca WA, Petersen RC. Assessing the temporal relationship between cognition and gait: slow gait predicts cognitive decline in the Mayo Clinic Study of Aging. J Gerontol A Biol Sci Med Sci. 2013 Aug; 68(8):929-37. Epub 2012 Dec 18.
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  17. Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Lowe VJ, Jack CR Jr, Whitwell JL. Syndromes dominated by apraxia of speech show distinct characteristics from agrammatic PPA. Neurology. 2013 Jul 23; 81(4):337-45. Epub 2013 Jun 26.
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  18. Kantarci K, Weigand SD, Przybelski SA, Preboske GM, Pankratz VS, Vemuri P, Senjem ML, Murphy MC, Gunter JL, Machulda MM, Ivnik RJ, Roberts RO, Boeve BF, Rocca WA, Knopman DS, Petersen RC, Jack CR Jr. MRI and MRS predictors of mild cognitive impairment in a population-based sample. Neurology. 2013 Jul 9; 81(2):126-33. Epub 2013 Jun 12.
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  19. Whitwell JL, Duffy JR, Strand EA, Xia R, Mandrekar J, Machulda MM, Senjem ML, Lowe VJ, Jack CR Jr, Josephs KA. Distinct regional anatomic and functional correlates of neurodegenerative apraxia of speech and aphasia: an MRI and FDG-PET study. Brain Lang. 2013 Jun; 125(3):245-52. Epub 2013 Mar 28.
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  20. Whitwell JL, Duffy JR, Strand EA, Machulda MM, Senjem ML, Gunter JL, Kantarci K, Eggers SD, Jack CR Jr, Josephs KA. Neuroimaging comparison of primary progressive apraxia of speech and progressive supranuclear palsy. Eur J Neurol. 2013 Apr; 20(4):629-37. Epub 2012 Oct 18
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  21. Machulda MM, Pankratz VS, Christianson TJ, Ivnik RJ, Mielke MM, Roberts RO, Knopman DS, Boeve BF, Petersen RC. Practice effects and longitudinal cognitive change in normal aging vs. incident mild cognitive impairment and dementia in the Mayo Clinic Study of Aging. Clin Neuropsychol. 2013; 27(8):1247-64. Epub 2013 Sep 17.
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  22. Madhavan A, Whitwell JL, Weigand SD, Duffy JR, Strand EA, Machulda MM, Tosakulwong N, Senjem ML, Gunter JL, Lowe VJ, Petersen RC, Jack CR Jr, Josephs KA. FDG PET and MRI in logopenic primary progressive aphasia versus dementia of the Alzheimer's type. PLoS One. 2013; 8(4):e62471. Epub 2013 Apr 23.
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  23. Welker KM, De Jesus RO, Watson RE, Machulda MM, Jack CR. Altered functional MR imaging language activation in elderly individuals with cerebral leukoaraiosis. Radiology. 2012 Oct; 265(1):222-32. Epub 2012 Aug 13.
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  24. Josephs KA, Duffy JR, Strand EA, Machulda MM, Senjem ML, Master AV, Lowe VJ, Jack CR Jr, Whitwell JL. Characterizing a neurodegenerative syndrome: primary progressive apraxia of speech. Brain. 2012 May; 135(Pt 5):1522-36. Epub 2012 Mar 01.
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  25. Boeve BF, Boylan KB, Graff-Radford NR, DeJesus-Hernandez M, Knopman DS, Pedraza O, Vemuri P, Jones D, Lowe V, Murray ME, Dickson DW, Josephs KA, Rush BK, Machulda MM, Fields JA, Ferman TJ, Baker M, Rutherford NJ, Adamson J, Wszolek ZK, Adeli A, Savica R, Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72. Brain. 2012 Mar; 135(Pt 3):765-83.
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  26. Jones DT, Vemuri P, Murphy MC, Gunter JL, Senjem ML, Machulda MM, Przybelski SA, Gregg BE, Kantarci K, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. Non-stationarity in the "resting brain's" modular architecture. PLoS One. 2012; 7(6):e39731. Epub 2012 Jun 28.
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  27. Jones DT, Machulda MM, Vemuri P, McDade EM, Zeng G, Senjem ML, Gunter JL, Przybelski SA, Avula RT, Knopman DS, Boeve BF, Petersen RC, Jack CR Jr. Age-related changes in the default mode network are more advanced in Alzheimer disease. Neurology. 2011 Oct 18; 77(16):1524-31. Epub 2011 Oct 05.
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  28. Machulda MM, Jones DT, Vemuri P, McDade E, Avula R, Przybelski S, Boeve BF, Knopman DS, Petersen RC, Jack CR Jr. Effect of APOE epsilon4 status on intrinsic network connectivity in cognitively normal elderly subjects. Arch Neurol. 2011 Sep; 68(9):1131-6. Epub 2011 May 09.
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  29. Fields JA, Machulda M, Aakre J, Ivnik RJ, Boeve BF, Knopman DS, Petersen RC, Smith GE. Utility of the DRS for predicting problems in day-to-day functioning. Clin Neuropsychol. 2010 Oct; 24(7):1167-80.
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  30. Machulda MM, Senjem ML, Weigand SD, Smith GE, Ivnik RJ, Boeve BF, Knopman DS, Petersen RC, Jack CR. Functional magnetic resonance imaging changes in amnestic and nonamnestic mild cognitive impairment during encoding and recognition tasks. J Int Neuropsychol Soc. 2009 May; 15(3):372-82.
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  31. Machulda MM, Ivnik RJ, Smith GE, Ferman TJ, Boeve BF, Knopman D, Petersen RC, Tangalos EG. "Mayo's older Americans normative studies: Visual form discrimination and copy trial of the Rey-Osterrieth Complex Figure": Corrigendum. J Clin Exp Neuropsychol. 2008; 30(1):132.
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  32. Smith GE, Pankratz VS, Negash S, Machulda MM, Petersen RC, Boeve BF, Knopman DS, Lucas JA, Ferman TJ, Graff-Radford N, Ivnik RJ. A plateau in pre-Alzheimer memory decline: evidence for compensatory mechanisms? Neurology. 2007 Jul 10; 69(2):133-9.
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  33. Cerhan JH, Ivnik RJ, Smith GE, Machulda MM, Boeve BF, Knopman DS, Petersen RC, Tangalos EG. Alzheimer's disease patients' cognitive status and course years prior to symptom recognition. Aging Neuropsychology & Cognition. 2007 May; 14(3):227-35.
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  34. Machulda MM, Ivnik RJ, Smith GE, Ferman TJ, Boeve BF, Knopman D, Petersen RC, Tangalos EG. Mayo's Older Americans Normative Studies: Visual Form Discrimination and copy trial of the Rey-Osterrieth Complex Figure. J Clin Exp Neuropsychol. 2007 May; 29(4):377-84.
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  35. Machulda MM, Ward HA, Borowski B, Gunter JL, Cha RH, O'Brien PC, Petersen RC, Boeve BF, Knopman D, Tang-Wai DF, Ivnik RJ, Smith GE, Tangalos EG, Jack CR Jr. Comparison of memory fMRI response among normal, MCI, and Alzheimer's patients. Neurology. 2003 Aug 26; 61(4):500-6.
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  36. Machulda MM, Ward HA, Cha R, O'Brien P, Jack CR Jr. Functional inferences vary with the method of analysis in fMRI. Neuroimage. 2001 Nov; 14(5):1122-7.
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  37. Machulda MM, Bergquist TF, Ito V, Chew S. Relationship between stress, coping, and postconcussion symptoms in a healthy adult population. Arch Clin Neuropsychol. 1998 Jul; 13(5):415-24.
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  38. Malec JF, Machulda MM, Moessner AM. Differing problem perceptions of staff, survivors, and significant others after brain injury. J Head Trauma Rehabil. 1997; 12(3):1-13.
  39. Malec JF, Machulda MM, Smigielski JS. Cluster analysis of neuropsychological tests among patients with traumatic brain injury (TBI): implications for a model of TBI-related disability. Clin Neuropsychol. 1993; 1:48-58.
  40. Shen WK, Tung RT, Machulda MM, Kurachi Y. Essential role of nucleotide diphosphates in nicorandil-mediated activation of cardiac ATP-sensitive K+ channel. A comparison with pinacidil and lemakalim. Circ Res. 1991 Oct; 69(4):1152-8.
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