Publications

  1. Hann CR, Vercnocke AJ, Bentley MD, Jorgensen SM, Fautsch MP. Anatomic Changes in Schlemm's Canal and Collector Channels in Normal and Primary Open-Angle Glaucoma Eyes Using Low and High Perfusion Pressures. Invest Ophthalmol Vis Sci. 2014 Sep; 55(9):5834-41. Epub 2014 Aug 19.
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  2. Winkler NS, Fautsch MP. Effects of prostaglandin analogues on aqueous humor outflow pathways. J Ocul Pharmacol Ther. 2014 Mar 1; 30(2-3):102-9.
  3. Winkler NS, Fautsch MP. Effects of Prostaglandin Analogues on Aqueous Humor Outflow Pathways. J Ocul Pharmacol Ther. 2013 Dec 20. [Epub ahead of print]
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  4. Chowdhury UR, Holman BH, Fautsch MP. ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure in vivo. Invest Ophthalmol Vis Sci. 2013 Jul; 54(7):4892-9. Epub 2013 Jul 22.
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  5. Kuchtey J, Chowdhury UR, Uptegraft CC, Fautsch MP, Kuchtey RW. A de novo MYOC mutation detected in juvenile open angle glaucoma associated with reduced myocilin protein in aqueous humor. Eur J Med Genet. 2013 Jun; 56(6):292-6. Epub 2013 Mar 19.
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  6. Roy Chowdhury U, Holman BH, Fautsch MP. A novel rat model to study the role of intracranial pressure modulation on optic neuropathies. PLoS One. 2013; 8(12):e82151. Epub 2013 Dec 18
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  7. Bahler CK, Hann CR, Fjield T, Haffner D, Heitzmann H, Fautsch MP. Second-generation trabecular meshwork bypass stent (iStent inject) increases outflow facility in cultured human anterior segments. Am J Ophthalmol. 2012 Jun; 153(6):1206-13. Epub 2012 Mar 30.
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  8. Berdahl JP, Fleischman D, Zaydlarova J, Stinnett S, Allingham RR, Fautsch MP. Body mass index has a linear relationship with cerebrospinal fluid pressure. Invest Ophthalmol Vis Sci. 2012 Mar; 53(3):1422-7. Epub 2012 Mar 15.
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  9. Fleischman D, Berdahl JP, Zaydlarova J, Stinnett S, Fautsch MP, Allingham RR. Cerebrospinal fluid pressure decreases with older age. PLoS One. 2012; 7(12):e52664. Epub 2012 Dec 26.
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  10. Chowdhury UR, Jea SY, Oh DJ, Rhee DJ, Fautsch MP. Expression profile of the matricellular protein osteopontin in primary open-angle glaucoma and the normal human eye. Invest Ophthalmol Vis Sci. 2011 Aug; 52(9):6443-51. Epub 2011 Aug 16.
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  11. Chowdhury UR, Bahler CK, Hann CR, Chang M, Resch ZT, Romero MF, Fautsch MP. ATP-sensitive potassium (KATP) channel activation decreases intraocular pressure in the anterior chamber of the eye. Invest Ophthalmol Vis Sci. 2011 Aug; 52(9):6435-42. Epub 2011 Aug 16.
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  12. Lei Y, Garrahan N, Hermann B, Fautsch MP, Johnson DH, Hernandez MR, Boulton M, Morgan JE. Transretinal degeneration in ageing human retina: a multiphoton microscopy analysis. Br J Ophthalmol. 2011 May; 95(5):727-30. Epub 2010 Dec 22.
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  13. Last JA, Pan T, Ding Y, Reilly CM, Keller K, Acott TS, Fautsch MP, Murphy CJ, Russell P. Elastic modulus determination of normal and glaucomatous human trabecular meshwork. Invest Ophthalmol Vis Sci. 2011 Apr; 52(5):2147-52. Epub 2011 Apr 05.
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  14. Hann CR, Bentley MD, Vercnocke A, Ritman EL, Fautsch MP. Imaging the aqueous humor outflow pathway in human eyes by three-dimensional micro-computed tomography (3D micro-CT). Exp Eye Res. 2011 Feb; 92(2):104-11. Epub 2010 Dec 25.
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  15. Hann CR, Fautsch MP. The elastin fiber system between and adjacent to collector channels in the human juxtacanalicular tissue. Invest Ophthalmol Vis Sci. 2011 Jan; 52(1):45-50. Epub 2011 Jan 05.
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  16. Resch ZT, Hann CR, Cook KA, Fautsch MP. Aqueous humor rapidly stimulates myocilin secretion from human trabecular meshwork cells. Exp Eye Res. 2010 Dec; 91(6):901-8. Epub 2010 Oct 07.
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  17. Howell KG, Vrabel AM, Chowdhury UR, Stamer WD, Fautsch MP. Myocilin levels in primary open-angle glaucoma and pseudoexfoliation glaucoma human aqueous humor. J Glaucoma. 2010 Dec; 19(9):569-75.
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  18. Chowdhury UR, Madden BJ, Charlesworth MC, Fautsch MP. Proteome analysis of human aqueous humor. Invest Ophthalmol Vis Sci. 2010 Oct; 51(10):4921-31. Epub 2010 May 12.
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  19. Lei Y, Garrahan N, Hermann B, Fautsch MP, Johnson DH, Hernandez MR, Boulton M, Morgan JE. Topography of neuron loss in the retinal ganglion cell layer in human glaucoma. Br J Ophthalmol. 2009 Dec; 93(12):1676-9. Epub 2009 Aug 10.
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  20. Patel SV, Bachman LA, Hann CR, Bahler CK, Fautsch MP. Human corneal endothelial cell transplantation in a human ex vivo model. Invest Ophthalmol Vis Sci. 2009 May; 50(5):2123-31. Epub 2009 Jan 10.
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  21. Johnson M, Fautsch MP. Douglas H. Johnson: a tribute. Exp Eye Res. 2009 Apr; 88(4):620-30. Epub 2008 Nov 30.
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  22. Resch ZT, Fautsch MP. Glaucoma-associated myocilin: a better understanding but much more to learn. Exp Eye Res. 2009 Apr; 88(4):704-12. Epub 2008 Aug 29.
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  23. Hann CR, Fautsch MP. Preferential fluid flow in the human trabecular meshwork near collector channels. Invest Ophthalmol Vis Sci. 2009 Apr; 50(4):1692-7. Epub 2008 Dec 05.
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  24. Berdahl JP, Fautsch MP, Stinnett SS, Allingham RR. Intracranial pressure in primary open angle glaucoma, normal tension glaucoma, and ocular hypertension: a case-control study. Invest Ophthalmol Vis Sci. 2008 Dec; 49(12):5412-8. Epub 2008 Aug 21.
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  25. Ezzat MK, Howell KG, Bahler CK, Beito TG, Loewen N, Poeschla EM, Fautsch MP. Characterization of monoclonal antibodies against the glaucoma-associated protein myocilin. Exp Eye Res. 2008 Oct; 87(4):376-84. Epub 2008 Jul 12.
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  26. Bahler CK, Howell KG, Hann CR, Fautsch MP, Johnson DH. Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments. Am J Ophthalmol. 2008 Jan; 145(1):114-9. Epub 2007 Nov 07.
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  27. Fautsch MP, Johnson DH. Aqueous humor outflow: what do we know? Where will it lead us? Invest Ophthalmol Vis Sci. 2006 Oct; 47(10):4181-7.
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  28. Wren SM, Leske DA, Mutapcic L, Fautsch MP, Holmes JM. The effect of L-thyroxine supplementation in a neonatal rat model of ROP. Curr Eye Res. 2006 Jul-Aug; 31(7-8):669-74.
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  29. Fautsch MP, Vrabel AM, Johnson DH. Characterization of the Felix domesticus (cat) glaucoma-associated protein myocilin. Exp Eye Res. 2006 Jun; 82(6):1037-45. Epub 2005 Nov 10.
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  30. Fautsch MP, Vrabel AM, Johnson DH. The identification of myocilin-associated proteins in the human trabecular meshwork. Exp Eye Res. 2006 Jun; 82(6):1046-52. Epub 2005 Nov 11.
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  31. Leske DA, Wu J, Mookadam M, Chen Y, Fautsch MP, Holmes JM, Lanier WL. The relationship of retinal VEGF and retinal IGF-1 mRNA with neovascularization in an acidosis-induced model of retinopathy of prematurity. Curr Eye Res. 2006 Feb; 31(2):163-9.
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  32. Fautsch MP, Bahler CK, Vrabel AM, Howell KG, Loewen N, Teo WL, Poeschla EM, Johnson DH. Perfusion of his-tagged eukaryotic myocilin increases outflow resistance in human anterior segments in the presence of aqueous humor. Invest Ophthalmol Vis Sci. 2006 Jan; 47(1):213-21.
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  33. Park BC, Shen X, Fautsch MP, Tibudan M, Johnson DH, Yue BY. Optimized bacterial expression of myocilin proteins and functional comparison of bacterial and eukaryotic myocilins. Mol Vis. 2006; 12:832-40. Epub 2006 Jul 31.
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  34. Mutapcic L, Wren SM, Leske DA, Fautsch MP, Holmes JM. The effect of L-thyroxine supplementation on retinal vascular development in neonatal rats. Curr Eye Res. 2005 Dec; 30(12):1035-40.
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  35. Fautsch MP, Howell KG, Vrabel AM, Charlesworth MC, Muddiman DC, Johnson DH. Primary trabecular meshwork cells incubated in human aqueous humor differ from cells incubated in serum supplements. Invest Ophthalmol Vis Sci. 2005 Aug; 46(8):2848-56.
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  36. Berdahl JP, Leske DA, Fautsch MP, Lanier WL, Holmes JM. Effect of bicarbonate on retinal vasculature and acidosis-induced retinopathy in the neonatal rat. Graefes Arch Clin Exp Ophthalmol. 2005 Apr; 243(4):367-73. Epub 2004 Nov 19.
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  37. Mookadam M, Leske DA, Fautsch MP, Lanier WL, Holmes JM. Anti-thyroid methimazole in an acidosis-induced retinopathy rat model of retinopathy of prematurity. Mol Vis. 2005; 11:909-15. Epub 2005 Nov 02.
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  38. Floyd BN, Leske DA, Wren SM, Mookadam M, Fautsch MP, Holmes JM. Differences between rat strains in models of retinopathy of prematurity. Mol Vis. 2005; 11:524-30. Epub 2005 Jul 19.
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  39. Mookadam M, Leske DA, Fautsch MP, Lanier WL, Holmes JM. The anti-thyroid drug methimazole induces neovascularization in the neonatal rat analogous to ROP. Invest Ophthalmol Vis Sci. 2004 Nov; 45(11):4145-50.
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  40. Loewen N, Fautsch MP, Teo WL, Bahler CK, Johnson DH, Poeschla EM. Long-term, targeted genetic modification of the aqueous humor outflow tract coupled with noninvasive imaging of gene expression in vivo. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):3091-8.
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  41. Bahler CK, Fautsch MP, Hann CR, Johnson DH. Factors influencing intraocular pressure in cultured human anterior segments. Invest Ophthalmol Vis Sci. 2004 Sep; 45(9):3137-43.
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  42. Bahler CK, Hann CR, Fautsch MP, Johnson DH. Pharmacologic disruption of Schlemm's canal cells and outflow facility in anterior segments of human eyes. Invest Ophthalmol Vis Sci. 2004 Jul; 45(7):2246-54.
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  43. Fautsch MP, Vrabel AM, Peterson SL, Johnson DH. In vitro and in vivo characterization of disulfide bond use in myocilin complex formation. Mol Vis. 2004 Jun 27; 10:417-25.
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  44. Loewen N, Leske DA, Cameron JD, Chen Y, Whitwam T, Simari RD, Teo WL, Fautsch MP, Poeschla EM, Holmes JM. Long-term retinal transgene expression with FIV versus adenoviral vectors. Mol Vis. 2004 Apr 13; 10(35):272-80.
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  45. Leske DA, Wu J, Fautsch MP, Karger RA, Berdahl JP, Lanier WL, Holmes JM. The role of VEGF and IGF-1 in a hypercarbic oxygen-induced retinopathy rat model of ROP. Mol Vis. 2004 Jan 21; 10:43-50.
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  46. Fautsch MP, Silva AO, Johnson DH. Carbohydrate binding proteins galectin-1 and galectin-3 in human trabecular meshwork. Exp Eye Res. 2003 Jul; 77(1):11-6.
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  47. Loewen N, Bahler C, Teo WL, Whitwam T, Peretz M, Xu RF, Fautsch MR, Johnson DH, Poeschla EM. Preservation of aqueous outflow facility after second-generation FIV vector-mediated expression of marker genes in anterior segments of human eyes. Invest Ophthalmol Vis Sci. 2002 Dec; 43(12):3686-90.
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  48. Loewen N, Fautsch MP, Peretz M, Bahler CK, Cameron JD, Johnson DH, Poeschla EM. Genetic modification of human trabecular meshwork with lentiviral vectors. Hum Gene Ther. 2001 Nov 20; 12(17):2109-19.
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  49. Fautsch MP, Johnson DH. Characterization of myocilin-myocilin interactions. Invest Ophthalmol Vis Sci. 2001 Sep; 42(10):2324-31.
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  50. Session DR, Fautsch MP, Avula R, Jones WR, Nehra A, Wieben ED. Cyclin-dependent kinase 5 is expressed in both Sertoli cells and metaphase spermatocytes. Fertil Steril. 2001 Apr; 75(4):669-73.
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  51. Fautsch MP, Bahler CK, Jewison DJ, Johnson DH. Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment. Invest Ophthalmol Vis Sci. 2000 Dec; 41(13):4163-8.
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  52. Fautsch MP, Vrabel A, Rickard D, Subramaniam M, Spelsberg TC, Wieben ED. Characterization of the mouse TGFbeta-inducible early gene (TIEG): conservation of exon and transcriptional regulatory sequences with evidence of additional transcripts. Mamm Genome. 1998 Oct; 9(10):838-42.
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  53. Fautsch MP, Vrabel A, Subramaniam M, Hefferen TE, Spelsberg TC, Wieben ED. TGFbeta-inducible early gene (TIEG) also codes for early growth response alpha (EGRalpha): evidence of multiple transcripts from alternate promoters. Genomics. 1998 Aug 1; 51(3):408-16.
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  54. Fautsch MP, Perdok MM, Wieben ED. Production of SVP-1/-3/-4 in guinea pig testis. Characterization of novel transcripts containing long 5'-untranslated regions and multiple upstream AUG codons. J Biol Chem. 1997 Sep 26; 272(39):24691-5.
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  55. Hagstrom JE, Fautsch MP, Perdok M, Vrabel A, Wieben ED. Exons lost and found. Unusual evolution of a seminal vesicle transglutaminase substrate. J Biol Chem. 1996 Aug 30; 271(35):21114-9.
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  56. Specks U, Fass DN, Fautsch MP, Hummel AM, Viss MA. Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA. FEBS Lett. 1996 Jul 29; 390(3):265-70.
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  57. Eblen ST, Fautsch MP, Anders RA, Leof EB. Conditional binding to and cell cycle-regulated inhibition of cyclin-dependent kinase complexes by P27(KIP1). Cell Growth Differ. 1995 Aug; 6:915-25.
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  58. Fautsch MP, Eblen ST, Anders RA, Burnette RJ, Leof EB. Differential regulation of p34cdc2 and p33cdk2 by transforming growth factor-beta 1 in murine mammary epithelial cells. J Cell Biochem. 1995 Aug; 58(4):517-26.
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  59. Eblen ST, Fautsch MP, Burnette RJ, Snyder MR, Leof EB. Dissociation of p34cdc2 complex formation from phosphorylation and histone H1 kinase activity. Can Res. 1995; 55:1994-2000.
  60. Eblen ST, Fautsch MP, Burnette RJ, Joshi P, Leof EB. Cell cycle-dependent inhibition of p34cdc2 synthesis by transforming growth factor beta 1 in cycling epithelial cells. Cell Growth Differ. 1994 Feb; 5(2):109-16.
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  61. Fautsch MP, Thompson MA, Holicky EL, Schultz PJ, Hallett JB, Wieben ED. Conservation of coding and transcriptional control sequences within the snRNP E protein gene. Genomics. 1992 Dec; 14(4):883-90.
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  62. Fautsch MP, Wieben ED. Transcriptional regulation of the small nuclear ribonucleoprotein E protein gene. J Biol Chem. 1991 Dec 5; 34:23288-95.